7097 Results for: "N,N-Dimethyl+2-boronobenzenesulphonamide"

Supplier: Enzo Life Sciences

Cell permeable modulator of Ins(1,4,5)-P3-induced Ca²⁺ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca²⁺ entry (75µM).

Supplier: Restek

Rxi®-5Sil MS stationary phase incorporates phenyl groups in the polymer backbone. This improves thermal stability, reduces bleed, and makes the phase less prone to oxidation. These columns are ideal for GC-MS applications requiring high sensitivity, including use in ion trap systems.

Supplier: VARIAN

Bond Elut™ C2 is a fairly non-polar sorbent because of the short chain length of the functional group. C2 is often used during the process of method development if analytes are retained too strongly on a C8 or C18 phase. The polarity of C2 is slightly lower than a cyano phase for polar interactions.

Supplier: Enzo Life Sciences

A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50=6 nM). It efficiently blocks IGF-1R activity, reduces pAKT and pERK1/2, induces apoptosis in IGF-1R-positive tumor cells and causes complete tumor regression in xenografted and allografted mice. Picropodophyllin downregulates IGF-1R by interfering with the action of β-arrestin 1/MDM2. It causes tumor regression and attenuates invasiveness of uveal melanoma cells. It displays beneficial effects on tumor growth, angiogenesis, bone disease and survival in a mouse multiple myeloma model. It attenuates intimal hyperplasia after vascular injury. Inhibition of IGF-1R is non-competitive with ATP.

Supplier: MP Biomedicals

Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells.

Supplier: PerkinElmer

General purpose columns with a highly versatile phase that is extremely rugged, exhibiting long column lifetime and high operating temperatures. Ideal for the analysis of non polar petrochemical samples, such as detailed hydrocarbon analysis, hydrocarbon gases, petroleum oxygenates, petroleum aromatics, fuels waxes, oils, sulphur compounds, mercaptains and carbon disulphide. It also an excellent phase for solvents, chemicals, flavours, fragrances, essential oils, air toxins, chlorofluorocarbons, pesticides and hydrocarbons.

Supplier: Merck

All Spectroquant® test kits can be used with the Prove range of spectrophotometers and Nova 60/60A instruments. Tests can be used not only on photometers and spectrophotometer from Merck, but also on photometers and spectrophotometers from other suppliers (programming details available on request). Spectroquant® cell test kits.

Supplier: GA

Xylene and chemical-resistant labels for the identification of microscope slides that will undergo long-term chemical exposure and immersion.

Supplier: Enzo Life Sciences

AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.

Supplier: USP

USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Supplier: MACHEREY-NAGEL

The high purity CHROMABOND® adsorbents can be used for a self-filling of SPE columns or further analytical applications.

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to pan symmetric di-methyl Arginine. 1 * 100 µl

Supplier: ANTIBODIES.COM

Rabbit monoclonal [ARC51197] antibody to pan symmetric di-methyl Arginine. 1 * 100 µl

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to Histone H3.1 (asymmetric di methyl Arg2). 1 * 100 µl

Supplier: GASTEC

GASTUBE TERT-BUTYL MERCAPTAN 1-15MG/M 1 * 10 items

Supplier: LGC Standards PROMOCHEM

METFORMIN HYDROCHLORIDE IMP. C (EP): N,N 1 * 100 mg

Supplier: CUSTOM MADE CHEMICALS LAB

25 COMPOSES 2G/L CHAQUE Acetone [CAS:67-64-1] tert.-Butanol [CAS:75-65-0] 2-Methylpentane [CAS:107-83-5] 3-Methylpentane [CAS:96-14-0] n-Hexane [CAS:110-54-3] Ethyl-tert-butylether (ETBE) [CAS:637-92-3] Methylcyclopentane [CAS:96-37-7] [C 1 * 20 Ampoul