Order Entry
Northern Ireland
ContactUsLinkComponent
 

10981 Results for: "Tetramethylammonium+hydrogen+sulphate&pageNo=21"

Fluo-4 AM

Fluo-4 AM

Supplier: Biotium

Membrane-permeant form of Fluo-4 calcium indicator.

Expand 1 Items
Loading...
Pipette tips, Standard

Pipette tips, Standard

Supplier: Brand

These tips are manufactured under cleanroom conditions and are automatically packaged to ensure that the tips are consistently free from contamination.

    
Expand 1 Items
Loading...
DNA ladders, GeneRuler™ and O'GeneRuler™

DNA ladders, GeneRuler™ and O'GeneRuler™

Supplier: Thermo Fisher Scientific

Thermo Scientific™ GeneRuler™ and O'GeneRuler™ DNA ladders are mixtures of chromatography-purified individual DNA fragments. The GeneRuler™ line includes the most popular ladders, such as the 100 bp and 1 kb DNA Ladder. GeneRuler™ DNA ladders are available in two formats: Conventional (provided in TE buffer) and a ready-to-use format (premixed with 6X DNA Loading Dye which contains bromophenol blue and xylene cyanol FF). O'GeneRuler™ DNA ladders are another ready-to-use version of GeneRuler™ DNA ladders that are premixed with 6X Orange DNA Loading Dye.

Expand 1 Items
Loading...
Anti-ATP6V0B Rabbit Polyclonal Antibody

Anti-ATP6V0B Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.

Expand 1 Items
Loading...

Anti-HRP2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Supplier: Bioss

Hepatoma Derived Growth Factor (HDGF) is the original member of a family of polypeptides designated HDGF-related proteins (HRPs). HDGF was initially characterised as a secreted mitogen from the Huh-7 human hepatoma cell line. This nuclear targeted vascular smooth muscle cell mitogen (VSM) is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. During development, HDGF expression is high in the nucleus and cytoplasm of smooth muscle and endothelial cells. The HRP (HDGF related proteins) family contains four proteins, HRP-1, HRP-2, HRP-3 and HRP-4. HRP-1 and HRP-4 are only expressed in testis while HRP-2 is widely expressed in different tissues. HRP-3 can solely be found in the nervous system. Specifically it is strongly expressed in bulbus, olfactorius, piriform cotrex and amygdala complex while HRP-2 in brain is located in the the thalamus, prefrontal and parietal cortex, neurohypophysis, and the cerebellum. In the central nervous system, HRP proteins are play a role in neuron proliferation and cell survival.

Expand 1 Items
Loading...
High purity qualitative filter paper

High purity qualitative filter paper

Supplier: Ahlstrom-Munksjö

These qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers cover a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.

Expand 1 Items
Loading...

TSKgel® gel filtration columns, PW-type

Supplier: TOSOH BIOSCIENCE

These columns are designed for GFC of water soluble organic polymers, polysaccharides, oligosaccharides, DNA and RNA. They are based on a hydrophilic polymethacrylate matrix, which is stable from pH 2 to 12 and in aqueous eluents with up to 50% polar organic solvent.

Expand 1 Items
Loading...
Precision balances, Cubis® II high capacity

Precision balances, Cubis® II high capacity

Supplier: Sartorius Balances

The Cubis® II range has a modular design that to allows the customer to choose the components that suit the application area that is of interest. For the customer, this configurable concept delivers quality weighing, together with a high degree of flexibility, without having to invest in expensive equipment that has features that may never be required.

Expand 16 Items
Loading...
TSX™ Core Ultra-Low Temperature Freezers, −86 °C

TSX™ Core Ultra-Low Temperature Freezers, −86 °C

Supplier: Thermo Scientific

TSX™ core series is engineered for reliability and designed for everyday use. When choosing a ULT freezer, protecting your valuable samples is the top priority.  The Thermo Scientific™ TSX™ core series ULT freezers are designed with this in mind, offering reliable sample protection even in the busiest laboratory environments.

Expand 2 Items
Loading...
Ultra low temperature freezers, with 4 inner doors, –40 °C, TDE series

Ultra low temperature freezers, with 4 inner doors, –40 °C, TDE series

Supplier: Thermo Scientific

Thermo Scientific™ TDE Series ‒40 °C ultra-low temperature freezers, powered by H-drive, feature three upright models, maximizing storage capacity from 40000 up to 60000 2 ml vials. The TDE Series is a sustainable and reliable solution with ultimate sample security and operational savings for every laboratory.

