Supplier: Shenandoah Biotechnology

Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine that is constitutively produced by thymus tissue and activated peripheral blood mononuclear cells (PBMCs), including dendritic cells. TARC signals through the CCR4 receptor to induce chemotaxis of Type 2 T helper (Th2) cells. TARC is important in asthma and allergic diseases, along with bacterial and viral infections.

Supplier: Shenandoah Biotechnology

Stromal cell-derived factor-1 alpha (SDF-1 α), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1α signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1 α share 99% sequence identity.

Supplier: Bel-Art Products, a Part of SP

Secador® model 2.0, 3.0 and 4.0 auto desiccator cabinets are made from polycarbonate, which features a UV light blocker and is resistant to staining, crazing, and chemical attack.

Supplier: Corning

This cabinet-style LSE™ shaking incubator is constructed with mirrored stainless steel interior and cold rolled steel exterior. Built in orbital shaker accepts a large assortment of platforms and clamps that can accommodate flasks, petri dishes and test tube racks. Mechanical convection provides a safe, stable temperature environment and fast chamber temperature recovery after opening the door.

Supplier: Lovibond

Comparator 2000+ is a versatile modular system for testing water.

Supplier: Shenandoah Biotechnology

Galectin-1 belongs to the lectin family of carbohydrate binding proteins and binds glycans as both a monomer and a homodimer. Galectin-1 is produced in peripheral lymphoid organs and inflammatory sites. Galectin-1 plays important roles in acute and chronic inflammatory processes, cell growth, cell proliferation, and induces apoptosis of activated T cells. Galectin-1 also modulates cytokine secretion and inhibits pro-inflammatory cytokine production.

Supplier: Shenandoah Biotechnology

Exodus-2, also known as CCL21 and 6Ckine, is a chemokine that is strongly produced in the human lymph nodes and spleen. Exodus-2 signals through the chemokine receptor CCR7 to regulate thymocyte and activated T cell migration. Exodus-2 also mediates the homing of lymphocytes to the lymphatic system. Human and mouse Exodus-2 proteins share greater than 85% amino acid sequence identity.

Supplier: Shenandoah Biotechnology

Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.

Supplier: GLW

Cryoboxes, PP, natural or coloured, without divider.

Supplier: VISION ENGINEERING

Mantis Iota compact ergonomic stereo microscope. Easy to use with interchangeable lenses. Flexible articulated arm. Magnification from 3 to 8× (objectives to be added).

Supplier: Shenandoah Biotechnology

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains.

Supplier: VWR Collection

These VWR® pipette tips are made of clear, pre-tested PP resin and fit Rainin® LTS® pipettes.

Supplier: GLW

Cryoboxes made of PP, natural or coloured.

Supplier: Shenandoah Biotechnology

Macrophage inflammatory protein-3 alpha (MIP-3 α), also called CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. MIP-3 α expression is strongly induced by inflammatory signals, and downregulated by the anti-inflammatory cytokine interleukin 10 (IL-10). MIP-3 α signals through the G protein-coupled receptor CCR6 to function as a chemoattractant to lymphocytes and dendritic cells.

Supplier: Hettich

High performance, compact centrifuges developed for high sample throughput as well as for high sample volumes.

Supplier: Thermo Fisher Scientific

GelCode blue stain reagent is a ready-to-use protein stain based on colloidal coomassie dye G-250 that provides nanogram-level detection in polyacrylamide gels and for in-blot detection.

Supplier: Shenandoah Biotechnology

Interleukin 16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin 2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).

Supplier: UVEX

This autoclavable eye protection offers best wearers comfort, highest functionality and an innovative design. Suitable for use over prescription spectacles.

Supplier: Shenandoah Biotechnology

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory lymphokine that functions during cell-mediated immmunity. MIF promotes fibroblast migration by inducing interleukin 1 (IL-1), interleukin 8 (IL-8), and matrix metalloproteinase (MMP) expression. In interferon-gamma-activated macrophages, MIF stimulates nitric oxide (NO) production and tumor necrosis factor-alpha (TNF-α) secretion.

Supplier: Shenandoah Biotechnology

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. While human SCF shows no activity on murine cells, murine and rat SCF are active on human cells.

Supplier: Shenandoah Biotechnology

Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.

Supplier: Shenandoah Biotechnology

Macrophage inflammatory protein-1 alpha (MIP-1 α), also known as CCL3, is a cytokine produced by macrophages. MIP-1 α binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1 α and MIP-1 β heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).

Supplier: Lovibond

CHECKIT® Comparator is a compact and handy colorimetric unit which is suitable for both mobile and static analysis work. Supplied with a generous number of different colour scales, it provides the basis for a comprehensive, easy-to use colorimetric analysis system.

Supplier: Shenandoah Biotechnology

Neuregulin 1-beta (NRG1-β) is one of many alternatively-spliced isoforms of the NRG1 gene and contains a soluble EGF-like domain. The EGF-like domain of NRG1-β signals through the ErbB2, ErbB3, and ErbB4 receptor tyrosine kinases. NRG1-β is an important growth factor involved in neuroinflammation, nerve regeneration, and cardiovascular processes.

Supplier: Cole Parmer

Advanced split beam optics ensure excellent accuracy and reproducibility.

Supplier: VWR Collection

Simple one-key reset operation resets MIN/MAX memories.

Supplier: Avantor Fluid Handling

Achieve high pressure, accuracy, and repeatability -- with an intuitive touch-screen interface.

Supplier: Brady

A rugged design offering seamless experience. Digitise data capture and automate your workflows with ease and accuracy with the V4500 Barcode Scanner.

Supplier: SI Analytics

TitroLine® 7500 KF is a volumetric generalist for a wide range of uses. Applications include KF volumetry, dead-stop titrations (SO₂, bromine number), dosing tasks and preparation of solutions. Ideal for KF analysis in pharmaceutical, chemical, food and mineral oil industries.

Supplier: Shenandoah Biotechnology

Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.