5059 Results for: "Taurodeoxycholic+acid+sodium+salt&pageNo=65"

Supplier: Bioss

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD9 is a non-ATPase subunit of the 19S regulator.

Supplier: Bioss

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Supplier: Bioss

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Supplier: THERMO MATRIX TECHNOLOGIES

Permanently attached, laser-etched 2D barcodes on the bottom of each tube allow you to scan and decode tubes at once without removing them from the rack and allow data to be associated with each tube.

Supplier: Spectrum Laboratories

Hollow fibre filter modules are particularly useful in tangential flow filtration because processes can easily be scaled-up from small volume applications to full-scale production.

Supplier: Greisinger

Pure measurement with a focus on precision, speed and reliability packaged in a compact housing distinguish an impressive price/performance ratio.

Supplier: ISERA

HPLC column of the ISAspher line guarantee the highest possible reliability in a wide range of applications.

Supplier: Bioss

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.

Supplier: Bioss

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.

Supplier: Brady

Work smarter. Label larger with the M511. Print bigger, clearer messages. Go edge to edge. Design and print on the fly, or a PC. Plus, share files, import data and connect up to 5 users simultaneously.

Supplier: VWR Collection

Complete kits that, together with the appropriate balance, allow the user to calculate the density of liquids (such as beverages) or non absorbent solids (rocks, polymers, gems, glass, metals etc). The density wizard function is already included as a built-in function of the balance (except for SE models: 611-2605, 611-2606, 611-2607, 611-3236, 611-3246, 611-3299, 611-3344). Density kits are not designed for use with moisture analysers. Both kits contain similar items, the difference is the balance cone attachment:

Supplier: VWR Collection

INTERIOR LIGHTING FOR IL 240/400/750CR 1 * 1 items

Supplier: 3M

Designed for versatility, 3M™ double coated GPT-020F tape is a transparent, 200 µm thick, modified solventless acrylic adhesive with a white printed PP filmic liner. This tape combines a high level of peel and shear performance, enabling high adhesion to a wide variety of substrates both to high and some low surafce energy substrates.

Supplier: NEW PIG

Eight layers of 100% PP are thermally bonded to make PIG Mat exceptionally strong; won't rip, tear or fray even when saturated.

Supplier: Thermo Fisher Scientific

Thermo Scientific™ Maxima™ H Minus cDNA Synthesis Master Mix provides all cDNA synthesis reaction components in a convenient one-tube master mix. It is optimised for highly efficient cDNA synthesis for two-step quantitative RT-PCR (RT-qPCR) applications.

Supplier: Jallatte

Anti-static ankle boots made from full grain water repellent leather upper, Gore-Tex® Performance lining and Kompact Vibram® sole (fuil and oil resistant; contact heat resistant up to 300 °C HRO); with padded tongue and ergonomic collar. Suitable for off-shore and construction.

Supplier: Brady

Work smarter. Label larger with the M511. Print bigger, clearer messages. Go edge to edge. Design and print on the fly, or a PC. Plus, share files, import data and connect up to 5 users simultaneously.

Supplier: Bioss

MD1 is a 28 kDa molecule that is associated at the cell surface with RP105 (CD180). RP105 is a leucine-rich repeat (LRR) molecule that is expressed on B lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis. LRR proteins, such as Toll receptors, have a role in innate immunity. MD1 is primarily expressed by B cells, dendritic cells and monocytes, and promotes the recognition of, and subsequent signaling by LPS in the innate immune system. MD1 does not have any homology to other molecules. MD1 when expressed alone behaves as a secretory protein. Expression of MD1 in a cell increases the expression of RP105.

Supplier: Bioss

Chromosome 3 is made up of about 214 million bases encoding over 1100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumour suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. The LOC285346 gene product has been provisionally designated LOC285346 pending further characterisation.

Supplier: Bioss

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.

Supplier: Biosensis

This antibody is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling.

Supplier: Thermo Fisher Scientific

Natural tubes are made from 100% virgin PP to help ensure maximum clarity for biological-based work.

Supplier: Jallatte

Metal-free boots made from full grain water repellent leather upper, 3D lining and Kompact Vibram® sole (fuil and oil resistant; contact heat resistant up to 300 °C HRO); with padded tongue, ergonomic collar and anti-abrasion PU scuff cap.

Supplier: bimos

In sensitive ESD work areas in the high-tech industry, first-class equipment is essential to provide reliable protection against electrostatic discharge. The ESD Texon fulfils the strict requirements of the European ESD standard EN 61340-5-1 and therefore offers maximum safety. The chair also makes a clear statement with its ergonomic design and high level of comfort.

Supplier: Avantor Fluid Handling

Masterflex Door Assembly 1 * 1 items

Supplier: Avantor Fluid Handling

Ismatec Rol Hd Ms/Ca-3/06 Reglo Ertte 1 * 1 items

Supplier: NEW PIG

PIG Blue is the most absorbent mat. Maximum absorbency soaks up more so you use less on big spills and high-volume leaks.

Supplier: NEW PIG

Hi-viz spill absorbents alert workers to slip hazards while cleaning up leaks.

Supplier: OMNIFIT

EZ columns are designed to suit the majority of standard laboratory chromatography applications. They are ideal for aqueous systems and compatible with solvents used in common liquid chromatography applications such as protein purification.

Supplier: UVEX

These light and comfortable, sports-style safety spectacles feature a wide field of vision with a contoured lens. They offer a good level of eye coverage and fit all facial shapes including narrower faces, which enables a standardisation of the range.