94231 Results for: "Sealing+Compounds&pageNo=9"

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PK 11195 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Benzodiazepine receptor ligand.

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H-9 HCl ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

An excellent affinity ligand for chromatographic purification of protein kinases. Inhibits protein kinases (Ki's: PKA=1.9 µM; PKC=18 µM; PKG=0.87 µM; MLCK=70 µM).

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Phloretin ≥98%

Supplier: ENZO LIFE SCIENCES

PKC inhibitor

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Erbstatin analog ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

EGFR inhibitor

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Calyculin A ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Inhibitor of PP1 and PP2A

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Triacsin C 1mg/ml ≥90% (by TLC)

Supplier: ENZO LIFE SCIENCES

Acyl-CoA synthetase inhibitor

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Gö 6976 ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

PKC inhibitor

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(±)-Blebbistatin ≥98%

Supplier: ENZO LIFE SCIENCES

Inhibitor of non-muscle myosin II

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Ikarugamycin ≥95% (by HPLC, TLC)

Supplier: ENZO LIFE SCIENCES

Ikarugamycin inhibits the uptake of oxidized low-density lipoprotein in mouse macrophages. It blocks PMA and Nef-mediated cell surface CD4 down-regulation. Ikarugamycin is emerging as a general inhibitor of clathrin-coated pit-mediated endocytosis and appears to be a useful agent for studying the process of endocytosis.

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1,9-Pyrazoloanthrone ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Potent, cell permeable, selective, and reversible inhibitor of c-Jun N-terminal kinase (JNK) (IC50=40nM for JNK-1 and JNK-2 and 90nM for JNK-3). The inhibition is competitive with respect to ATP. Exhibits over 300-fold greater selectivity for JNK as compared to ERK1 and p38. Inhibits the phosphorylation of c-Jun and blocks the expression of IL-2, IFN-γ, TNF-α, and COX-2. Blocks IL-1-induced accumulation of phospho-Jun, induction of c-Jun transcription and anti CD3-induced apoptosis of CD4+ CD8+ thymocytes.

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GW 9508 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

High potency synthetic agonist at GPR40.

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Eicosapentaenoyl ethanolamide ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Eicosapentaenoyl ethanolamide ≥98% (by TLC)

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α-Hydroxyfarnesylphosphonic acid (synthetic) ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=30 nM) and in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=35.8 µM and 67 µM respectively). α-Hydroxyfarnesylphosphonic acid inhibited (1 µM) Ras processing in Ha-ras-transformed NIH 3T3 fibroblasts.

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AAL-993 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Highly potent inhibitor of VEGFR-1 (IC50=130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM).

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Z-Asp-2,6-dichlorobenzoyloxymethylketone ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Caspase inhibitor

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1-Methyl-3,4-bis(3-indolyl)maleimide ≥98%

Supplier: ENZO LIFE SCIENCES

Negative control for the protein kinase C (PKC)-inhibitory activity.

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Bisindolylmaleimide III ≥98%

Supplier: ENZO LIFE SCIENCES

PKC inhibitor

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1400W dihydrochloride ≥98%

Supplier: ENZO LIFE SCIENCES

iNOS inhibitor

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Captopril ≥98%

Supplier: ENZO LIFE SCIENCES

Inhibitor of ACE and leukotriene hydrolase

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Y-27632 dihydrochloride ≥98% (by HPCE)

Supplier: ENZO LIFE SCIENCES

ROCK inhibitor

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Ubiquinone-10 ≥90% (by HPLC)

Supplier: ENZO LIFE SCIENCES

MPTP inhibitor

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Pioglitazone ≥97% (by HPLC)

Supplier: ENZO LIFE SCIENCES

PPARgamma activator.

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(S)-(+)-Camptothecin ≥98%

Supplier: ENZO LIFE SCIENCES

Potent antitumor agent

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CK-666 ≥95%

Supplier: ENZO LIFE SCIENCES

Cell permeable inhibitor human (IC50=4µM), fission yeast (IC50=5µM), S. cerevisiae (IC50=12µM) and bovine (IC50=17µM) Arp2/3 complex between Arp2 and Arp3. Inhibits Listeria motility (IC50=7µM).