12104 Results for: "Trimethylsilyl+trifluoromethanesulphonate&pageNo=17&view=list"

Supplier: Bioss

The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronectin like repeats, a hinge region, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, gelatinase, stomelysin and membrane type MMP subfamilies. All MMPs are synthesized as proenzymes, and most of them are secreted from the cells as proenzymes. Thus, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.MMP17 has been reported to be elevated in several tumor cell lines, and is constituitively produced by some normal cell lines. Treatment of cells with Concanavolin A or the phorbol ester TPA stimulates production of MMP17 in some cell types, and the enzyme can be recovered in cell lysates. Shed forms of MMP17 have also been reported.

Supplier: Bioss

The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronectin like repeats, a hinge region, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, gelatinase, stomelysin and membrane type MMP subfamilies. All MMPs are synthesized as proenzymes, and most of them are secreted from the cells as proenzymes. Thus, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.MMP17 has been reported to be elevated in several tumor cell lines, and is constituitively produced by some normal cell lines. Treatment of cells with Concanavolin A or the phorbol ester TPA stimulates production of MMP17 in some cell types, and the enzyme can be recovered in cell lysates. Shed forms of MMP17 have also been reported.

Supplier: DWK Life Sciences

TISSUE GRINDER 0.3ML MICRO DUAL ALLGLASS 1 * 1 items

Supplier: CUSTOM MADE CHEMICALS LAB

10mg/l each of Ag As Ba Cd Co Cr Cu Hg Li Ni Pb Sb Se Sn Tl V Mo 1 * 100 mL

Supplier: KOEHLER TECHNISCHE PRODUKTEN

transparente Dose, blauer Deckel 1 * 1 items

Supplier: EPPENDORF

Eppendorf epT.I.P.S.® Reloads offer high-precision pipette tips in 'Eppendorf Quality' and 'PCR clean' purity grades. Eco-friendly, cost-effective, and designed for seamless compatibility with Eppendorf Box 2.0, they ensure accuracy and sustainability in labs.

Supplier: HORIBA

These waterproof meters can measure and display up to 11 parameters simultaneously with one single probe. Thanks to their rugged design and their field replaceable sensors they are ideal for outdoor use, for example, when testing ground or surface water. Their compact size and the hand strap enable one-handed operation.

Supplier: CPACHEM

POTASSIUM NITRATE (V) 1 MOL/L ISO 17034 1 * 1 L

Supplier: Lovibond Tintometer

Filter Set 3000 Comp. Gardner (TINT 342000 ) 1 * 1 items

Supplier: NEUBERT VOLUME GLASSWAERE

Kurzschliff, Flachboden 1 * 1 items

Supplier: Bioss

The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronectin like repeats, a hinge region, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, gelatinase, stomelysin and membrane type MMP subfamilies. All MMPs are synthesized as proenzymes, and most of them are secreted from the cells as proenzymes. Thus, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.MMP17 has been reported to be elevated in several tumor cell lines, and is constituitively produced by some normal cell lines. Treatment of cells with Concanavolin A or the phorbol ester TPA stimulates production of MMP17 in some cell types, and the enzyme can be recovered in cell lysates. Shed forms of MMP17 have also been reported.

Supplier: OHAUS

The Defender 5000 series multifunctional bench scales are ideal for numerous applications including production, packaging, inventory and shipping. Durably constructed to withstand harsh environments and equipped with a stainless steel platform, stainless steel frame and a stainless steel (single range models) or aluminium load cell (dual range models). The front mounted D52XW indicator is 304 stainless steel with sand blasted surface treatment, which offers protection to IP 68.

Supplier: WATERS

Column Acquity BEH C18 VanGuard Pre-column 1.7um 2.1 x 5mm 1 * 3 items

Supplier: SARSTEDT

2ml Autoanalyser Sample Cups for Hitachi Analysers (Polystyrene) 38x17mm 1 * 5.000 items

Supplier: Lovibond Tintometer

4/49 I.F.U. Disc (TINT 244900 ) 1 * 1 items

Supplier: Lovibond Tintometer

4/50 I.F.U. Disc (TINT 244700 ) 1 * 1 items

Supplier: OriGene

Recombinant human HSD17B11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. 1 * 100 µG

Supplier: MARKET SOURCE PART PROCESS

POLYMAKER POLYLITE PLA PRO BLAUW 1.75 MM 1 * 1 items

Supplier: DWK Life Sciences

Tube 50ml, round, 34x100mm, borosilicate3.3. 1 * 200 items

Supplier: RPB SAFETY

The RPB PX5 is a battery powered air purifying respirator fan unit which draws in contaminated air from the wearer's immediate vicinity, passing it through internal filters, and supplying the filtered air to an approved RPB loose fitting respirator head top.

Supplier: Portwest

These multi use high visible bodywarmer vests are specially designed for those who will not compromise on style, comfort, protection and performance. These garments are designed to keep warm, dry and visible in all conditions. The 300D Oxford Industry High Visibility provides comprehensive range of single and combination garments in a highly durable and cleverly designed innovative styles.

Supplier: WATERS

Column AccQ-Tag Ultra C18 1.7um 2.1 x 100mm 1 * 1 items

Supplier: DEUTSCH NEUMANN

HOLLOW STOPPERS NAT. RUBB. RED 19/17MM 1 * 100 items

Supplier: NEUBERT VOLUME GLASSWAERE

mit Kurzschliff Rundboden 24 x 2,5 100 mm 36,80 + - 0,10g 1 * 1 items

Supplier: HWS LABORTECHNIK

O-RING 1 * 1 items

Supplier: LGC Standards PROMOCHEM

11-DEOXYCORTISOL (17,21-DIHYDROXYPREGN-4-ENE-3,20-DIONE) 1 * 10 mg

Supplier: Seward (FermionX)

Stomacher® bags are all manufactured from virgin polymer granule extruded into a tube. The only seal is at the base. All bags are batch tested and in-process monitored during manufacturing on Stomacher® machines. Bags are tested against a wide range of parameters that include open-ability, transparency, and flexibility as well as dimensions and performance. Stomacher® bags come in a range of formats to suit all applications.

Supplier: ProSci Inc.

The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: LABORIAL

Innovative interactive worktop for laboratories, cleanrooms and healthcare. A hygienic design based on GMP guidlines which consists of a continuous, tempered glass surface on phenolic resin laminate in which is embedded a touch control screen, to provide an interactive worktop, all supported on a metallic structure. At the same time, it works as a regular worktop and solves the disinfection and contamination problems associated with the use of tablets, notebooks, PCs, keyboards and mouse in cleanrooms and other controlled environments. It allows access to any laboratory software such as electronic notebooks, LIMS, Wikis, analysis software, Office and others, on the laboratory workbench, whilst maintaining an aseptic environment. The interactive worktop can help to reduce traffic, in and out of critical areas in which the use of handheld computer devices are restricted or prohibited.

Supplier: Merck

Monolithic silica technology: A new age in chromatography. Chromolith® columns are based on silica so existing methods can be easily transferred with only minimal investment in new method development work. 'Sol-Gel' technology allows highly porous monolithic rods of silica to be formed. These feature a bimodal pore structure provides a unique combination of macropores and mesopores.