4833 Results for: "Methyl+cyclopentanecarboxylate&pageNo=72&view=list"

Supplier: Thermo Orion

Use the Orion Star T940 all-in-one titrator for flexible pH, redox and ion concentration titrations including equivalence point titrations, preset pH or mV endpoint titrations plus multiple known addition (MKA) mode for automated known addition of various ions.

Supplier: Bioss

Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The C16orf72 gene product has been provisionally designated C16orf72 pending further characterization.

Supplier: Bioss

Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The C16orf72 gene product has been provisionally designated C16orf72 pending further characterization.

Supplier: Bioss

Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The C16orf72 gene product has been provisionally designated C16orf72 pending further characterization.

Supplier: MEMMERT

Humidity chambers which have corrosion resistant, stainless steel inner chamber and housing for long-term climatic tests at constant temperature and humidity. Ideal for food processing, cosmetics, pharmaceutical, biotechnology and electronics industries. Units feature an auto diagnostic system with fault indication for temperature and humidity control. The working chamber is heated on all six sides; this together with electronic humidity control prevents condensation forming in the chamber. Distilled water is supplied from an external 2,5 litre tank by means of a self priming pump. lnternal log memory 1024 kB (ring buffer) for all relevant data, capacity is approximately three months at one minute intervals. GLP/GMP compliance is assisted by the USB interface and 'Celsius' software for programming and documentation.

Supplier: UVP ULTRA VIOLET PRODUCTS

Cabinet c-10e cabinet only - add 4w el lamp 1 * 1 items

Supplier: Brand

These tips are manufactured under cleanroom conditions and are automatically packaged to ensure that the tips are consistently free from contamination.

Supplier: VWR Collection

VWR® incubating/refrigerating 5000I/5000IR orbital shakers are designed for a variety of shaking and incubating applications, such as cell culture, solubility studies, bacterial suspensions and extraction procedures. Large capacity platform holds up to 22,7 kg. Variable speed, microprocessor control provides consistent, uniform mixing action. Microprocessor will display last set point and will restart if power is interrupted. Ramping feature slowly increases speed to set point for added safety. The Accu-drive shaking system delivers exceptional speed control, accuracy, safety and durability. System continuously monitors shaking speed and will maintain set point even under changing loads. Displayed speed is accurate to 1% of set speed (when speed is above 100 min⁻¹), below 100 rpm, ±1 rpm.

Supplier: RPB SAFETY

The RPB T-Link respirator is a lightweight, multi-purpose TH3 respirator designed specifically for a range of industries, including healthcare, pharmaceutical, and industrial painting and coating. The advanced cradle provides unmatched comfort for the wearer, and keeps the lens and hood mounted solidly.

Supplier: ZEISS

Digital microscope 'Axiovert 5 digital' with integrated color camera; suitable for transmitted light brightfield, phase contrast Ph1 and reflected light fluorescence "RGB-UV". Eyepieceless technology, for use with tablets and computers.

Supplier: Rubbermaid Commercial Products

The ProSave® Ingredient and food storage mobile bin is a bulk food storage container on wheels. With a slanted front, sliding opening, and 32 ounce scoop, these food storage containers make it easy to transport ingredients.

Supplier: VWR Collection

Designed to hold multiple test tubes, test tube racks, vials or cylinders. Vortexing action is created by securing the top of the vessel in place while allowing the bottom to move freely in a defined orbit. Two stainless steel posts hold the support plate securely in place for quiet, rattle-free mixing. The support plate is easily adjustable by loosening knobs and moving the support plate up and down. The circular groove around the top of the taller post allows the support plate to be swung away from the tray for easy removal of samples. The suction cup feet dampen motion and prevent the unit from moving along the work bench. Made from stainless steel with corrosion resistant paint. Equipped with a powerful, permanent magnet motor with sealed ball bearings. Motor is rated for continuous duty.

Supplier: FRISTADS KANSAS

Trousers made of 65% polyester and 35% brushed cotton. The fabric has mechanical stretch, which ensures improved comfort, especially for jobs that require a lot of movement. Short and long sizes are available as well. Please contact Avantor for further details.

Supplier: RPB SAFETY

The RPB T-Link respirator is a lightweight, multi-purpose TH3 respirator designed specifically for a range of industries, including healthcare, pharmaceutical, and industrial painting and coating. The advanced cradle provides unmatched comfort for the wearer, and keeps the lens and hood mounted solidly.

Supplier: HAMILTON BONADUZ

The 700 series syringe is the original hand-fitted Hamilton syringe. This series of syringes is ideal for dispensing volumes from 0,5 to 500 µl. The stainless steel plunger is manufactured to fit the glass barrel with a tolerance smaller than 100 millionths of an inch, resulting in unsurpassed syringe life. Each syringe is manufactured to achieve the highest level of accuracy and precision possible.

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, providing choice between applications and configurations that best suit the users' needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions. The Cubis® II range of high-capacity micro balances with a maximum load between 32 and 111 g and a readability between 0,001 mg and 0,002 mg provide the ideal choice for a broad range of applications.

Supplier: ProSci Inc.

Hsp90 is a member of the heat shock protein 90 family that functions as a molecular chaperone and has ATPase activity. Hsp90 family proteins are highly conserved between isoforms and species. Several signal transduction pathways depend on Hsp90 function including erbB2, steroid hormone receptors (such as androgen, progesterone, glucocorticoid, and aryl-hydrocarbon), and hypoxia sensing (Hif1alpha). Recent reports show that tumor cells are more sensitive to Hsp90 inhibition and that Hsp90 from tumor cells is more sensitive to small molecule inhibitors (eg 17AAG). The mechanism of this differential sensitivity of normal versus tumor Hsp90 is not known (although mutation has been ruled out). One possible mechanism may be differences in post-translational modification of tumor Hsp90. Hsp90 is a cytoplasmic protein that forms a homodimer in vivo, and interacts with TOM34, AHSA1, HDAC6 and SMYD3.

