5282 Results for: "Vinblastine+sulphate&pageNo=31"

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The black jacket is available with different accent and piping colours.

Supplier: SONICS MATERIALS

A wide range of probes for a variety of applications is available, including stepped and tapered microtips and also probes for processing in microplates.

Supplier: Sartorius

These qualitative filter papers are essentially used for analytical purposes and routine analyses, whenever no gravimetric analyses are required. They are wet-strengthened and can be used for pressure and vacuum filtration. They are made of refined pulp and linters with an >95% alpha-cellulose content, are very pure with an ash content <0,1%.

Supplier: MACHEREY-NAGEL

NUCLEODUR® C8 Gravity is an octyl modified silica phase with a high density coverage, using for HPLC.

Supplier: MACHEREY-NAGEL

NUCLEODUR® C18 Pyramid is an octadecyl modified silica phase with polar endcapping, especially designed for use in eluent systems of up to 100% water.

Supplier: MERKLINGER PRAZISION WERKZEUG

This column-packing technology is based on a combination of vacuum suction with subsequent column bed compression that stabilises the packing. A common water-jet pump is used to generate the vacuum. The sorbent slurry is sucked through a packing reservoir into the column by applying low pressure at the bottom end of the column.

Supplier: TEMPSHIELD

These hand-specific gloves protect hands and arms against the hazards of working in and with ultra-cold temperatures down to –196 °C. Lightweight, breathable, and comfortable, they provide protection from liquid splashes and cryogenic temperatures but are not safe for immersion in cryogenic liquids.

Supplier: FRISTADS KANSAS

Work overalls made from 65% polyester and 35% cotton. With napped inner.

Supplier: MACHEREY-NAGEL

NUCLEODUR® Sphinx RP is a bifunctional RP phase with a balanced ratio of propylphenyl and C18 ligands, using in HPLC.

Supplier: GA

Removable deep-freeze labels for vials, tubes, and freezer boxes. These thermal transfer freezer labels have a glove-friendly adhesive that ensures the labels can be easily removed without leaving any adhesive residue.

Supplier: FRISTADS KANSAS

Overalls made from 65% polyester, 35% cotton, with soft nap on reverse side.

Supplier: VARIAN

The PLRP-S family of products consists of a range of pore sizes and particle sizes, all with identical chemistry and fundamental adsorptive characteristics. The particles are inherently hydrophobic so there is no bonded phase, alkyl ligand required for reversed-phase separations. This gives a highly reproducible material that is free from silanols and heavy metal ions. Within the extensive product range are columns suitable for analytical separations and preparative purifications.

Supplier: Avantor Fluid Handling

Versatile multichannel pumps for accurate low-flow fluid delivery – with an intuitive touch-screen interface.

Supplier: asecos

Fireproof safety cabinets, classified type 30 (fire resistant up to 30 minutes), safe, durable, robust and convenient with transport base and bicoloured cabinet design.

Supplier: Bioss

C22orf31, also known as HS747E2A or bK747E2.1, is a 290 amino acid protein encoded by a gene located on human chromosome 22, which contains over 500 genes and about 49 million bases. As the second smallest human chromosome, chomosome 22 contains a wide variety of genes with numerous functions. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.

Supplier: Bioss

Nck is a highly conserved, oncogenic protein. It is a common target for the action of different surface receptors, encoding one SH2 and three SH3 domains, the Src homology motifs found in nonreceptor tyrosine kinases, Ras GTPase activating protein, phosphatidylinositol 3 kinase, and phospholipase Cg. Nck is widely expressed in various tissues and in cell lines from human, murine, and rat origins. Nck is phosphorylated on tyrosine, serine, and threonine residues in response to stimulation of EGF and PDGF in A431 and NIH 3T3 cells respectively. Like other SH2 containing proteins, Nck is associated with tyrosine autophosphorylated EGF or PDGF receptors via its SH2 domain. Overexpression of Nck leads to transformation of NIH 3T3 cells.

Supplier: Bioss

Nck is a highly conserved, oncogenic protein. It is a common target for the action of different surface receptors, encoding one SH2 and three SH3 domains, the Src homology motifs found in nonreceptor tyrosine kinases, Ras GTPase activating protein, phosphatidylinositol 3 kinase, and phospholipase Cg. Nck is widely expressed in various tissues and in cell lines from human, murine, and rat origins. Nck is phosphorylated on tyrosine, serine, and threonine residues in response to stimulation of EGF and PDGF in A431 and NIH 3T3 cells respectively. Like other SH2 containing proteins, Nck is associated with tyrosine autophosphorylated EGF or PDGF receptors via its SH2 domain. Overexpression of Nck leads to transformation of NIH 3T3 cells.

Supplier: Bioss

Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf71 gene product has been provisionally designated C9orf71 pending further characterisation.

Supplier: Bioss

L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Supplier: LEICA MICROSYSTEMS

The objective lens is a critical part of the microscope optics. The microscope objective is positioned near the sample, specimen, or object being observed. It has a very important role in imaging, as it forms the first magnified image of the sample.

Supplier: Bioss

The Ca²⁺/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CaMKI Beta (Ca²⁺/calmodulin-dependent protein kinase type 1B), also known as PNCK (pregnancy up-regulated non-ubiquitously expressed CaM kinase) or BSTK3, is a 343 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. Existing as multiple alternatively spliced isoforms, CaMKI Beta functions to catalyse the ATP-dependent phosphorylation of CaMKI, an event that activates CaMKI activity and may be important for Ca²⁺-triggered Signalling cascades within the cell. The gene encoding CaMKI Beta maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1000 genes.

Supplier: Bioss

Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf50 gene product has been provisionally designated C9orf50 pending further characterisation.

Supplier: Bioss

E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.

Supplier: Bioss

E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.

Supplier: FRISTADS KANSAS

Work trousers made from Polydex®, 100% polyester, with napped inner.

Supplier: FRISTADS KANSAS

Gilets made from 65% polyester and 35% cotton; napped inner.

Supplier: FRISTADS KANSAS

Overalls made from 65% polyester and 35% cotton, with soft nap on reverse side.

Supplier: ANTIBODIES.COM

Mouse ATP6V1E1 ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse ATP6V1E1 in serum, plasma, and other biological fluids.

Supplier: biotechrabbit

Expression kits for PCR-based generation of linear templates.

Supplier: ProSci Inc.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX31 is a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants.