17678 Results for: "Polyimide&pageNo=30&view=easy"

Supplier: SCHUELKE MAYR

well-sett transparent, 30L 1 * 1 items

Supplier: SCHUELKE MAYR

well-sett, faucet/lid, transparent 1 * 1 items

Supplier: ProSci Inc.

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.

Supplier: ProSci Inc.

The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterised by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells. IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibroblastic tumor (IMT). In pulmonary nodular lymphoid hyperplasia (PNLH), there are an increased number of IgG4+ plasma cells.

Supplier: ProSci Inc.

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.

Supplier: ProSci Inc.

FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin as a pioneer factor. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

FOXA1 in breast cancer is highly correlated with ERalpha+, GATA3+, and PR+ protein expression as well as endocrine signaling. FOXA1 acts as a pioneer factor for ERa in ERalpha+ breast cancer, and its expression might identify ERalpha+ cancers that undergo rapid reprogramming of ERa signaling that is associated with poor outcomes and treatment resistance. Conversely, in ERalpha− breast cancer FOXA1 is highly correlated with low-grade morphology and improved disease free survival. FOXA1 is a downstream target of GATA3 in the mammary gland. Expression in ERalpha− cancers may identify a subset of tumors that is responsive to other endocrine therapies such as androgen receptor antagonist treatment. [Wiki].

Supplier: Dräger

The powered air-purifying respirator (PAPR) X-plore 8000 offers a number of user friendly standard and specialised carrying systems for standard and decontamination applications. Dräger has also developed a wide range of tight- and loose-fitting headgear such as half and full-face masks, short and long hoods and helmets with visor and protective visor. Standard and enhanced flexibility hoses are available and compatibility is ensured. Modular components: A wide range of components for every application.

Supplier: MACHEREY-NAGEL

The high purity CHROMABOND® adsorbents can be used for a self-filling of SPE columns or further analytical applications.

Supplier: Thermo Fisher Scientific

Rigid PC frame, thin-walled PP wells. Ultra-rigid 96-well PCR plates with rounded V-bottom wells designed for robotic applications.

Supplier: SARSTEDT

TUBE, REAGENT AND CENTRIFUGE, 25ML, 90X25MM, NON-STERILE, CONICAL, SKIRTED, TRANSPARENT, SCREW CAP ASSEMBLED, POLYPROPYLENE 1 * 500 items

Supplier: Roth Carl

Metal tube connectors 1 * 1 items

Supplier: LAMAPLAST

COVER FOR BOX 40X30CM 1 * 1 items

Supplier: SCHUELKE MAYR

well, 30L, without faucet 1 * 1 items

Supplier: HIRSCHMANN

Rea-Son® Less Foam Can 30L 1 * 1 items

Supplier: TRESTON

Upright tube, 500, light grey 1 * 1 items

Supplier: Ahlstrom-Munksjö

Extraction Thimbles, ET/C, 30x80 mm, Cellulose 1 * 25 items

Supplier: TRESTON

Upright tube, 790, light grey 1 * 1 items

Supplier: ProSci Inc.

Villin (VIL1) is an epithelial cell-specific Ca2+-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis. Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium. Appears to regulate cell death by maintaining mitochondrial integrity. Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. Upon S.flexneri cell infection, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination. [UniProt].

Supplier: DELTALAB

SILICONE TUBE 8X14MM 1 * 15 m

Supplier: GERHARDT

ADDITIONAL PLATE FOR VAPODEST 300 1 * 1 items

Supplier: NEUBERT VOLUME GLASSWAERE

INSTALL FILTER / SPLASHGUARD 1 * 1 items

Supplier: TENAK

30mm high dividers for 50mm high cryobox, 16x16 = 256 cells, cardboard, for 133x133mm cryobox 1 * 1 items

Supplier: Thermo Orion

This electrode with built-in temperature sensor is ideal for any application where the use of metallic reference electrodes would contaminate the samples. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.

Supplier: BTX

The High Throughput ECM™ 830 system offers a multi-well electroporation technology for processing multiple samples in seconds. Using the HT multi-well plates instead of traditional cuvettes, the researcher can transition from a single cuvette to either a 25-well or 96-well electroporation plate by using one simple plate handler. This increases yields and the number of experiments run in a single day. Experiments take seconds to run, allowing for quick and efficient optimisation of the electrical and biological parameters. Once optimised, samples are rapidly processed increasing yields and saving valuable time and money.

Supplier: Corning

Corning® Synthegel™ 3D matrices are chemically defined peptides that self assemble into nanofibers which crosslink to form tuneable hydrogels. These hydrogels provide a robust and reproducible microenvironment for 3D culture of physiological spheroids and hiPS cells. The Synthegel™ matrix kits provide negligible variability and a more controlled substrate for in vivo-like 3D cell culture. Such a platform is needed for cancer research, stem cell research, and drug screening in a 3D format.

Supplier: Hach

TUBING TYGON .375 OD 1 * 1 items

Supplier: DELTALAB

RACK 200X70X60MM CAPACITY (6X2) 28MM 1 * 1 items

Supplier: NEUBERT VOLUME GLASSWAERE

CENTR TUBE 30ML 28X100MM GL32 W/O SC/CAP 1 * 1 items

Supplier: NEUBERT VOLUME GLASSWAERE

BUILT - IN / SPLASH PROTECTION NS29/32 1 * 1 items

Supplier: HAMILTON BONADUZ

NEEDLE N730 L=51MM PS1 1 * 6 items