    
Expand 2 Items
Loading...
Cubis® II MCE Ultra-High Resolution Semi-Micro Balances

Cubis® II MCE Ultra-High Resolution Semi-Micro Balances

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.

Expand 12 Items
Loading...
Ultra low temperature freezers, with 5 inner doors, –86 °C, TDE series

Ultra low temperature freezers, with 5 inner doors, –86 °C, TDE series

Supplier: Thermo Scientific

Thermo Scientific™ TDE Series ultra-low temperature freezers, powered by H-drive, feature four upright models with 5 Inner doors, maximizing storage capacity from 30000 up to 60000 2 ml vials. The TDE Series is a sustainable and reliable solution with ultimate sample security and operational savings for every lab. Sustainability features include natural refrigerants and water-blown foam, compliant with many sustainability standards.

Expand 2 Items
Loading...

Anti-FGFR2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Supplier: Bioss

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. FGFR2 signaling is down-regulated by ubiquitination, internalisation and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalisation and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1.

Expand 1 Items
Loading...

Anti-C11orf24 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Supplier: Bioss

C11orf24, also known as DM4E3, is a 449 amino acid single-pass type I membrane protein that is expressed in brain, lung, skeletal muscle, kidney, spleen, prostate, testis, ovary and small intestine, with highest expression in heart, placenta, liver, pancreas and colon, and low expression in thymus and leukocytes. C11orf24 is encoded by a gene located on human chromosome 11, which consists of approximately 135 million base pairs and 1400 genes. Chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumours, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Expand 1 Items
Loading...
Precision balances, Cubis II series

Precision balances, Cubis II series

Supplier: Sartorius Balances

The Cubis® II range has a modular design that to allows the customer to choose the components that suit the application area that is of interest. For the customer, this configurable concept delivers quality weighing, together with a high degree of flexibility, without having to invest in expensive equipment that has features that may never be required.

Expand 44 Items
Loading...
Trousers, KX3 Ripstop T802

Trousers, KX3 Ripstop T802

Supplier: Portwest

Contemporary work trouser made from highly durable ripstop fabric that stretches as you move. Subtle articulation on the knees allow for increased freedom of movement and a high rise back waistband ensures protection in all working positions. Packed with functionality including pre-bent knees, a crotch gusset, two tier knee pad pockets and an adjustable leg length for added convenience.

Expand 1 Items
Loading...
Thermal imager, testo 865s

Thermal imager, testo 865s

Supplier: Testo

The testo 865s thermal imager offers professional technology and concentrates on functions which are needed in a contractor's daily work. The user-friendly thermal imager, optimized for fast and efficient work. With the testo ScaleAssist functions ensuring optimum setting of the thermal image scale for building thermography and the IFOV warner making sure to avoid measurement errors, always generate the perfect infrared image. This combines all the important properties required for high-quality thermographic measurement – it is accurate, robust, fast and reliable. The case supplied with the thermal imager means it can be conveniently transported, so it is always there for you when needed.

Expand 1 Items
Loading...
Digital microscopes, Emspira 3

Digital microscopes, Emspira 3

Supplier: LEICA MICROSYSTEMS

Emspira 3 digital microscope empowers users to streamline inspection processes, cover inspection needs flexibly, and work with confidence. An ideal partner for manipulation, quality control, inspection and research applications.

Expand 3 Items
Loading...
Digital Fluorescence Inverted Microscope for Advanced Cell Culture Experiments, MATEO FL

Digital Fluorescence Inverted Microscope for Advanced Cell Culture Experiments, MATEO FL

Supplier: LEICA MICROSYSTEMS

Reliable, reproducible, advanced cell checks. Make your cell culture experiments more reliable and consistent with AI-powered algorithms and analysis.

Expand 7 Items
Loading...
Analytical balances, Cubis® II

Analytical balances, Cubis® II

Supplier: Sartorius Balances

The Cubis® II range has a modular design that to allows the customer to choose the components that suit the application area that is of interest. For the customer, this configurable concept delivers quality weighing, together with a high degree of flexibility, without having to invest in expensive equipment that has features that may never be required.

Expand 21 Items
Loading...
High purity qualitative filter paper

High purity qualitative filter paper

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö’s qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers covers a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.

