Supplier: Bioss

C8orf74 (chromosome 8 open reading frame 74) is a 294 amino acid protein encoded by a gene that maps to human chromosome 8p23.1. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Supplier: Bioss

C8orf74 (chromosome 8 open reading frame 74) is a 294 amino acid protein encoded by a gene that maps to human chromosome 8p23.1. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukaemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Supplier: Bioss

C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Supplier: Binder

Two versions of these incubators with electronically controlled APT.line™ preheating chamber are available depending on the application: The BD series with natural convection for all standard applications and the BF series with forced convection for applications with high load density.

Supplier: Bioss

C8orf74 (chromosome 8 open reading frame 74) is a 294 amino acid protein encoded by a gene that maps to human chromosome 8p23.1. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Supplier: Bioss

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyses triglycerides in plasma and transfers the fatty acids to tissues. The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase. The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver.

Supplier: Bioss

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf31 gene product has been provisionally designated C8orf31 pending further characterization.

Supplier: MACHEREY-NAGEL

These quantitative filter papers are made from refined pulp and linters. They are purified in a highly developed clean-up process to remove organic and inorganic impurities. This ensures a low ash content of <0,01 %. They are consistent performance and give safe results in gravimetric analyses.

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

Supplier: GA

Transparent cryogenic self-laminating labels for thermal transfer printers. Their clear laminate protects the printed information from alcohols and detergents to ensure the secure identification of tubes and cryo vials. These labels will also withstand prolonged storage under cryogenic conditions, including in liquid phase and vapor phase liquid nitrogen.

Supplier: ANTIBODIES.COM

Human SLC31A1/CTR1 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human SLC31A1/CTR1 in serum, plasma, and other biological fluids.

Supplier: Testo

Compact professional measuring instrument from the Testo Smart Probes series for use with smartphones/tablets.

Supplier: Thermo Fisher Scientific

Finnpipette™ F2 offers superior robustness and durability even in the most demanding applications.

Supplier: Cytiva

Immobiline™ DryStrip gels (IPG strips) are used for isoelectric focusing (IEF), run as the first dimension of 2-D electrophoresis or as a separate application. IPG strips contain a preformed pH gradient immobilised in precast polyacrylamide gels on a plastic backing. A comprehensive range of overlapping IPG strips covering narrow, medium, and wide pH ranges are available in various strip lengths, and the strips are individually packaged and bar coded for convenient handling and sample tracking.

Supplier: ANTIBODIES.COM

Rat SLC31A1/CTR1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat SLC31A1/CTR1 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: ANTIBODIES.COM

Mouse KSR1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse KSR1 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: ANTIBODIES.COM

Human LILRA3 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human LILRA3 in serum, plasma, and other biological fluids.

Supplier: FRISTADS KANSAS

Water repellent trousers made of polyester and cotton. The reinforcement is made of 100% polyamide.

Supplier: Binder

The M Series Avantgarde.Line units have a maximum of 300 °C and various advanced programming options ensure these material test chambers are ideal for material and aging tests. The units have a high air flow and their powerful fans ensure rapid heating.

Supplier: VWR Collection

INCU-Line® microbiological incubators are designed to cultivate organisms at homogeneous temperatures. They have a temperature range of 5 °C above ambient to 100 °C and can, for instance, be used for microbiological tests, germ count determination and ageing/heated storage.

Supplier: Merck

LiChrospher® is Merck's reliable and versatile, traditionally-produced, spherical silica. LiChrospher® is available with different modifications.

Supplier: Bioss

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesised as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesised as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesised as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.

Supplier: Bioss

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesised as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesised as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesised as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.

Supplier: Bioss

Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It's expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.

Supplier: Binder

These energy efficient cooled incubators have been designed for use in the temperature range from 4 to 100 °C. They feature a Peltier cooling system for finely controlled cooling down to 4 °C together with powerful conventional heating. The unit has easy to clean stainless steel interior and inner safety glass door. The incubators are ideal for use in microbiology, genetics, zoology, food and beverage industries, medicine, forensics, pharmaceutical and cosmetic industries. USB port for reading data and ethernet interface for communication software APT-COM™ DataControlSystem.

Supplier: Binder

Avantgarde. Line incubators ensure stable and reliable incubation of microbiological cultures and guarantee reproducible results for routine tests in the laboratory – even high batch throughputs and with long-term operation. Avantgarde. Line BD models have natural convection ensuring rapid temperature equalisation after the door is opened. The BF models have forced convection via a fan. The APT.line™ pre-heating chamber technology gives homogeneous temperature distribution, excellent temperature uniformity and low fluctuation. Units up to 115 litres can be stacked on top of each other to save space. The units have 60 mm insulation which lowers energy consumption and increases performance. All models have a stainless steel chamber with an ergonomic door opening system.

Supplier: Bioss

Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin-1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome; a developmental disorder characterised by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt's lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.

Supplier: JULABO GmbH

High temperature circulators can be used for temperature applications up to 400 °C; units provide powerful heating capacities for shortest heat-up times and rapid compensation of endothermic reactions. Applications include use with reactors, autoclaves, distillation columns, mini plant installations, pilot plants and production facilities. Because of the closed circuit system oxidation is reduced and unpleasant odours and vapours do not escape, even at high temperatures.

Supplier: ANTIBODIES.COM

Porcine BNP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of porcine BNP in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: ANTIBODIES.COM

Human BNP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human BNP in serum, plasma, tissue homogenates, and other biological fluids.