21441 Results for: "Welch+by+Gardner+Denver&pageNo=11"
Stereo Microscope, Mantis PIXO
Supplier: VISION ENGINEERING
PIXO is a eyepiece-less optical stereo microscope with integrated high-definition digital camera and dynamic view optics.
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21 COMPONENTS MIX 1 * 2 Ampoul
Supplier: CUSTOM MADE CHEMICALS LAB
21 COMPONENTS MIX 1 * 2 Ampoul
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PIPETTE MEASURING AR-GLAS 5 MARKS 1 * 1 items
Supplier: DWK Life Sciences
PIPETTE MEASURING AR-GLAS 5 MARKS 1 * 1 items
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Microplate readers, Varioskan™ LUX
Supplier: THERMO LABSYSTEMS LIFE SCIENCE
Varioskan™ LUX comes equipped with a range of measurement technologies including absorbance, fluorescence intensity and FRET as standard, and with optional luminescence, AlphaScreen and time-resolved fluorescence (TRF) modules. The instrument selects the measurement wavelength using filters or monochromators, depending on which is optimal for each measurement technology.
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Anti-STK11 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Supplier: Bioss
Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.
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Anti-STK11 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.
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PRINTED CIRCUIT BOARD 1 * 1 items
Supplier: IKA
PRINTED CIRCUIT BOARD 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 2.00MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 2.00MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 5.60MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 5.60MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 4.00MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 4.00MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 9.50MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 9.50MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 250µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 250µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 355µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 355µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 11.2MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 11.2MM S.S./S. 1 * 1 items
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Anti-STK11 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Supplier: Bioss
Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.
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Cooled Incubators, Series 2
Supplier: LMS
LMS Series 2 cooled incubators are temperature controlled cabinets with fan assisted air circulation via a pre-mixing chamber. The units have a white enamelled sheet steel exterior, high impact plastic interior and polyurethane foam insulation, and feature a door lock and magnetic door gasket. The corrosion resistant inner chamber is easy to clean, disinfection procedures are detailed in the user manual.
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Water baths and circulators, stainless steel, Optima™
Supplier: GRANT INSTRUMENTS
The Grant Optima™ range consists of both general purpose and advanced performance thermostats combined with premium stainless steel baths (drain tap on 12, 18, 26 and 38 litre baths). Stirred circulation within the bath ensures excellent temperature stability and uniformity. Units can also be used with accessory C1G and C2G immersion coolers for operation below ambient temperatures.
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Biological upright microscopes, fixed Koehler LED, BA 210 LED
Supplier: MOTIC
Microscopes for basic work in biology life science. Fixed Koehler set-up gives adequate power resources for upgrading the microscope with contrast methods like phase contrast, polarisation or darkfield. The Motic BA 210 is a robust, ready to use with pre-installed set-up of optics and 3 W LED illumination.
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SIEVE ASTM.E11-95 8X2INCH 150µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 150µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 600µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 600µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 850µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 850µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 16.0MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 16.0MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 31.5MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 31.5MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 45.0MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 45.0MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 3.35MM S.S./S. 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 3.35MM S.S./S. 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 025µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 025µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 125µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 125µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 300µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 300µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 212µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 212µM S.S./S.S 1 * 1 items
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SIEVE ASTM.E11-95 8X2INCH 425µM S.S./S.S 1 * 1 items
Supplier: ENDECOTTS
SIEVE ASTM.E11-95 8X2INCH 425µM S.S./S.S 1 * 1 items