Anti-TNIK Rabbit Polyclonal Antibody

Catalog # BOSSBS-4168R

Supplier: Bioss

Catalog # BOSSBS-4168R

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
TRAF2 and NCK interacting kinase
Antigen symbol:
TNIK
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Form:
liquid
Gene ID:
23043
Antigen synonyms:
TNIK|KIAA0551|TRAF2 and NCK-interacting protein kinase
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
Concentration:
1 ug/ul
Shipping temperature:
4 °C
Purification:
Purified by Protein A.
Size:
100 μg
Pk:
100 µl

Specifications

About this item

TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder and skin.

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: TNIK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat