145766 Results for: "di-Adamantylphosphine+triflate&pageNo=10&view=list"

Supplier: IKA

TWISTER is a universal and compact mixing device with magnetic drive. In the default version, TWISTER is a powerful single-position magnetic stirrer for mixing up to 5 litres at a maximum speed of 3000 min⁻¹ and a viscosity of up to 500 mPa·s. By connecting additional TWISTER stirring units (available as accessories, IKAA20112621), TWISTER can be expanded to a multi-position magnetic stirrer with up to 30 stirring positions. The stirring positions can be controlled either separately or simultaneously (leader-follower principle).

Supplier: MERCK PRODUCTION CHEMICALS

L-Arginine hydrochloride 98.5-101.0% (by perchloric acid titration), EMPROVE® EXPERT Ph. Eur., BP, JP, USP suitable for use as excipient, SAFC®

Supplier: GRANT INSTRUMENTS

A range of eco-friendly, refrigerated/heating circulating baths with an intuitive user-interface and sleek design. Units offer significant running cost savings whilst delivering powerful cooling when needed. Choice of 2 models with temperature range of –25 to +150 °C (model dependent*). Ideal for applications in pharmaceutical, education, industrial and life science areas for use with mini pilot plant reactors, cooling rotary evaporators, replacing running tap water cooling, immersing small samples, photometry, chromatography systems, sample preparation, general cooling, reaction chemistry, temperature control, semi-conductor manufacturing, rheometry, refractometry and electrophoresis cooling.

Supplier: ProSci Inc.

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.

Supplier: ProSci Inc.

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.

Supplier: Mettler - Toledo

These instruments with two or three channels are modularly expandable with additional measurement parameters at any time.

Supplier: TOSOH BIOSCIENCE

TSKgel® SW size exclusion columns are widely used for aqueous analysis and isolation of proteins, antibodies, enzymes, nucleic acids and other biological macromolecules.

Supplier: LGC Standards PROMOCHEM

ESTRIOL IMP. F (EP):16-EPI-ESTRIOL 1 * 100 mg

Supplier: BD Medical

Syringe 10ml 20Gx1 inch Luer-Lok 1 * 400 items

Supplier: witeg Labortechnik

WHM12019,Aℓ-case Heating Mantles with Controller, 450℃, for 10,000ml Spherical flask(DU) 1 * 1 items

Supplier: DWK Life Sciences

Valve discharge for DURAN Group dispenser PRO 2,5/5/10ml (PFA/Borosilicate glass/Platin-Iridium) 1 * 1 items

Supplier: VITLAB

Volumetric flask, PP, class B, with screw cap, PP, 100 mL 1 * 2 items

Supplier: VITLAB

Volumetric flask, PMP, class B, with stopper NS 12/21, PP, 50 mL 1 * 2 items

Supplier: BANDELIN-ELECTRONIC

titanium probe TS 106, titanium probe, dia. 6 mm, for HD 4050/4100/4200 1 * 1 items

Supplier: ProSci Inc.

Hemagglutinin Monoclonal Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.

Supplier: NEUBERT VOLUME GLASSWAERE

flat bottom glass 36x1,4x120mm 54mm with ring mark fused straight bottom ca.45ml ring mark mark at 54+-0,5mm inside measured straight bottom straight rim fused (pour point glass ) from Boro 3.3 1 * 1 items

Supplier: Corning

SQUARE BOTTLE 500ML HDPE NA H147 Ø29, 10MG SODIUM THIO, LABEL WH & TAMPER EVIDENT HINGED PLUG RE, IONISED 1 * 100 items

Supplier: HIRSCHMANN

Flask volumetric, capacity 20ml, USP individual certificate, class A, graduated, conformity certified. 1 * 1 items

Supplier: ProSci Inc.

This antibody is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound protein. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product C4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival. C4d antibody, combined with antibody to C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Supplier: ProSci Inc.

