14995 Results for: "Sodium+chlorate"

Supplier: G-Biosciences

L-lactate is produced from pyruvate by the enzyme Lacate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. S 1 * 50 g

Supplier: G-Biosciences

L-lactate is produced from pyruvate by the enzyme Lacate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. S 1 * 10 g

Supplier: MP Biomedicals

USP GRADE. 1 * 100 g

Supplier: MP Biomedicals

USP GRADE. 1 * 500 g

Supplier: G-Biosciences

L-lactate is produced from pyruvate by the enzyme Lacate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. S 1 * 5 g

Supplier: MP Biomedicals

Photoinitiator of polymerization useful in either acid or alkaline buffer systems. 1 * 5 g

Supplier: MP Biomedicals

Potency:~900 µ g/mg Crystalline Topoisomerase II inhibitor 1 * 1 g

Supplier: G-Biosciences

molecular grade, concentrated running buffer for dna and rna electrophoresis. 1 * 250 mL

Supplier: G-Biosciences

Carbonyl groups, including aldehydes, ketones and glyoxals, react with amines to form Schiff base intermediates that are in equilibr ium with their free forms. The labile Schiff’s base interaction can be stabilized by chemical reduction. 1 * 2.000 mg

Supplier: MP Biomedicals

Purity: >98% 1 * 100 g

Supplier: ProSci Inc.

Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.

Supplier: LGC Standards PROMOCHEM

5-(Difluoromethoxy)-2-[[(3 ,4-dimethoxypyridin-2-yl)methyl]sulphanyl]-1H-benzimidazole 1 * 100 mg

Supplier: Cayman Chemical

Cefazolin is a broad-spectrum, first-generation cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram -negative bacteria.{25759} It inhibits bacterial cell wall synthesis, causing growth to cease without lysis (5 µg/ml 1 * 1 g

Supplier: G-Biosciences

Mode of action and Anti-microbial spectrum: Ampicillin is an inhibitor of bacterial cell wall synthesis which acts by inhibiting the cross-linking of peptidoglycan. It is used in the selection of antibiotic cell hybrids, and has a high rate of actio 1 * 10 g

Supplier: MP Biomedicals

Cell Culture Reagent Anhydrous 1 * 100 g

Supplier: Cayman Chemical

Cefazolin is a broad-spectrum, first-generation cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram -negative bacteria.{25759} It inhibits bacterial cell wall synthesis, causing growth to cease without lysis (5 µg/ml 1 * 100 mg

Supplier: MP Biomedicals

Purity: 99% Anionic detergent used to solubilize proteins prior to electrophoresis. 1 * 25 g

Supplier: G-Biosciences

Mode of action and Anti-microbial spectrum: Ampicillin is an inhibitor of bacterial cell wall synthesis which acts by inhibiting the cross-linking of peptidoglycan. It is used in the selection of antibiotic cell hybrids, and has a high rate of actio 1 * 500 g/mol

Supplier: PanReac AppliChem

SDS, ACS 1 * 250 g

Supplier: PanReac AppliChem

SDS, ACS 1 * 5 kg

Supplier: ProSci Inc.

General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase. /General protein kinase capable of phosphorylating several known proteins. /IGF-1 leads to the activation of AKT3, which may play a role in regulating cell survival. Capable of phosphorylating several known proteins. Truncated isoform 2/PKB gamma 1 without the second serine phosphorylation site could still be stimulated but to a lesser extent.

Supplier: ProSci Inc.

Principal Names: SnoN; SNO; SKI-like; Ski-related Oncogene; SnoA; SKIL Official Gene Symbol- SKIL Gen Bank Accession Number- NP_005405 Gene ID- 6498(Human) 20482 (mouse)Gene Map Locus- 3q26 (human) SnoN, an 80 kDa protein, is a member of ski family of nuclear proto-oncogenes involved in regulation of cellular transformation and differentiation. Primarily expressed in two isoforms, SnoN is localized in cytoplasm in normal tissues and non-tumorigenic primary epithelial cells. In cancer tissues or cells, SnoN is exclusively localized in the nucleus. It plays a vital role in inhibition of cell cycle arrest induced by TGF-. Upon morphological differentiation or cell-cycle arrest, SnoN translocates into the nucleus, binds to Smad2, Smad3, and Smad4 on TGF- -responsive promoters and represses their ability to activate expression of TGF- target genes. It has also been found to mediate transcriptional repression of thyroid hormone receptor, Mad and pRb. Increased expression of SnoN has been detected in many human tumor cell lines suggesting a clinical significance.

Supplier: Cytiva

rProtein A Sepharose™ 4 Fast Flow is a well established antibody affinity medium is designed for the purification of monoclonal and polyclonal antibodies based on Sepharose™ Fast Flow platform. The recombinant protein A is produced in E.coli and engineered for an oriented coupling to giving a matrix with enhanced binding capacity. The epoxy-based coupling ensures low ligand leakage. The specificity of the recombinant protein A for the Fc region of IgG is similar to native protein A and provides excellent purification in one step. The high capacity, low ligand leakage and a well established base matrix makes rProtein A Sepharose™ Fast Flow ideal for purification of monoclonal antibodies at both laboratory and process scale.

Supplier: Cayman Chemical

Cefazolin is a broad-spectrum, first-generation cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram -negative bacteria.{25759} It inhibits bacterial cell wall synthesis, causing growth to cease without lysis (5 µg/ml 1 * 250 mg

Supplier: Cayman Chemical

Cefazolin is a broad-spectrum, first-generation cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram -negative bacteria.{25759} It inhibits bacterial cell wall synthesis, causing growth to cease without lysis (5 µg/ml 1 * 500 mg

Supplier: Merck Millipore (Calbiochem‎)

Sialyl Lewis X 1 * 1 mg

Supplier: Merck Millipore (Calbiochem‎)

Sialyl Lewis X 1 * 5 mg

Supplier: Cytiva

MabSelect SuRe™ is composed of a rigid, high-flow agarose matrix and alkali-tolerant rProtein A ligand. The ligand has been engineered to provide greater stability than conventional protein A-based media in the alkaline conditions used in CIP protocols. This enhanced alkali stability improves process economy and product quality.

Supplier: ProSci Inc.

FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Variant 1 (isoform a) encodes the longest transcript. Variant 2 (isoform b) contains an alternate exon, which results in an early stop codon, compared to variant 1. Isoform b has a shorter C-terminus when compared to isoform a. Mutations in this gene are the most common cause of Fanconi anemia.

Supplier: ProSci Inc.

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by Chk2 gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Three transcript variants encoding different isoforms have been found for this gene.