54467 Results for: "Nonidet®+P+40+Substitute+(NP-40)&pageNo=20"

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.

Supplier: LABCONCO

These portable systems provide user protection by keeping powders and particulates contained during weighing procedures. The built-in blower and HEPA filter are mounted in the upper plenum to save space, and the enclosures have low installation costs and require no outside ducting. Systems also provide quiet operation as low as 45 dBA, depending on face velocity.

Supplier: Bioss

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).

Supplier: Bioss

Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1 and histone H3 at 'Ser-10', which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA), phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP. Upon insulin-derived signal, acts indirectly on the transcription regulation of several genes by phosphorylating GSK3B at 'Ser-9' and inhibiting its activity. Phosphorylates RPS6 in response to serum or EGF via an mTOR-independent mechanism and promotes translation initiation by facilitating assembly of the preinitiation complex. In response to insulin, phosphorylates EIF4B, enhancing EIF4B affinity for the EIF3 complex and stimulating cap-dependent translation. Is involved in the mTOR nutrient-sensing pathway by directly phosphorylating TSC2 at 'Ser-1798', which potently inhibits TSC2 ability to suppress mTOR signaling, and mediates phosphorylation of RPTOR, which regulates mTORC1 activity and may promote rapamycin-sensitive signaling independently of the PI3K/AKT pathway. Mediates cell survival by phosphorylating the pro-apoptotic proteins BAD and DAPK1 and suppressing their pro-apoptotic function. Promotes the survival of hepatic stellate cells by phosphorylating CEBPB in response to the hepatotoxin carbon tetrachloride (CCl4).

Supplier: MICRONOVA

BUCKET RECTANGLE SS 8 GALLON W/HANDLE 1 * 1 items

Supplier: Amarell

Range finder, set, DIN12793, measuring range:0.60-2.00:0.005g/cm , without thermometer, 4 instruments in stuffed case, reference tem perature:20C. 1 * 1 items

Supplier: witeg Labortechnik

Tubing threaded 32x150x2.0mm svl30 with screw threaded straight,acc. to din 12216, with iso screw thread,made of borosilicate glass, available with screw thread gl, rd or svl 1 * 1 items

Supplier: SAMCO

PIPETTE T/FER EXT/F/TIP STER PE 35.4ML 1 * 4.000 items

Supplier: Amarell

Areometer, DIN12791, L50 series, measuring range: 1.60-1.65:0.0005g/cm , without thermometer, reference temperature:20C, length:335 mm, suitable for government verification. 1 * 1 items

Supplier: CANNON INSTRUMENT

Viscosity Standard N350,,500 ml,,820 mPa s at 20C 1 * 500 mL

Supplier: Amarell

Areometer, DIN12791, M50 series, measuring range: 0.90-0.95:0.0010g/cm , without thermometer, reference temperature:20C, length:270 mm, suitable for government verification, with works certificate. 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, M50 series, measuring range: 1.25-1.30:0.0010g/cm , without thermometer, reference temperature:20C, length:270 mm, suitable for government verification. 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, L50 series, measuring range: 1.50-1.55:0.0005g/cm , without thermometer, reference temperature:20C, length:335 mm, suitable for government verification. 1 * 1 items

Supplier: Amarell

Areometer, DIN 12791, M50, 1,00-1,05:0,0010g/cm , ref. temp, 20C, without thermometer max. 270mm long, suitable for government ver ification 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, M50 series, measuring range: 0.90-0.95:0.0010g/cm , without thermometer, reference temperature:20C, length:270 mm, suitable for government verification. 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, L50 series, measuring range: 1.65-1.70:0.0005g/cm , without thermometer, reference temperature:20C, length:335 mm, suitable for government verification. 1 * 1 items

Supplier: Amarell

Areometer, DIN 12791, M50, 0,65-0,70:0,0010g/cm , ref. temp. 20C, without thermometer max. 270mm long, suitable for government ver ification 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, L50 series, measuring range: 1.55-1.60:0.0005g/cm , without thermometer, reference temperature:20C, length:335 mm, suitable for government verification. 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, L50 series, measuring range: 1.10-1.15:0.0005g/cm , without thermometer, reference temperature:20C, length:335 mm, suitable for government verification. 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, L50 series, measuring range: 1.30-1.35:0.0005g/cm , without thermometer, reference temperature:20C, length:335 mm, suitable for government verification. 1 * 1 items

Supplier: Amarell

Areometer, DIN12791, L50 series, measuring range: 1.45-1.50:0.0005g/cm , without thermometer, reference temperature:20C, length:335 mm, suitable for government verification. 1 * 1 items

Supplier: Epredia

Microslide 90 frosted 20mm glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Kautex

SCREW CAP PE RED WITH PULL-OFF 60MM 1 * 1.000 items

Supplier: Amarell

Areometer, DIN12791, M50 series, measuring range: 0.95-1.00:0.0010g/cm , without thermometer, reference temperature:20C, length:270 mm, suitable for government verification, with works certificate. 1 * 1 items

Supplier: Amarell

Saccharimeter Brix, 0-30:1/1Brix, with correction scale, with therm. 0+40/50:1C, red or blue special liquid, ref. temp. 20C, 300m m long 1 * 1 items

Supplier: Amarell

Areometer for plants, DIN 12792 (old), 1,610-1,842:0,002g/cm , ref. temp. 20C, without thermometer 325mm long, suitable for govern ment verification 1 * 1 items

Supplier: GERING

HYDROMETERIMET 9-12 PLATO CALIB.20C 1 * 1 items

Supplier: ZEISS

Dust protection glass for Stemi 2000/DV4/DR 1 * 1 items

Supplier: Bioss

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).

Supplier: Bioss

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).