Supplier: HONEYWELL SAFETY

GLOVE DEEP BLUE WINTER GAUGE 13 S.9 1 * 1 PAIR

Supplier: witeg Labortechnik

TUBING DISCHARGE FOR LABMAX 100ML 1 * 1 items

Supplier: EPPENDORF

Eppendorf ep Dualfilter T.I.P.S.® SealMax® Racks provide advanced self-sealing pipette tips in 'PCR clean and Sterile' grade, featuring unique two-phase filters for unparalleled protection against contamination in sensitive lab applications.

Supplier: Portwest

The DX4 work trouser is ergonomically designed and uses the targeted placement of dynamic 4X stretch fabrics to give maximum range of movement when working. Triple stitching throughout for maximum durability.

Supplier: ProSci Inc.

Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö’s qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers covers a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions. High Purity hardened filter papers grades 1288 to 1291 are also produced from cellulose with an alpha content of nearly 100% resulting in an ash content of <0,1%.

Supplier: Labcon

ProtectR® tube is the only container closure system engineered to be CO₂ resistant and stop costly damage to molecular and cellular solutions when using dry ice. Made of durable, high-quality materials and fitted with an air-tight cap, ProtectR® Tubes form a protective barrier impermeable to CO₂, keeping the sample pH stable and preventing acidification.

Supplier: SONICS MATERIALS

3 mm (1/8 ) Stepped Micro Tip for multielement probes 1 * 1 items

Supplier: Amarell

ALCOHOLOMETER 90-100:0.1%VOL W/THER DKD 1 * 1 items

Supplier: witeg Labortechnik

Flask for collecting nitrogen 25ml,with cylindrical hook, 120x32mm, st14/23,acc. to schlenk, null

Supplier: MP Biomedicals

p nitrophenol is the substrate of choice for use with alkaline phosphatase in ELISA procedures. This substrate produces a soluble end product that is yellow in color and can be read spectrophotometrically at 405 nm. The pNPP reaction may be stopped with 3 M NaOH and read at 405 nm.

Supplier: witeg Labortechnik

Flask for collecting nitrogen 25ml, with cylindrical stopcock,120x32mm, st14/23,acc. to schlenk, null

Supplier: GLASWARENFABRIK KARL HECHT

CENTRIFUGE TUBE BORO 100X24/25MM UNGRAD 1 * 100 items

Supplier: witeg Labortechnik

Flask for collecting 25ml,with cylindrical stopcock, 120x32mmmm, acc. to schlenk, null

Supplier: MACHEREY-NAGEL

NanOx N pack of 30g decomposition reagent with spoon and 25g compensation reagent with spoon NANOCOLOR. 1 * 30 g

Supplier: HONEYWELL SAFETY

GLOVE DEEP BLUE WINTER GAUGE 13 S.11 1 * 1 PAIR

Supplier: CUSTOM MADE CHEMICALS LAB

D-(+)-Glucose CAS: 50-99-7 EC:200-075-1 CRM, ISO 17034 and ISO 17025 Conservation 24 months. Store under normal laboratory conditions, at temperatures between 15C to 25C 1 * 250 mg

Supplier: CUSTOM MADE CHEMICALS LAB

Calcium Carbonate - Certified Reference Material for standardization of volumetric solutions CRM, ISO 17034 and ISO 17025 Conservation 60 months. Store under normal laboratory conditions, at temperatures between 15C to 25C 1 * 50 g

Supplier: ProSci Inc.

RAC-alpha serine/threonine-protein kinase (AKT1) is also known PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt and RAC-PK-alpha, which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and RAC subfamily and is expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity. Phosphorylation of GSK3 isoforms by AKT is also thought to be one mechanism by which cell proliferation is driven. AKT regulates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase).

Supplier: witeg Labortechnik

Flask for collecting 25ml, with cylindrical needle valve,120x32mmmm, acc. to schlenk, null

Supplier: witeg Labortechnik

Flask for collecting 25ml, with cylindrical hook,120x32mmmm, acc. to schlenk, null

Supplier: PFEIFFER VACUUM

HISCROLL 6 STANDARD 1 * 1 items

Supplier: Kautex

Screw cap pe black with pull-off ring 60 1 * 1 items

Supplier: witeg Labortechnik

Flask, 25ml, ST19/26, pear shaped, outer diameter 43mm, height 95mm, borosilicate glass 3.3 1 * 1 items

Supplier: EPPENDORF

Eppendorf epT.I.P.S.® Bulk packs offer a practical, high-volume solution with 'Eppendorf Quality' pipette tips, ensuring precise and reliable measurements for various lab applications, packaged economically for high-throughput settings.

Supplier: MERCK PRODUCTION CHEMICALS

Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate), EMPROVE® ESSENTIAL Ph. Eur., BP, USP, JP, SAFC®

Supplier: MERCK PRODUCTION CHEMICALS

Titriplex® III (ethylenedinitrilotetraacetic acid disodium salt dihydrate), EMPROVE® EXPERT BP, Ph. Eur., ACS, JP, USP for biopharmaceutical production, SAFC®

Supplier: ProSci Inc.

Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. Complex formation between IL-21R and the common gamma chain (gammac) is required for signalling. IL-21R is expressed mainly on B cells (highest on mature, activated, follicular and germinal center B cells), NK cells and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells and keratinocytes. B cell IL-21R engagement induces Blimp1 (which mediates plasma cell differentiation) and is important for memory responses. IL-21R engagement on mouse NK cells enhances their cytotoxic activity and IFN-gamma production. IL-21R engagement on CD8+ T cells aids control of viral infection and tumour growth; IL-21R is also necessary for sufficient numbers of regulatory T cells to combat chronic inflammation. IL-21R expression is often upregulated in allergic skin inflammation, systemic lupus erythematosus and diffuse large B cell lymphoma (DLBCL).

Supplier: Cytiva

Ni Sepharose™ excel is an IMAC medium pre-charged with nickel ions very strongly bound to a chelating ligand. Samples that usually cause stripping of metal ions can, therefore, be loaded to the medium. Ni Sepharose™ excel is designed primarily for capture and purification of histidine-tagged proteins secreted into cell culture supernatants from eukaryotic cells such as insect cells or CHO cells.

Supplier: Ahlstrom-Munksjö

These qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers cover a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.