Supplier: Thermo Fisher Scientific

AminoLink™ Plus Coupling Resin uses aldehyde-activated agarose beads for high-yield covalent coupling of antibodies (proteins) via primary amines to prepare columns for affinity purification.

Supplier: LABCONCO

Clean benches provide product protection from environmental contaminants for applications requiring a particulate-free work area, including plant tissue culture, electronic part inspection, syringe filling, medical device assembly, media plate preparation, and PCR.

Supplier: 3M

The 3M Speedglas Heavy-Duty Welding Helmet G5-01 builds on the 9100 series. Having more adjustable features than ever - from the colour as seen through the welding filter to the direction of the airflow and the level of coverage.

Supplier: LABCONCO

These portable systems provide user protection by keeping powders and particulates contained during weighing procedures. The built-in blower and HEPA filter are mounted in the upper plenum to save space, and the enclosures have low installation costs and require no outside ducting. Systems also provide quiet operation as low as 45 dBA, depending on face velocity.

Supplier: 3M Food Safety

The Neogen® Petrifilm® Plate Reader Advanced enumerates 11 different Neogen® Petrifilm Plates: Rapid Aerobic Count Plate, Rapid Coliform Count Plate, Rapid E. coli/Coliform Count Plate, Rapid Yeast and Mold Count Plate, Aerobic Count Plate, Coliform Count Plate, Enterobacteriaceae Count Plate, E. coli/Coliform Count Plate, Select E. coli Count Plate, Staph Express Count Plate, Staph Express Disk, and Lactic Acid Bacteria Count Plate.

Supplier: ProSci Inc.

Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains each ~200,000 daltons, and four light chains each ~16,000 - 21,000 daltons. Activation of smooth and cardiac muscle primarily involves pathways that increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. The selected peptide sequence used to generate the polyclonal antibody is located near the amino terminal end of the polypeptide corresponding to the smooth/non-muscle form of myosin regulatory light chain found in cardiac myocytes in addition to smooth and non-muscle cells. This sequence differs from that of the sarcomeric/ cardiac form of myosin regulatory light chain that has a different sequence around the phosphorylation site. Human, mouse and rat have almost identical sequences.

Supplier: VACUUBRAND

Package for fine vacuum control with CVC 3000 and VACUUVIEW extended for KF DN 16, with in-line isolation valve VV-B 15C, T-piece, hose nozzle DN 10 and connecting parts, certification (NRTL): C/US 100-230 V/50-60 Hz, plug CEE/CH/UK/US/AUS 1 * 1 items

Supplier: ERLAB CAPTAIRE

The Captair® Smart filtering chemical storage cabinets are designed with a simple and innovative way of communication. Smart Technology uses simple light to show that the unit is operating safely so the user can focus his attention on what is most important: his work. Smart Technology enables visual light to indicate the hood status. A simple light pattern indicates if the air flow is compromised, if there is a fan failure, a filter breakthrough or if the doors are open.
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Supplier: Heidolph Instruments GmbH & Co.KG

Hei-VAP Industrial large scale rotary evaporators for enhanced vacuum control standards and for maximum safety.

Supplier: Biosepar

ParasiTrap® enables detection of worm eggs, protozoa and larvae. The ParasiTrap® is a transport and testing system for the parasitological examination of stools in human and veterinary medicine. It is a completely closed system with 4 simple steps to make the diagnosis: 1. load tube with sample; 2. add solvent and stain; 3. filter and concentrate; 4. examine under microscope. It was developed to facilitate the unpleasant task of processing infectious stools in laboratory environments, reduce risk of infection and ensure the best possible yield of parasites. The closed system also allows macroscopic diagnostic procedures to be performed where necessary. This diagnostics concept fully complies with the modern quality management criteria of national and international guidelines (EU, CDC, WHO, BGA, DPG). All systems are free of merthiolate and ether. The ParasiTrap® AF-System contains a filled processing and transport tube I (with Medium AF) and the processing tube II with integrated stainless steel filter system. Accessories: separation medium B, staining solution medium C, Pasteur pipettes (disposable), spoons and cotton wool sticks. Additional screw caps for processing tube II.

Supplier: Priorclave

These autoclaves combine a huge internal capacity with a small floor area and are ideally suited for use in a wide range of sterilising applications such as media preparation, liquids and diluent, waste, glassware, instruments and apparatus. They are extensively used within many industries, including food, drink, dairy, pharmaceutical, agricultural, education, healthcare, research establishments and industry. All Priorclaves come complete with Biomaster antimicrobial coating, helping improved laboratory hygiene; it is effective against all bacteria and fungi including MRSA and therefore helps minimise the risk of cross contamination.

Supplier: ProSci Inc.

Notch is synthesized in the endoplasmic reticulum as an inactive form which is proteolytically cleaved by a furin-like convertase (S1 cleavage) in the trans-golgi network before it reaches the plasma membrane to yield an active, ligand-accessible form. Cleavage results in a C-terminal fragment N(TM) and a N-terminal fragment N(EC). Following ligand binding, it is cleaved (S2 cleavage) by TNF-alpha converting enzyme (TACE) to yield a membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). This fragment is then cleaved by presenilin-dependent gamma-secretase (S3 cleavage) to release the intracellular domain (NICD) from the membrane. Notch functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

Supplier: ProSci Inc.

TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25 kDa homodimer composed of two 12.5 kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.