Anti-ROM-K Rabbit Polyclonal Antibody (Alexa Fluor® 750)

BOSSBS-2960R-A750

Anti-ROM-K Rabbit Polyclonal Antibody (Alexa Fluor® 750)

BOSSBS-2960R-A750

Antibody type:
Primary
Antigen name:
ROM-K
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 750
Flow cytometry:
Yes
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Rat
Epitope:
301-391/391
Form:
Liquid
Gene ID:
3758
Antigen synonyms:
Kir1.1|ROM K|ROMK 2|Kcnj1|inwardly rectying subfamily J member 1|ROM-K|IRK1_HUMAN|KCNJ 1|ROMK 1|inwardly rectying K+ channel|ATP-regulated potassium channel ROM-K|Potassium channel|Potassium channel inwardly rectying subfamily J member 1|Kir 1.1|potassium inwardly-rectying channel J1|ATP-sensitive inward rectier potassium channel 1|ROMK1|ATP sensitive inward rectier potassium channel 1|KCNJ|ROMK2|ROMK|Inward rectier K+ channel Kir1.1|ATP regulated potassium channel ROM K
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Molecular weight:
45 kDa
Storage temperature:
Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human ROM-K/KCNJ1
Tested applications:
ICC
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterised by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Type: Primary
Antigen: ROM-K
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 301-391/391
Host: Rabbit
Isotype: IgG
Reactivity: Rat