Anti-GZMA Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog # BOSSBS-2578R-A488

Supplier: Bioss

Catalog # BOSSBS-2578R-A488

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Granzyme A
Antigen symbol:
GZMA
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 488
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Gene ID:
3001
Antigen synonyms:
Ganzyme 1 cytotoxic T-lymphocyte-associated serine esterase 3,Ctla-3|SE1|TSP-1|Hf|Ctla3|TSP1
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Immunogen:
110-160/262
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: GZMA/Granzyme A
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat