Order Entry
Northern Ireland
ContactUsLinkComponent
20196 results for "tert-Butyl+propargyl+ether&amp"

20196 Results for: "tert-Butyl+propargyl+ether&amp"

L-Arginine hydrochloride, white crystalline powder

Supplier: MP Biomedicals

L-arginine is an amino acid that is necessary for the production of protein, also helps rid the body of ammonia (a waste product) and stimulates the release of insulin. In addition, L-arginine is used to make nitric oxide (a compound that relaxes the blood vessels).

Expand 3 Items
Loading...

SpectroMembrane® Thin-Film Sample Support Window Frames

Supplier: CHEMPLEX INDUSTRIES

SpectroMembrane® Thin-film sample support carrier frames consist of a thin-film sample support substance attached to a frame that serves as a carrier.

Expand 6 Items
Loading...

Methotrexate, yellow powder Ph. Eur., USP

Supplier: MP Biomedicals

Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.

Expand 2 Items
Loading...
Titrants and reagents for volumetric Karl Fischer titrations, HYDRANAL™, Fluka™

Titrants and reagents for volumetric Karl Fischer titrations, HYDRANAL™, Fluka™

Supplier: Honeywell Chemicals

HYDRANAL™-Composite is a frequently used pyridine-free Karl Fischer reagent. This one-component reagent has been proving its capabilities in volumetric titration for more than thirty five years in a large range of applications in the most diverse fields of research and industry.

The one component system have the following advantages:

Expand 92 Items
Loading...
SPE sorbents, CHROMABOND®

SPE sorbents, CHROMABOND®

Supplier: MACHEREY-NAGEL

The high purity CHROMABOND® adsorbents can be used for a self-filling of SPE columns or further analytical applications.

Expand 32 Items
Loading...

L(+)-Histidine monohydrochloride monohydrate, white powder

Supplier: MP Biomedicals

L-Histidine has been used to study cultures of the human T-lymphoblastic leukemia cell line MOLT-4 to study modulation of apoptosis. Exogenous histidine has been shown to enhance the biosynthesis of lovastatin by cultured Aspergillus terreus. Histidine has been utilised as a single nitrogen source to probe swarming in Pseudomonas aeruginosa on agar. An in vivo study has used L-histidine to diminish the net secretory response of the small intestine of of cholera toxin-challenged mice.

Expand 4 Items
Loading...
Recommended for You