Supplier: MEMMERT

The range includes forced convection models with a temperature range up to 300 °C. There is a choice of two different displays, SingleDISPLAY or TwinDISPLAY depending on the application.

Supplier: Binder

CO₂ incubators with a built in CO₂ sensor which can be sterilised. Units offer optimum growth conditions for cell cultures and meet demanding requirements for best possible cell growth and maximum sample safety. The ANTI.PLENUM design minimises surfaces due to the seamless, deep-drawn inner chamber without fixtures and featuring an integrated shelf support system. This reduces the risk of contamination, giving less surface area and fewer parts to clean manually, and removes the running costs of consumables. Reliable decontamination is provided by the standard-compliant 180 °C hot air sterilisation routine which completely eliminates contaminants and ensures the inner chamber is completely sterilised.

Supplier: MEMMERT

Humidity chambers which have corrosion resistant, stainless steel inner chamber and housing for long-term climatic tests at constant temperature and humidity. Ideal for food processing, cosmetics, pharmaceutical, biotechnology and electronics industries. Units feature an auto diagnostic system with fault indication for temperature and humidity control. The working chamber is heated on all six sides; this together with electronic humidity control prevents condensation forming in the chamber. Distilled water is supplied from an external 2,5 litre tank by means of a self priming pump. lnternal log memory 1024 kB (ring buffer) for all relevant data, capacity is approximately three months at one minute intervals. GLP/GMP compliance is assisted by the USB interface and 'Celsius' software for programming and documentation.

Supplier: Bioss

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterised by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene. SMN, also known as Gemin1, SMN1, SMNT and BCD541, exists as four isoforms produced by alternative splicing. SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies). Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, and nuclear SMN mediates recycling of pre-mRNA splicing factors. Nearly identical telomeric and centromeric forms of SMN encode the same protein; however, only mutations in the telomeric form are associated with the disease-state SMA. SMN is expressed in a wide variety of tissues including brain, kidney, liver, spinal cord and moderately in skeletal and cardiac muscle.

Supplier: THERMO H + P LABORTECHNIK

Compact magnetic stirrers with VARIOMAG drive, hermetically sealed in resistant stainless steel housing (except MINI units which are plastic), making these stirrers ideal for use directly in water baths. MINI stirrers are ideal for integration in analytical instruments, cuvette holders or photometers due to their size, however these plastic units are not designed for use directly in baths. There are units with up to 60 stirring positions in this range, and a choice of three external control units. The TELEMODUL 7 has one power setting, the TELEMODUL 20 C has four power settings: 25%; 50%; 75% and 100% and can store three programmes, the TELEMODUL 40 C features ten different power settings from 10 to 100% and a RS232 interface.

Supplier: Ahlstrom-Munksjö

These qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers cover a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.

Supplier: BIGNEAT

Upgrade base tray to Stainless Steel (316L) 1 * 1 items

Supplier: Portwest

The DX4 holster trouser is ergonomically designed and uses the targeted placement of dynamic 4X stretch fabrics to give maximum range of movement when working. The trouser features a high-rise back waistband with side elastication, ensuring protection in all working positions.

Supplier: HEATHROW

Compact digital orbital shaker which is packed full of high end design features making this laboratory shaker a versatile unit for a vast range of protocols.

Supplier: Whatman products (Cytiva)

LMd 050/0/03 PTFE ized Sieve 1 * 1 items

Supplier: Abnova

Mouse MAB raised against partial recombinant mouse Nlgn1. 1 * 100 µG

Supplier: Abnova

Mouse MAB raised against partial recombinant mouse Nlgn1. 1 * 100 µG

Supplier: Bioss

HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localises to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organisation and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms. In Drosophila, the WAVE/ARC pathway may affect the development of the nervous system. HSPC300 is thought to localise to axons of the central nervous system of Drosophila embryos and thus may also be involved in axonogenesis. In addition, HSPC300 is thought to be necessary for synaptic morphogenesis by motoneurons. In mice, the knockout of the WAVE complex leads to learning and memory defects, and it is therefore hypothesized that HSPC300 may also be involved in cognitive functions. Genetic depletion of HSPC300 results in cytoskeletal abnormalities and prevents cytokinesis of cells, suggesting that decreased levels of HSPC300 may be associated with tumor suppression.

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant rat Nlgn1. 1 * 100 µG

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant rat Nlgn1. 1 * 100 µG

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant mouse Nlgn1. 1 * 100 µG

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant mouse Nlgn1. 1 * 100 µG

Supplier: Avantor Fluid Handling

Versatile piston pump systems for high-accuracy fluid delivery and dispensing with an intuitive touch-screen interface.

Supplier: Bioss

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterised by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene. SMN, also known as Gemin1, SMN1, SMNT and BCD541, exists as four isoforms produced by alternative splicing. SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies). Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, and nuclear SMN mediates recycling of pre-mRNA splicing factors. Nearly identical telomeric and centromeric forms of SMN encode the same protein; however, only mutations in the telomeric form are associated with the disease-state SMA. SMN is expressed in a wide variety of tissues including brain, kidney, liver, spinal cord and moderately in skeletal and cardiac muscle.

Supplier: HORIBA

ACTIVATED CARBON FOR RECLAIMER SR-310 1 * 500 g

Supplier: Merck

Fast method development of complex samples across the pH range from 1,5 to 10,5 with different mobile phases and temperature conditions.
Purospher® STAR RP-18 endcapped HPLC columns are designed for universal use. Basic, neutral and metal-chelating compounds can easily be separated with simple mobile phases – naturally without peak tailing. Thanks to its outstanding performance and stability, Purospher® STAR RP-18 endcapped offers maximum flexibility in method development. Robust methods can be developed over the entire pH range from 1,5 to 10,5. High pH-stability allows the separation of strongly basic compounds with alkaline eluents. The combination of high purity silica, best all-round retention characteristics, outstanding pH stability up to pH 10,5, and suitability for up to 100% aqueous mobile phases, make Purospher® STAR RP-18 endcapped an all-round top performance column, almost universal in its range of applications.

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant rat Nlgn1. 1 * 100 µG

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant rat Nlgn1. 1 * 100 µG

Supplier: Agencinox

SCOOP W/HANDLE 2L 233xØ115mm INOX 316 1 * 1 items

Supplier: KING DISPOSABLES

RAMASSETTE EN PLASTIQUE BAC FERME 31CM 1 * 1 items

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant rat Nlgn1. 1 * 100 µG

Supplier: PONT PACKAGING

BOTTLE 1000ML WHITE W/O SCREWCAP 31,5MM 1 * 12 items

Supplier: Abnova

Mouse monoclonal antibody raised against partial recombinant rat Nlgn1. 1 * 100 µG

Supplier: VWR Chemicals

VWR® dehydrated culture media that has been granulated offers both convenience and safety benefits. The correct dissolution of culture media is critical to achieving the best performance. Granulated culture media saves time in the preparation of ready to use culture media. In addition, granulation reduces dust generation, so handling the product is more pleasant and safer for the user, making it a much cleaner and safer working environment.

Supplier: Basan

Stainless Steel Handle, Ø31 mm, 1510 mm, Blue 1 * 1 items