94175 Results for: "N-Boc-S-trityl-L-cysteine&pageNo=9"
Rockout ≥98% (by HPLC)
Supplier: Enzo Life Sciences
A cell permeable, selective, and ATP-competitive inhibitor of Rho kinase (ROCK) activity (IC50=25µM). Does not inhibit the activation of Rho nor does it affect the in vitro activities of MLCK, PKCα, and SAPK2a/p38α. Shown to be less potent than Y-27632.
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1-Azakenpaullone ≥95% (by NMR)
Supplier: Enzo Life Sciences
GSK-3beta inhibitor
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SU 9516 ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Cell permeable, potent, selective and ATP-competitive inhibitor of CDK2/cyclin A (IC50=22nM), CDK1/cyclin B (IC50=40nM) and CDK4/cyclin D1 (IC50=200nM). Has no effect on the activity of PKC, p38, PDGFRβ and EGFR (IC50>10µM). Displays anti-proliferative and pro-apoptotic properties in tumor cells. Inhibits proliferation of growth factor-stimulated colon carcinoma cells by binding to CDK2 and thus preventing the phosphorylation of pRb and its dissociation from E2F.
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CDK1/2 Inhibitor III ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Cell permeable triazolo-diamine compound that displays anti-proliferative properties in various human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).
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4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoline ≥97% (by 1H-NMR)
Supplier: Enzo Life Sciences
Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=51nM). Displays ~15-fold greater selectivity over p38α MAPK (IC50=740nM). Inhibits TGF-β-dependent cellular growth (IC50=89nM in NIH 3T3 mouse fibroblasts) and transcription activation (IC50=47nM in mink lung cells). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay.
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N-ω-Hydroxy-L-norarginine acetate salt ≥97% (by TLC)
Supplier: Enzo Life Sciences
Potent and reversible arginase inhibitor. Specifically interacts with the manganese-cluster of the arginase active site. Does not act as a substrate or as an inhibitor of NOS.
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BIX 01294 trihydrochloride, hydrate ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Selective and cell permeable inhibitor of G9a histone methyltransferase.
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TGX-221 ≥98% (by NMR)
Supplier: Enzo Life Sciences
PI3 kinase p110beta inhibitor
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PI103 ≥97% (by HPLC)
Supplier: Enzo Life Sciences
Potent, cell permeable and ATP-competitive inhibitor of DNA-PK, phosphoinositide 3-kinase (PI(3)K), the rapamycin-sensitive (mTORC1) and rapamycin-insensitive (mTORC2) complexes of the protein kinase mTOR. Exhibits little activity towards a panel of more than 40 other kinases even at concentrations as high as 10µM. Effectively blocks cell proliferation in glioma cell lines both in vitro and in vivo.
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UPF1035 ≥95% (by HPLC)
Supplier: Enzo Life Sciences
PARP-2 specific inhibitor with 60-fold selectivity for PARP-2 (IC50=0.15 ± 0.04μM) over PARP-1 (IC50=9.0 ± 0.7μM). Can be used for further characterization of PARP-2 in pathophysiological conditions.
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DL-sulphoraphane (synthetic) ≥98% (by UPLC)
Supplier: Enzo Life Sciences
R,S-Sulforaphane is a synthetic version of the naturally occurring compound, R-sulforaphane, from Broccoli. It is a racemic mixture of both the R and S isomers.
Potent, selective inducer of phase II detoxification enzymes. Inhibits chemically induced mammary tumor formation in rats. Inhibits LPS-induced HMGB1 (high mobility group box 1) secretion.
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Resibufogenin (from Bufonis venom) ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Specific Na⁺/K⁺-ATPase inhibitor.
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Cinnamtannin B-1 ≥90% (by 1H-NMR)
Supplier: Enzo Life Sciences
Potent antioxidant
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Oligomycin (from Streptomyces diastatochromogenes) ≥90%
Supplier: Enzo Life Sciences
F-ATPase inhibitor.
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Venturicidin A ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Inhibitor of mitochondrial ATP synthase
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Antimycin A (from Streptomyces species) ≥90% (by HPLC)
Supplier: Enzo Life Sciences
Antibiotic
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Oligomycin B (from Streptomyces sp. MST-AS5339) ≥95% (by HPLC)
Supplier: Enzo Life Sciences
F-ATPase inhibitor.
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(+)-Catechin monohydrate ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Free radical scavenger.
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Ciprofloxacin hydrochloride monohydrate ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Fluoroquinolone antibacterial agent. Inhibits bacterial DNA gyrase (topoisomerase). Inhibits cell division and causes double-strand breaks in the bacterial chromosome. Broad-spectrum antibiotic effective against Gram-positive, Gram-negative and anaerobic bacteria.
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(+)-Indolactam V ≥95% (by 1H-NMR)
Supplier: Enzo Life Sciences
(+)-Indolactam V ≥95% (by 1H-NMR)
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Cyclophosphamide monohydrate (synthetic) ≥97% (by HPLC)
Supplier: Enzo Life Sciences
Alkylates DNA, forming DNA-DNA cross-links that result in inhibition of DNA synthesis and cell death.
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Mitoxantrone dihydrochloride (synthetic) ≥97%
Supplier: Enzo Life Sciences
Antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative. Induces DNA damage by intercalating into DNA and inhibiting topoisomerase II. Induces interstrand DNA cross-links and DNA-protein cross-links in cellular systems. Has been shown to be an inhibitor of DNA methylation.
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DETA NONOate (NOC-18) ≥97% (by 1H-NMR)
Supplier: Enzo Life Sciences
Nitric oxide (NO) donor.
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Supplier: GRANT INSTRUMENTS
Supplier: BOCHEM
Supplier: VWR Collection
Supplier: OMEGA BIO-TEK
Supplier: DWK Life Sciences
Supplier: Thermo Fisher Scientific
Supplier: VWR Collection
Supplier: Oxford Nanopore Technologies
Supplier: Industrial Physics
Supplier: AAT BIOQUEST
Supplier: Integra
Supplier: Palbam
Supplier: VWR Collection
Supplier: Integra
Supplier: VWR Collection
Supplier: FACELLITATE
Supplier: NANOENTEK
Supplier: Greiner Bio-One