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells By similarity. Phosphorylates heat shock factor protein 4 (HSF4). /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it./Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. Required for stress-induced neuronal apoptosis and the pathogenesis of glutamate excitotoxicity

Supplier: Hach

Robust and intuitive portable meters, instilling confidence in reporting and managing your results.

Supplier: witeg Labortechnik

Heating Mantles WHM, for beakers 10.000 ml,without integrated power controller, temp. range 450C,1400 W, power supply 230 V 1 * 1 items

Supplier: Greiner Bio-One

PIPET 5ML SER. PLAS/PLAS TRIPLE PACKING 1 * 100 items

Supplier: DUPERTHAL

Exhaust air monitor optional with ventilator: Easy ventilation and monitoring of the venting system for safety cabinets. A sensor monitors the air flow speed/stream and gives a visual or audible signal if the value drops below the set-point value. The complete exhaust monitoring unit is supplied pre-assembled (ready to plug in) and is placed directly on the cabinet. The set-point value for the air stream flow rate is preset in the factory and can be individually adjusted by the pressure difference socket. In addition to the volumetric flow rate the power supply is also monitored. The system includes two floating contacts (24 V/2 A) for signal transmission to an external control room. Internal storage accumulator supplies the monitoring systems for 4 hours in the event of a power failure, display with easy fault indication and enables permanent monitoring according to DIN EN 1946-7. The housing is made from powder-coated sheet steel, silver pearl glimmer.

Supplier: MARIENFELD

Plate, staining ,12 place ,79 x 63 x 4 mm dimension,made of pressed glass,cavity 16mm, diameter 2mm depth 1 * 15 items

Supplier: UVEX

BRILLE I-WORKS i-5 Zertifiziert nach EN 166 (persönlicher Augenschutz) und EN 170 (UV-Schutz-Filter) Kennzeichnung: W 166 FT CE – 2C-1,2 W1 FTKN CE UV400 – 100 % Schutz vor gefährlicher UVA- und UVB-Strahlung bis 400 nm 1 * 1 items

Supplier: ProSci Inc.

Receptors for the Fc region of immunoglobin G (Fc gamma R) are divided into three classes and Fc gamma RIII is a multifunctional, low/intermediate affinity receptor. In humans, Fc gamma RIII is expressed as two distinct forms (Fc gamma RIIIA and Fc gamma RIIIB) that are encoded by two different but highly homologous genes in a cell type-specific manner. Fc gamma RIIIB is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas Fc gamma RIIIA is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. The Fc gamma RIIIA receptor is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), mast cell degranulation, and clearance of immune complexes. Fc gamma RIIIA has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. Aberrant expression or mutations in this gene is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. In humans, it is a 50 -70 kD type I transmembrane activating receptor. The Fc gamma RIIIA cDNA encodes 254 amino acid including a 16aa signal sequence, 191 amino acid ECD with two C2-type Ig-like domains, five potential N-glycosylation sites, a 22 amino acid transmembrane sequence and a 25 amino acid cytoplasmic domain.

Supplier: ProSci Inc.

Hemagglutinin Monoclonal Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.

Supplier: Thermo Fisher Scientific

Choose Thermo Scientific™ SureSTART™ 2 ml glass crimp top vials, performance level 3, for high performance applications, when sensitivity is a must. Our level 3 vials are our highest performance vials, designed to protect your most valuable samples and deliver consistent, reproducible results for your most demanding GC-MS. These 2 ml clear glass crimp vials are specification certified to ensure their physical dimensions and autosampler compatibility. Use 11 mm crimp caps and septa to seal these vials. Seal and remove your crimp caps using Thermo Scientific manual and electronic crimpers and decrimpers. These vials meet all requirements of US, EU, JPN Pharmacopeia. Buy in bulk for greater savings.

Supplier: MP Biomedicals

FastRNA® Pro Blue Kit is used to isolate total RNA from gram positive and gram negative bacteria. Isolated RNA is suitable for RT-PCR analysis and other downstream applications.