10968 Results for: "Sharps+Containers&pageNo=21"
Anti-TRIM21 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Bioss
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr-187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2.
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Analysing Sieve 500X500X80mm, 22.4mm Mw. With Beech Wood Framestainless Steel Wire Acc.To Din En 10 204 1 * 1 items
Supplier: NEXOPART
Analysing Sieve 500X500X80mm, 22.4mm Mw. With Beech Wood Framestainless Steel Wire Acc.To Din En 10 204 1 * 1 items
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OXYDE D'ETHYLENE 1,1MG/L DANS METHANOL 1 * 3 Ampoul
Supplier: CUSTOM MADE CHEMICALS LAB
OXYDE D'ETHYLENE 1,1MG/L DANS METHANOL 1 * 3 Ampoul
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Avantor in the heart of every lab!
Discover our special offers on laboratory products from Consumables to Equipment used in every lab!
Ultra-Low Temperature Freezers, TSX Universal
Supplier: Thermo Scientific
TSX Universal Series ULT Freezers are the pinnacle of reliability, sustainability, and innovation incorporating insights from over 80 years of experience to enhance every aspect of the system. Updates to the variable speed compressors has made the TSX Universal adaptable across all workflows. Available in four capacities, they are ENERGY STAR® certified with a 33% energy efficiency improvement, ACT labeled and produced in a Zero-Waste to Landfill certified facility.
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Anti-TRIM21 Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Stainless-Steel Test Sieve, 450mm Dia., in Pore Sizes 10mm and Smaller with ISO 3310/1 1 * 1 items
Supplier: Retsch GmbH
Stainless-Steel Test Sieve, 450mm Dia., in Pore Sizes 10mm and Smaller with ISO 3310/1 1 * 1 items
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Stainless-Steel Test Sieve 450mm Dia., in Pore Sizes Greater than 10mm with ISO 3310/1 1 * 1 items
Supplier: Retsch GmbH
Stainless-Steel Test Sieve 450mm Dia., in Pore Sizes Greater than 10mm with ISO 3310/1 1 * 1 items
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Filtered balance systems, XPert™
Supplier: LABCONCO
These portable systems provide user protection by keeping powders and particulates contained during weighing procedures. The built-in blower and HEPA filter are mounted in the upper plenum to save space, and the enclosures have low installation costs and require no outside ducting. Systems also provide quiet operation as low as 45 dBA, depending on face velocity.
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Stainless-Steel Test Sieve 450mm Dia., in Pore Sizes Greater than 10mm with ISO 3310/1 1 * 1 items
Supplier: Retsch GmbH
Stainless-Steel Test Sieve 450mm Dia., in Pore Sizes Greater than 10mm with ISO 3310/1 1 * 1 items
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STOPPPER PP NS 12.5 1 * 10 items
Supplier: Poulten & Graf
STOPPPER PP NS 12.5 1 * 10 items
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Laboratory chairs, standing rests, stools, Labster
Supplier: bimos
Apart from special hygiene features, a laboratory chair must always be ready for use at changing places of work. It should take up a minimum of space yet still offer maximum ergonomics and seating comfort so as to guarantee precise and concentrated work over longer periods of time. Labster is ideal for everyday use in the laboratory.
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Anti-TRIM21 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Supplier: Bioss
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr-187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2.
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Anti-TRIM21 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr-187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2.
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ROCKER 901 OIL-FREE ROTARY VANE PUMP 1 * 1 items
Supplier: witeg Labortechnik
ROCKER 901 OIL-FREE ROTARY VANE PUMP 1 * 1 items
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Thermal imager, testo 868s
Supplier: Testo
The testo 868s thermal imager, which makes work quicker and easier without foregoing professional thermal imaging technology. Generates error-free and objectively comparable infrared images using its handy functions. The IFOV warner, testo ɛ-Assist and testo ScaleAssist mean you can avoid measurement errors and not only effortlessly achieve optimum setting of emissivity (ɛ) and reflected temperature (RTC) for building thermography, but also of colour scale. This characterised by its professional measuring performance and its easy handling. It has the best thermal image quality in its class, an integrated digital camera and impressive smart functions. The case supplied with the thermal imager means it can be conveniently transported.
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Anti-TRIM21 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Supplier: Bioss
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr-187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2.
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Anti-TRIM21 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Supplier: Bioss
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr-187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2.
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Anti-TRIM21 Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Phalloidin conjugates
Supplier: Biotium
Phalloidin is a toxin isolated from the deadly Amanita phalloides mushroom. It is a bicyclic peptide that binds specifically to F-actin. Fluorescent conjugates of phalloidin are convenient tools to investigate the distribution of F-actin in fixed and permeabilised cells or tissue sections. One unit (U) of phallodin is sufficient to stain one sample (200 µl staining volume). A highly selective actin filament stain for fixed and permeabilised cells. Labeled phalloidins have similar affinity for both large and small filaments.
