48170 Results for: "Trimethylsilyl+2,2-difluoro-2-(fluorosulphonyl)acetate&pageNo=8"

HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc.) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains stable under both conditions. Besides their critical role in hypoxic response, HIF1s regulates the transcription of genes responsible for angiogenesis, erythropoiesis/iron-metabolism, glucose metabolism, cell proliferation/survival, adipogenesis, carotid body formation, B lymphocyte development and immune reactions.

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lOVIBOND 28 89 412 - Chlorine, pH, liquid reagents 0.02 - 4 mg/l Cl2 / 6.5 - 8.4 pH 1 * 1 items

Supplier: Lovibond

lOVIBOND 28 89 412 - Chlorine, pH, liquid reagents 0.02 - 4 mg/l Cl2 / 6.5 - 8.4 pH 1 * 1 items

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Respiratory Syncytial Virus Nucleoprotein Antibody (4-18) 1 * 100 µl

Supplier: Novus Biologicals

Respiratory Syncytial Virus Nucleoprotein Antibody (4-18) 1 * 100 µl

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Clamping Nut, Suitable for BOLA Globe Stirrer Couplings for shaft O. D. 6,5 + 10 mm and 8 + 10 mm, Cat. No. C 398-08 and C 398-12 1 * 3 items

Supplier: Bohlender

Clamping Nut, Suitable for BOLA Globe Stirrer Couplings for shaft O. D. 6,5 + 10 mm and 8 + 10 mm, Cat. No. C 398-08 and C 398-12 1 * 3 items

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Gas Distributor, Suitable for BOLA Scrubber Adaptors GLS 80 / Scrubber Bottles Vitrum gl45, Cat. No. N 1660-24, N 1662-34, N 1662-44 1 * 5 items

Supplier: Bohlender

Gas Distributor, Suitable for BOLA Scrubber Adaptors GLS 80 / Scrubber Bottles Vitrum gl45, Cat. No. N 1660-24, N 1662-34, N 1662-44 1 * 5 items

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Flexible discharge tube for genius / simplex 2, 5 and 10 ml Coiled, made of FEP, approx. 80 cm length, with handle and recirculation valve made of PTFE. Includes handle and assembly instructions. Not suitable for hydrofluoric acid (HF) 1 * 1 items

Supplier: VITLAB

Flexible discharge tube for genius / simplex 2, 5 and 10 ml Coiled, made of FEP, approx. 80 cm length, with handle and recirculation valve made of PTFE. Includes handle and assembly instructions. Not suitable for hydrofluoric acid (HF) 1 * 1 items

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Anti-CD14 Mouse Monoclonal Antibody [clone: MEM-18] (FITC (Fluorescein Isothiocyanate))

Supplier: Abcam

FITC Mouse monoclonal [MEM-18] to CD14.

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Methyl-2-aminoisonicotinate 98%

Supplier: Apollo Scientific

Methyl-2-aminoisonicotinate 98%

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Methyl-3,4,5-trihydroxybenzoate 98%

Supplier: Apollo Scientific

Methyl-3,4,5-trihydroxybenzoate 98%

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1-Acetyladamantane 98%

Supplier: Apollo Scientific

1-Acetyladamantane 98%

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Furan-3-boronic acid 98%

Supplier: Apollo Scientific

Furan-3-boronic acid 98%

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Safety shoes, lace-up, suXXeed® Offroad, 62743, Heckel

Supplier: UVEX

Metal-free, flexible, lightweight safety shoe made from breathable suede leather upper plus a double-desity PU2D sole, highly slip resistant and resistant to oils and hydrocarbons.

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Anti-Cytokeratin 18 antibody [C-04] (Biotin) 1 * 50 µG

Supplier: Abcam

Anti-Cytokeratin 18 antibody [C-04] (Biotin) 1 * 50 µG

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Cleanroom socks, BCR®

Supplier: BERKSHIRE

These extremely soft and comfortable cleanroom socks are made from 96% microdenier nylon and 4% double covered Lycra, constructed using a special seamless, no-run and non-ravel technique. The micro denier technology provides the sock with superior cool feeling and comfort. Due to the enhanced wicking function, contact discomfort associated with wearing regular cotton or polyester socks is greatly reduced.