145762 Results for: "Sodium+hydroxide&pageNo=10&view=list"

Supplier: TOSOH BIOSCIENCE

TSKgel® SW size exclusion columns are widely used for aqueous analysis and isolation of proteins, antibodies, enzymes, nucleic acids and other biological macromolecules.

Supplier: LGC Standards PROMOCHEM

ESTRIOL IMP. F (EP):16-EPI-ESTRIOL 1 * 100 mg

Supplier: HAAKE

VISCOTESTER IQ PACK FOR PASTES TM-PE-P 1 * 1 SET

Supplier: HIRSCHMANN

VOL.FLASK 20ML NS10/19 AMBER POLYSTOPP A 1 * 1 items

Supplier: USA SCIENTIFIC PLASTICS

Tip pipette 10µl hinged rack certified sterile 1 * 960 items

Supplier: witeg Labortechnik

WHM12019,Aℓ-case Heating Mantles with Controller, 450℃, for 10,000ml Spherical flask(DU) 1 * 1 items

Supplier: VITLAB

Volumetric flask, PP, class B, with screw cap, PP, 100 mL 1 * 2 items

Supplier: BD Medical

Syringe 10ml 20Gx1 inch Luer-Lok 1 * 400 items

Supplier: DWK Life Sciences

Valve discharge for DURAN Group dispenser PRO 2,5/5/10ml (PFA/Borosilicate glass/Platin-Iridium) 1 * 1 items

Supplier: NEUBERT VOLUME GLASSWAERE

flat bottom glass 36x1,4x120mm 54mm with ring mark fused straight bottom ca.45ml ring mark mark at 54+-0,5mm inside measured straight bottom straight rim fused (pour point glass ) from Boro 3.3 1 * 1 items

Supplier: ProSci Inc.

This antibody is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound protein. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product C4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival. C4d antibody, combined with antibody to C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Supplier: ProSci Inc.

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells By similarity. Phosphorylates heat shock factor protein 4 (HSF4). /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it./Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. Required for stress-induced neuronal apoptosis and the pathogenesis of glutamate excitotoxicity

Supplier: Hach

Robust and intuitive portable meters, instilling confidence in reporting and managing your results.

Supplier: EPPENDORF

Eppendorf epT.I.P.S.® BioBased Reloads in 'Biopur' grade innovate with cutting edge eco-friendly design. The tips are made from 90% plant-based material in a reloadable format. They ensure precision and purity, and are ideal for sensitive applications prioritising environmental responsibility.

Supplier: IKA

TWISTER is a universal and compact mixing device with magnetic drive. In the default version, TWISTER is a powerful single-position magnetic stirrer for mixing up to 5 litres at a maximum speed of 3000 min⁻¹ and a viscosity of up to 500 mPa·s. By connecting additional TWISTER stirring units (available as accessories, IKAA20112621), TWISTER can be expanded to a multi-position magnetic stirrer with up to 30 stirring positions. The stirring positions can be controlled either separately or simultaneously (leader-follower principle).

Supplier: DUPERTHAL

Exhaust air monitor optional with ventilator: Easy ventilation and monitoring of the venting system for safety cabinets. A sensor monitors the air flow speed/stream and gives a visual or audible signal if the value drops below the set-point value. The complete exhaust monitoring unit is supplied pre-assembled (ready to plug in) and is placed directly on the cabinet. The set-point value for the air stream flow rate is preset in the factory and can be individually adjusted by the pressure difference socket. In addition to the volumetric flow rate the power supply is also monitored. The system includes two floating contacts (24 V/2 A) for signal transmission to an external control room. Internal storage accumulator supplies the monitoring systems for 4 hours in the event of a power failure, display with easy fault indication and enables permanent monitoring according to DIN EN 1946-7. The housing is made from powder-coated sheet steel, silver pearl glimmer.

Supplier: Thermo Fisher Scientific

Thermo Scientific Pierce EDC is a carboxyl- and amine-reactive zero-length crosslinker. EDC reacts with a carboxyl group first and forms an amine-reactive O-acylisourea intermediate that quickly reacts with an amino group to form an amide bond with release of an isourea by-product. The intermediate is unstable in aqueous solutions and so two-step conjugation procedures rely on N-hydroxysuccinimide (NHS) for stabilization. Failure to react with an amine will result in hydrolysis of the intermediate, regeneration of the carboxyl, and release of an N-substituted urea. A side reaction is the formation of an N-acylurea, which is usually restricted to carboxyls located in hydrophobic regions of proteins.