Expand 1 Items
Loading...
DNA cloning kits, Gibson Assembly® HiFi 1 step kit

DNA cloning kits, Gibson Assembly® HiFi 1 step kit

Supplier: SGI - DNA Synthetic Genomics

The Gibson Assembly® HiFi 1 Step Kit provides a simple and effective method to seamlessly construct synthetic genes, genetic pathways, as well as entire genomes. This method allows researchers to achieve complex assembly of large DNA constructs, with multiple inserts, in 1 hour.

Expand 3 Items
Loading...
Antibody labelling kits, Mix-n-Stain™ CF™ Dye

Antibody labelling kits, Mix-n-Stain™ CF™ Dye

Supplier: Biotium

Label your antibody with one of our superior CF® Dyes in 30 minutes without a purification step. Labelling tolerates many common buffer components including BSA and ascites.

Expand 1 Items
Loading...
VWR®, Dehydrated culture media, granulated

VWR®, Dehydrated culture media, granulated

Supplier: VWR Chemicals

VWR® dehydrated culture media that has been granulated offers both convenience and safety benefits. The correct dissolution of culture media is critical to achieving the best performance. Granulated culture media saves time in the preparation of ready to use culture media. In addition, granulation reduces dust generation, so handling the product is more pleasant and safer for the user, making it a much cleaner and safer working environment.

Expand 1 Items
Loading...
Work Trousers, Detachable Holster Pocket, DX4™, DX440

Work Trousers, Detachable Holster Pocket, DX4™, DX440

Supplier: Portwest

The DX4 holster trouser is ergonomically designed and uses the targeted placement of dynamic 4X stretch fabrics to give maximum range of movement when working. The trouser features a high-rise back waistband with side elastication, ensuring protection in all working positions.

Expand 1 Items
Loading...
VWR®, Accessories for Carboys, Versatile Caps, Adapters, Connectors and Spigots

VWR®, Accessories for Carboys, Versatile Caps, Adapters, Connectors and Spigots

Supplier: VWR Collection

VWR® has expanded the VWR® carboy features and benefits by offering the Versatile Cap, Versatile Barb and state-of-the-art Spigot technology. These three components complement a wide array of applications supported by the VWR® Carboy. The leakproof cap insert with replaceable gasket enable users to quickly change the top connector of each carboy to match the application needs. Versatile Cap is stackable and is offered in both 83 mm (compatible with most industry carboys) and a 120 mm extra wide-mouth version that fits exclusively on VWR® 20 L and 40 L extra wide mouth carboys. To see homogenisation of solutions, closed adapter inserts with a clear window are available. Quick connect options are also a part of the many capabilities of this Versatile Cap technology. This includes quick-connect port combinations of two, three, and four. For bottom tubulation, Versatile Barb is used to replace the spigot and support flexibility in drainage, connection to a pump or automated equipment, or connection to a filling bell. Sanitary fitting connector is also available in order to enable the carboy to be used as a supply reservoir to a larger system.

Expand 1 Items
Loading...
Eppendorf twin.tec® PCR Plates 96-well, 150 µl

Eppendorf twin.tec® PCR Plates 96-well, 150 µl

Supplier: EPPENDORF

Eppendorf's twin.tec® 96-well, 150 µl PCR Plates feature a polycarbonate frame and thin-walled polypropylene wells ensuring optimal heat transfer and high rigidity. The SafeCode variants enhance sample identification, while the BioBased options, manufactured using renewable resources, provide an eco-friendly alternative without compromising performance.

    
Expand 1 Items
Loading...
VWR® M9 UV/Visible Spectrophotometer

VWR® M9 UV/Visible Spectrophotometer

Supplier: VWR Collection

The M9 UV/Vis Spectrophotometer is a double beam UV/Vis spectrophotometer with a variable spectral bandwidth for routine and advanced applications.

Expand 1 Items
Loading...
Anti-TRIM21 Rabbit Polyclonal Antibody

Anti-TRIM21 Rabbit Polyclonal Antibody

Supplier: Bioss

E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr-187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2.

Expand 1 Items
Loading...
High purity hardened qualitative filter paper

High purity hardened qualitative filter paper

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö’s qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers covers a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions. High Purity hardened filter papers grades 1288 to 1291 are also produced from cellulose with an alpha content of nearly 100% resulting in an ash content of <0,1%.

Expand 1 Items
Loading...
Recommended for You