4942 Results for: "Methanol"

Supplier: MP Biomedicals

Sodium 1-heptanesulfonate is a commonly used ion pairing reagent for HPLC, including analyses of peptides and proteins. It has also been used in high performance capillary electrophoresis analysis of peptides.

Supplier: Enzo Life Sciences

Immunomodulating mycotoxin which acts by blocking membrane thiol groups. Inhibits the chymotrypsin-like activity of the 20S proteasome in a non-competitive manner. Causes apoptotic cell death in macrophages and thymocytes. Induces Ca2+ release from intact rat liver mitochondria. Inhibits the activation of transcription factor NF-κB in response to a variety of stimuli in T and B cells. Displays anti-inflammatory activity in vivo. Antioxidant. Inhibitor of farnesyltransferase and geranylgeranyltransferase I. A negative control analog is available. Displays anti-tumor activity against breast cancer in vivo.

Supplier: MP Biomedicals

p-Nitrophenyl Acetate used with iodoacetic acid for reductive cleavage of methionine-containing peptides. It is also used as a substrate that has been used in assays for esterase and lipase activity. Inorganic complexes have been evaluated for their methanolysis or hydrolysis activity using p-nitrophenyl acetate.

Supplier: Thermo Fisher Scientific

Silver protein is used in electron microscopy with periodic acid and thiocarbohydrazide or thiosemicarbohydrazide as a positive stain for carbohydrates such as glycogen. It can also be used for light microscopy to stain nerve tissue. It is also used in histological stain for microscopic analysis.

Supplier: EDVOTEK

This experiment introduces a simple method to determine protein subunit molecular weights using horizontal electrophoresis. As the protein standards and 'unknowns' are prestained, the separation of proteins can be observed during electrophoresis. Included in the experiment is protein-grade agarose, which provides an alternative to the use of polyacrylamide gels.

Supplier: MP Biomedicals

A phase transfer catalyst ideal for the precipitation of DNA

Supplier: MP Biomedicals

Methyl p-Hydroxybenzoate is the methyl ester of p-hydroxybenzoic acid. Typically used as a preservative in foods, beverages and cosmetics.

Supplier: MP Biomedicals

Minocycline hydrochloride (INN) is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group. It is a bacteriostatic antibiotic, classified as a long-acting type.

Supplier: MP Biomedicals

Rifampin is a bactericidal antibiotic drug of the rifamycin group. It specifically inhibits DNA-dependent bacterial RNA Polymerase. Mammalian RNA polymerase is not affected.

Supplier: MP Biomedicals

L-Phenylalanine is one of the 20 amino acids. It is an essential amino acid. It contains an aromatic side chain, which contributes to ultraviolet absorbance and fluorescence properties.

Supplier: MP Biomedicals

Doxorubicin Hydrochloride is a chemotherapeutic, antitumour, immunosuppressive, and antibiotic agent.

Supplier: MACHEREY-NAGEL

Silica based reversed phase materials with polymerically bonded alkyl chains that has exclusively hydrophobic interactions for RP chromatography seperation of biological macromolecules.

Supplier: Restek

These Ultra biphenyl columns are made of high-purity, type-B silica that minimises activity and creates high-density bonding. These columns are designed for selective and reliable HPLC applications.

Supplier: MP Biomedicals

2-Hydroxy-1-(2-hydroxy-4-sulfo-1-naphthylazo)-3-naphthoic acid is a useful indicator for calcium titrations with EDTA in the presence of magnesium.

Supplier: MP Biomedicals

Coomassie Blue R-250 is a triphenylmethane dye used extensively in SDS-PAGE for the analysis of proteins.

Supplier: MP Biomedicals

2-Methylisothiazolone (MIT) are chemical compounds used as highly effective biocidal agents against fungal and bacterial species. They are widely used as a preservative in cosmetic industry, and as a pesticide, e.g. in paints and water tanks.

Supplier: MP Biomedicals

Dimethyl sulfoxide is a dipolar, aprotic solvent. Has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination.

Supplier: MP Biomedicals

Thenoyltrifluoroacetone is used as a reagent for the extraction and spectrophotometric determination of metals, actinides and lanthanides. A metal ion chelator that acts as an inhibitor of electron transport complex II in the mitochondrial respiratory chain. Also acts as an inhibitor of succinate and maleate dehydrogenases.

