5288 Results for: "Vinblastine+sulphate&pageNo=31"

Supplier: Bioss

IQCJ (IQ domain-containing protein J) is a 159 amino acid protein that contains one IQ domain. Existing as four alternatively spliced isoforms, the gene encoding IQCJ maps to human chromosome 3q25.32. Chromosome 3 houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Supplier: Bioss

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Supplier: HELLMA

Hellma® high precision quartz glass makro cylinder cell temperature-controlled for absorption measurements in the UV/Vis range, 10 mm path length, with inlet and outlet nozzle.

Supplier: Bioss

Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf62 gene product has been provisionally designated C20orf62 pending further characterization.

Supplier: Hospidex

Sharpsafe®, historic pioneer in protecting against the risk of sharps injuries and sustainability in medical waste packaging management, presents the recycled 5th generation needle containers.

Supplier: Bioss

Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

Supplier: Bioss

Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

Supplier: Bioss

Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

Supplier: Cytiva

Ettan™ IPGphor™ 3 is a fully integrated isoelectric focusing (IEF) system optimised to deliver high throughput, speed, reproducibility, and high protein-loading capacity. Ettan™ IPGphor™ 3 is optimised for easy handling of CyDye™ labelled proteins and other light-sensitive samples, and provides temperature control critical for reproducibility in 2-D DIGE experiments.

Supplier: Merck

Spectroquant® Prove spectrophotometers are designed for any type of water analysis - wastewater, process water or drinking water and beverages.

Supplier: VWR Collection

The W10 heating plate, with its sleek compact design, accommodates two rows of up to 40 slides in total. The heating plate is very useful as a stretch bench for mounting, stretching and drying paraffin sections on slides, fixing bacterial smears, and heating fluid samples in Petri dishes. The black anodised surface provides an excellent visual contrast. The working plate is made of solid 8 mm aluminium with black anodised surface and ensures a constant, homogenous temperature over the entire heating surface. The touch display and switch are protected from water and paraffin. The unit has over-temperature protection for extra safety. Temperature adjustment and power On/Off switch, with control light for 'On' mode, are conveniently located at the front of the unit.

Supplier: VWR Collection

DRY-Line® drying ovens are designed for all standard drying and tempering tasks as well as sterilising glassware. They have a temperature range between 50 to 300 °C and are intended for use in biological, chemical, medical, pharmaceutical and physical laboratories.

Supplier: MACHEREY-NAGEL

NUCLEODUR® C18 PolarTec is an octadecyl modified silica phase with embedded polar group for HPLC.

Supplier: TEKNOMEK

Our range of sensor operated wash troughs are manufactured from 304 grade stainless steel with a fully welded design for maximum hygiene. Choose from knee, battery or mains operation to suit your needs.

Supplier: LABCONCO

Fast-Freeze® flasks for FreeZone® freeze dry systems are designed to be easier to handle, faster to load, and more convenient to use in the laboratory for freeze drying.

Supplier: FRISTADS KANSAS

Robust trousers made from 65% polyester and 35% cotton, with soft nap on reverse side.

Supplier: Thermo Fisher Scientific

Achieve repeatable and consistent liquid chromatography (LC) separations using Thermo Scientific™ Syncronis™ C18 columns.

Supplier: Portwest

Standard V-necked coats, made of Fortis Plus fabric consisting of 65% polyester and 35% cotton.

Supplier: Merck

All Spectroquant® test kits can be used with the Prove range of spectrophotometers and Nova 60/60A instruments. Tests can be used not only on photometers and spectrophotometer from Merck, but also on photometers and spectrophotometers from other suppliers (programming details available on request). Spectroquant® cell test kits.

Supplier: Thermo Fisher Scientific

Ambient measurements or monitoring of laboratory equipment.

Supplier: Thermo Fisher Scientific

Natural tubes are made from 100% virgin PP to help ensure maximum clarity for biological-based work.

Supplier: FRISTADS KANSAS

This outdoor jacket is made of anti-pilling polyester, jersey bonded fabric, with micro fleece inside. The jacket is windproof, water repellent, breathable and quick drying.

Supplier: FRISTADS KANSAS

Vest made from 65% polyester and 35% cotton; napped inner.

Supplier: FRISTADS KANSAS

Gilets made from 65% polyester and 35% cotton; napped inner.

Supplier: Thermo Fisher Scientific

Contains a C4 linker which allows for superior alignment of the phenyl ring with aromatic molecules. Get excellent retention and unique selectivity for aromatic and moderately polar analytes with Thermo Scientific™ Hypersil GOLD™ Phenyl reversed phase HPLC columns.

Supplier: MACHEREY-NAGEL

NUCLEODUR® C8 ec is a medium density monomeric octyl modified silica phase for HPLC.

Supplier: MICROSOLV

RSA™ (Reduced Surface Activity) high quality and extremely consistent autosampler vials and caps due to reduced surface activity glass manufacturing and control processes. Excellent for low abundance or low dosage form analytes or samples that are pH sensitive, or basic in nature.

Supplier: FRISTADS KANSAS

Functional vests made from 65% polyester and 35% cotton; with napped inner.

Supplier: VWR Collection

VENTI-Line® drying ovens are designed for all standard drying and tempering tasks as well as sterilising glassware. They have a temperature range between 50 to 300 °C and are intended for use in biological, chemical, medical, pharmaceutical and physical laboratories.

Supplier: VWR Collection

PE bags, transparent. These sterile sampling bags provide a secure, contaminant-free pliant container that ensures dependable analysis results. Economical and efficient way to collect, contain and carry samples. With these bags, the user can bring sterile sampling bags into a cleanroom without any worries about contamination. The bags are double-pouched so the user can remove the outer bag before entering the cleanroom, which minimises the number of bags exposed.