Supplier: witeg Labortechnik

Heating Mantles WHM, for beakers 10.000 ml,without integrated power controller, temp. range 450C,1400 W, power supply 230 V 1 * 1 items

Supplier: Greiner Bio-One

PIPET 5ML SER. PLAS/PLAS TRIPLE PACKING 1 * 100 items

Supplier: MP Biomedicals

Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products and the extremely viscous higher molecular weights would be the products in the range of 70,000-150,000.
It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Other uses for poly-lysine have been reported as well:
• Conjugation to methotrexate for increased drug transport.
• Microencapsulation of islets.
• Use in simple reproducible procedure for chromosomal preparations from a variety of tissues.
• Immobilation of living cells in biocompatible semipermeable microcapsules.
• In the preparation of polycationic beads.
• Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Supplier: ProSci Inc.

IL-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of Toll/IL-1 receptor (TIR) family members. The cytoplasmic domains of TIR proteins interact with the adapter protein, MyD88. MyD88 then recruits IRAKs (IRAK-1, -2, and M), which in turn interact with other adapter molecules, such as TRAF6 to activate NF-κB and MAPK pathways. Recently, a new member of this family, IRAK-4 has been identified. IRAK-4 may act as an upstream activator of IRAK-1. IRAK-4 is important for LPS activation of TLRS. Mice lacking IRAK-4 are resistant to lethal doses of LPS and are also severely impaired in their responses to viral and bacterial challenges (4, 5). IRAK4, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK4 has auto- and cross-phosphorylation kinase activity and has been shown to phosphorylate and activate IRAK1. Additionally, IRAK4 interacts with IRAK1 and TRAF6 in an IL-1-dependent manner, and overexpression of IRAK4 can activate NF-kappaB as well as mitogen-activated protein (MAP) kinase pathways. IRAK4 (-/-) mice are resistant to a lethal dose of lipopolysaccharide and are severely impaired in their responses to viral and bacterial challenges. At least two mRNA transcripts have been reported: 3.0- and 4.4-kb. IRAK4, also referrred to as NY-REN-64, was first identified as an anitgen in a screen of renal tumors.

Supplier: Thermo Fisher Scientific

Pierce™ Boronic acid resin enables ribonucleotide and oligonucleotide RNA isolation.

Supplier: MARIENFELD

Plate, staining ,12 place ,79 x 63 x 4 mm dimension,made of pressed glass,cavity 16mm, diameter 2mm depth 1 * 15 items

Supplier: Corning

SQUARE BOTTLE 500ML HDPE NA H147 Ø29, 10MG SODIUM THIO, LABEL WH & TAMPER EVIDENT HINGED PLUG RE, IONISED 1 * 100 items

Supplier: HIRSCHMANN

Flask volumetric, capacity 20ml, USP individual certificate, class A, graduated, conformity certified. 1 * 1 items

Supplier: UVEX

BRILLE I-WORKS i-5 Zertifiziert nach EN 166 (persönlicher Augenschutz) und EN 170 (UV-Schutz-Filter) Kennzeichnung: W 166 FT CE – 2C-1,2 W1 FTKN CE UV400 – 100 % Schutz vor gefährlicher UVA- und UVB-Strahlung bis 400 nm 1 * 1 items

Supplier: MEMMERT

The range has natural and forced convection models with a temperature range up to 80 °C. There is a choice of two different displays, SingleDISPLAY or TwinDISPLAY depending on the application.

Supplier: HUBER

Circulating bath thermostats with baths made from stainless steel are simple to use and suitable for many applications such as: sample temperature control, analysis, material testing or checking food. The units offer high temperature stability and are fitted with over-temperature and low level protection suitable for use with flammable fluids. A powerful pressure/suction pump ensures optimum circulation and temperature homogenity in the bath and also allows temperature control of external applications using a pump adapter (accessory). There is a range of optional accessories including inserts, variable adjustable platforms, bath covers, probes as well as tubing, temperature-control fluids and various adapters, please see www.vwr.com for details.

Supplier: Thermo Fisher Scientific

In order to maintain cellular viability during the freezing process, certain cells such as protist, mammalian, and plant cells require precise control of the freezing rate in order to minimize the detrimental effects of undercooling and the heat liberated during the phase change process from water to ice. The Thermo Scientific™ CryoMed™ Controlled-Rate Freezers (CRFs) are designed with reliability, protection, and data traceability in mind for sample preparation and GMP production needs.

Supplier: Thermo Fisher Scientific

Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.