Supplier: VARIAN

Microsorb™ C18 is an octadecylsilane-covered silica that has been bonded using monofunctional bonding agents under optimised conditions. This material is then endcapped with trimethylsilyl groups to minimise nonspecific binding, maximise mass recoveries and improve peak shape.

Supplier: MP Biomedicals

Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids.

Supplier: MP Biomedicals

ε-Amino-n-caproic acid is a plasmin inhibitor. It inhibits carboxypeptidase B. It promotes rapid dissociation of plasmin by inhibiting the activation of plasminogen. As an inhibitor of plasmin it is has been utilised in the clotting buffer for fibrinogen assays.

Supplier: MP Biomedicals

Synthetic Bactericidal Antibiotic. A structural analog of D-Alanine. A partial agonist at the glycine modulatory site of NMDA receptors; enhances learning and memory in several models of cognitive deficit; anticonvulsant (at high doses). Antibiotic against gram-negative bacteria that acts by inhibiting the synthesis of the cell wall (D-Ala peptide bond formation).

Supplier: Enzo Life Sciences

Inhibitor of the JNK/p38 pathways. Inhibits anisomycin-induced but not TNF-induced JNK/p38 activation. Potent protein kinase inhibitor
>A naturally isolated cell-permeable fungal resorcylic lactone that acts as a selective and highly potent inhibitor against the MAPKKK TAK1 activity (IC50 = 8nM) in an ATP-competitive and irreversible manner; also inhibits MEK1 (IC50 = 411nM) and three other MAPKKKs (IC50 ≥268 nM against MEKK1, ASK1, and MEKK4) but at much higher concentrations. Shown to inhibit IL-1-induced/TAK1-mediated, but not H2O2-induced/TAK1-independent, JNK and p38 phosphorylation in 293 cells.

Supplier: Enzo Life Sciences

PD-98059 is a potent and selective inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK thereby inhibiting the phosphorylation and the activation of MAP kinase. PD-98059 is cell permeable. In PC12 pheochromocytoma cells, it completely blocked the increase in MAP kinase activity produced by NGF, IC50=2µM. Enhances self-renewal of embryonic stem cells PD-98059 is an invaluable tool to help elucidate the role of the MAPK cascade in a variety of biological systems. Inhibits cell growth and proliferation in acute myelogenous leukemia cell lines by causing cell arrest.

Supplier: Enzo Life Sciences

Anabaenopeptins are a highly diverse group of bioactive peptides produced by several genera of cyanobacteria such as Anabaena, Planktothrix, Microcystis and Nodularia. These peptides are commonly detected in cyanobacterial blooms along with the well known microcystins. Unique cyclic peptides where lysine is conserved in position 2 and cyclisation is achieved by linkage of the lysine to the C-terminal amino acid. In addition the side chain of a single amino acid is attached via a ureido bond. Bioactive peptides originally isolated from Anabaena flos-aquae NRC 525-17 where they were shown to be non-toxic in mice but had dose dependant relaxations in rat aortic preparations with endothelium precontracted with 0.1µM norpinephrine.
Anabaenopeptins inhibit protein phosphatase.

Supplier: EDVOTEK

Using prestained LyphoProteins, subunit molecular weights are determined by analysis using denaturing SDS vertical polyacrylamide gel electrophoresis. Prestained proteins with unknown molecular weights are assigned molecular weights based on the relative mobility of prestained standard protein markers.

Supplier: MP Biomedicals

AEBSF hydrochloride is a covalent binding serine protease inhibitor, belongs to the family of irreversible sulphonyl fluoride inhibitors that block trypsin and chymotrypsin-type enzymes.

Supplier: MP Biomedicals

Phenazine methosulfate is an electron acceptor and carrier in enzyme systems. The oxidised form is yellow and the reduced form is colourless.

Supplier: Cytiva

SDS is an ionic detergent used to solubilise proteins. The PlusOne™ SDS reagent is carefully controlled for carbon chain length and overall quality.

Supplier: Thermo Fisher Scientific

Phorbol-12-myristate-13-acetate 95%