Anti-ATG4D Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog # BOSSBS-4009R-A350

Supplier: Bioss

Catalog # BOSSBS-4009R-A350

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Autophagy Related 4D
Antigen symbol:
ATG4D
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 350
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Environmentally Preferable:
Cross adsorption:
No
Form:
liquid
Gene ID:
84971
Antigen synonyms:
AUTL4|APG4D|Cysteine protease ATG4D|autophagin-4|APG4-D
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Immunogen:
425-474/474
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ATG4D
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat