234813 Results for: "VWR® High Performance Single Channel Pipettors and Pipettor Kits"

Supplier: IONICS

Pre-bent titanium 1/8 inch tube with pre-swaged nuts and ferrules. Instructions are included. 1 * 1 items

Supplier: PerkinElmer

9MM 2ML RED RUB SCRCAP/CLEAR VIAL(100) 1 * 100 items

Supplier: ProSci Inc.

CD45, also referred to as CD45R and PTPRC (Protein tyrosine phosphatase receptor type C), has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Along with other members of the PTP family, it regulates a number of cellular processes including cell differentiation, growth and mitotic cycle, and is an essential regulator of B- and T-cell antigen receptor-mediated activation.

Multiple isoforms of CD45 are distributed throughout the immune system and arise due to alternative splicing of exons located in the N-terminus. CD45RA contains the A exon and is a naive T-cell marker which may help prevent autoimmune disease. CD45RB contains B and stains most leukemias and lymphomas. CD45RC contains C and stains thymocytes, monocytes and dendritic cells. CD45RO doesn't contain A, B or C and is a marker of activated T-cells that can be used to classify and diagnose and classify lymphomas. This antibody will bind to all CD45 isoforms. The variation in these isoforms is localized to the extracellular domain, with the intracellular domain being conserved. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Supplier: ProSci Inc.

CD45, also referred to as CD45R and PTPRC (Protein tyrosine phosphatase receptor type C), has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Along with other members of the PTP family, it regulates a number of cellular processes including cell differentiation, growth and mitotic cycle, and is an essential regulator of B- and T-cell antigen receptor-mediated activation.

Multiple isoforms of CD45 are distributed throughout the immune system and arise due to alternative splicing of exons located in the N-terminus. CD45RA contains the A exon and is a naive T-cell marker which may help prevent autoimmune disease. CD45RB contains B and stains most leukemias and lymphomas. CD45RC contains C and stains thymocytes, monocytes and dendritic cells. CD45RO doesn't contain A, B or C and is a marker of activated T-cells that can be used to classify and diagnose and classify lymphomas. Clone 2B11 antibody will bind to all CD45 isoforms. The variation in these isoforms is localized to the extracellular domain, with the intracellular domain being conserved. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Supplier: ProSci Inc.

This antibody is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound protein. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product C4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival. C4d antibody, combined with antibody to C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Supplier: ProSci Inc.

This mAb recognises a protein of 41 kDa, which is identified as TDP2, or ETS1 associated protein II. It is a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. catalyses the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

Supplier: SciLabware

Assembly complete soxhlet 60ml, condenser, cx7/05/sc, flask, fr150/3s. 1 * 1 items

Supplier: Hach

Reagent set, water-in-oil test 'n tube, 50 tests 1 * 50 Tests

Supplier: Thermo Fisher Scientific

RELAY ASSEMBLY 240 VOLTS 1 * 1 items

Supplier: PHC Corporation

stacking plate for stacking MCO170/MCO19M/MCO18AC/MCO230 onto MCO230 1 * 1 items

Supplier: MICRONOVA

BUCKET BINDER DOUBLE BUCKET DK BLUE/RED 1 * 1 SET

Supplier: Amarell

Meteorological Extreme therm., minimum type, blue glass index, DIN 58653, -40+40:0,5C, with glass saddle and metal cap, milk glass scale, cap. lens front, blue reflecting, alcohol filled, 290mm long, diameter 18+/-0,5mm, suitable for government veri 1 * 1 items

Supplier: OPTIMIZE TECHNOLOGIES

OPTI-LYNX Guard Column Holder 1 * 1 SET

Supplier: MACHEREY-NAGEL

VISOCOLOR Powder Pillows pH reagent set for photometric determination measuring range: pH 6.2-8.2 100 determinations 1 * 100 items

Supplier: Amarell

Areometer, DIN 12791, M50, 0,65-0,70:0,0010g/cm , ref. temp. 20C, without thermometer max. 270mm long, suitable for government ver ification 1 * 1 items

Supplier: Amarell

Areometer, DIN 12791, M50, 1,00-1,05:0,0010g/cm , ref. temp, 20C, without thermometer max. 270mm long, suitable for government ver ification 1 * 1 items

Supplier: OPTIMIZE TECHNOLOGIES

OPTI-LYNX ALL-IN-ONE DIRECTCON 1 * 1 SET

Supplier: OPTIMIZE TECHNOLOGIES

OPTI-LYNX ALL-IN-ONE COLUMN KI 1 * 1 SET

Supplier: MACHEREY-NAGEL

VISOCOLOR Powder Pillows total Chlorine reagent set for photometric determination measuring range: 0.03-6.00 mg/L Cl2 100 determinat ions 1 * 100 items

Supplier: IONICS

Pre-bent titanium 1/8 inch tube with pre-swaged nuts and ferrules. Instructions are included. Order APK 68336-01 if customer has not installed improved Heater Cover design 1 * 1 items

Supplier: MACHEREY-NAGEL

VISOCOLOR Powder Pillows free Chlorine reagent set for photometric determination measuring range: 0.03-6.00 mg/L Cl2 100 determinati ons 1 * 100 items

Supplier: MACHEREY-NAGEL

VISOCOLOR Powder Pillows total Chlorine reagent set for photometric determination measuring range: 0.03-6.00 mg/L Cl2 1000 determina tions 1 * 1.000 items

Supplier: VARIAN

Low flow concentric glass nebulizer (micromist). 1/pk. provides aspirated free flow of .2 ml/min. includes sample and gas inlet fitt ings 1 * 1 items

Supplier: Thermo Scientific

General Purpose Pro Centrifuges Cell Therapy Systems (CTS™) Series consist of equipment, documentation, and certifications, as well as compliance services that support Good Manufacturing Practice (GMP) requirements. The CTS Series helps you get up and running faster, stay compliant and current with all necessary regulatory certifications, navigate regulatory audits, and stay on schedule, taking cell therapy from discovery to clinical research and commercial manufacturing. The refrigerated 4 L (4×1000 ml) floor standing and bench models are designed to meet the needs of today’s rapid-fire discoveries, with updates to help get research done quickly, consistently, and reliably.

Supplier: MARKET SOURCE PART PROCESS

Lentivirus medium-scale packaging service for: pLV[Exp]- EFSdCas9/ VPR(ns):T2A:TagBFP2(ns):P2A: Puro (VB200330-7209ngp) 1 * 1 items

Supplier: Thermo Scientific

General Purpose Pro Centrifuges Cell Therapy Systems (CTS™) Series consist of equipment, documentation, and certifications, as well as compliance services that support Good Manufacturing Practice (GMP) requirements. The CTS Series helps you get up and running faster, stay compliant and current with all necessary regulatory certifications, navigate regulatory audits, and stay on schedule, taking cell therapy from discovery to clinical research and commercial manufacturing. The refrigerated 4 L (4×1000 ml) floor standing and bench models are designed to meet the needs of today’s rapid-fire discoveries, with updates to help get research done quickly, consistently, and reliably.

Supplier: TIGER-VAC

carriage assembly for CWR-10(CV) containment vacuum for Novartis made entirely of stainless steel type 304 electropolished Complete with grey conductive wheels (non-marking) 1 * 1 items

Supplier: SONICS MATERIALS

TOOL SET 1 * 1 items

Supplier: MARKET SOURCE PART PROCESS

pLV[Exp]-hU6 gRNA(AarI)- EFS SV40-NLS/dCas9/ VPR(AarI Mutant):T2A: EGFP-rev(chick U6.3 Promoter gRNA(AarI)) 1 * 1 items

Supplier: MACHEREY-NAGEL

VarioPrep HPLC guard column cartridge (short) VP 15/32 NUCLEODUR C18 ISIS length: 15 mm, ID: 32 mm pack of 1 - compatible with Vari oPrep HPLC column with ID 32 or 40 mm - requires VP guard column holder 32 mm (short version, p/n 718253) 1 * 1 items