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Perfection and Performance Laboratory Refrigerators with Stainless Steel Inner Liner, SRPvh & SRPvg
Supplier: Liebherr
Glass/steel door high-volume refrigerators with forced air cooling. White steel exterior and stainless-steel interior. Choose between two temperature stability options to suit differing lab requirements. The intuitive user interfaces provide useful extended multi-functionality, e.g. a maintenance timer, and the LED interior lighting ensures good visibility of the contents of these large appliances. Advanced connectivity options to suit varying requirements for simplified data storage, temperature control and alarm signals. These advanced lab fridges also feature a +2 °C safety device to protect sensitive contents from freezing.
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Anti-TRIM21 Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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SONOREX DIGITEC DT 512 H, ULTRASONIC BATH, 230 V~ 50/60 HZ, ID 300X240X200 MM 13,0 L, S/S DIGITAL DISPLAY TIMER 1, 2, 3, 4, 5, 1 0, 15,30 MIN AND CONTINUOUS, ULTRASONIC PEAK OUTPUT 860 W, HF OUTPUT 215 WEFF., HEATER 20 - 80 °C (68-176°F) THERMO 1 * 1 items
Supplier: BANDELIN-ELECTRONIC
SONOREX DIGITEC DT 512 H, ULTRASONIC BATH, 230 V~ 50/60 HZ, ID 300X240X200 MM 13,0 L, S/S DIGITAL DISPLAY TIMER 1, 2, 3, 4, 5, 1 0, 15,30 MIN AND CONTINUOUS, ULTRASONIC PEAK OUTPUT 860 W, HF OUTPUT 215 WEFF., HEATER 20 - 80 °C (68-176°F) THERMO 1 * 1 items
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Refrigerators, Compact, Midi
Supplier: GRAM
The unique air distribution system combined with a finned tube evaporator results in excellent temperature consistency for biostorage: the evaporator design eliminates the risk of 'cold walls', which can damage delicate items stored touching the sides of the cabinet. Whilst the air distribution system which directs the cold air down the rear of the cabinet and back up to the evaporator fan at the top, ensures a uniform temperature throughout.
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Software for HPLC method development, ChromSwordAuto® 5 and ChromSwordAuto® 5 Hitachi Edition
Supplier: COLLECTION PREFIX HPLC
ChromSwordAuto® 5: Communicates directly with the HPLC instrument in order to create a fully automated HPLC or UHPLC method development station. The unique ChromSwordAuto® software is capable of developing and optimising HPLC methods fully automatically within just a few hours. Methods already in use can also be optimised, thus reducing analysis time considerably. All you have to do is place the sample in the autosampler, set a few parameters and start the optimisation process. ChromSwordAuto® then predicts the method conditions and controls the HPLC system connected in recording the chromatograms. These are analysed by the software and the optimal conditions determined. The rapid optimisation mode can be used to provide an overview of the performance of the column/solvent system selected or to rapidly screen columns and eluents considered for use. The fine optimisation mode additionally collects and evaluates further ancillary data and produces up to 10 sets of alternative optimal HPLC conditions. Both of these operating modes can be applied in combination with column and solving switching procedures in order to try a variety of column/solvent combinations or to establish optimal pH conditions – fully automatically.
Main features include:
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Dissolved oxygen meters, bench, Orion™ Versa Star Pro™
Supplier: Thermo Orion
These bench top meters with dissolved oxygen / RDO module meet most challenging applications for dissolved oxygen and temperature. The meters offer interchangeable measurement modules that allow multiple users to customise four separate channels to meet their specific requirements.
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Orion™ Versa Star™ Pro™ Multi-Parameter Meter, Bench
Supplier: Thermo Orion
This meter offers interchangeable measurement modules that allow multiple users to customise four separate channels to meet their specific requirements.
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Multi-parameter meters, handheld, HQ series
Supplier: Hach
Robust and intuitive portable meters, instilling confidence in reporting and managing your results.
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Heracell™ VIOS CO₂ incubators
Supplier: Thermo Scientific
The Heracell™ VIOS series has been designed for sensitive cultures like stem and primary cells in leading research, pharmaceutical and clinical applications. The units are available with either electropolished stainless steel or 100% pure copper interiors and have adjustable, perforated shelving, easy to clean corners with convenient access port and a reversible exterior door for added flexibility.
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Conductivity meters, bench, Orion™ Versa Star™ Pro™
Supplier: Thermo Orion
These bench top meters with conductivity module meet most challenging applications for conductivity, total dissolved solids (TDS), salinity, resistivity and temperature. The meters offer interchangeable measurement modules that allow multiple users to customise four separate channels to meet their specific requirements.