146392 Results for: "Manganese+(II)+iodide&pageNo=10&view=list"

Supplier: MP Biomedicals

Storage: Store at +4 °C, store under nitrogen
Glutathione is the major low molecular weight thiol compound of the living plant or animal cell. It is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. The sulfhydryl (thiol) group (SH) of cysteine serves as a proton donor and is responsible for the biological activity of glutathione.
Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Supplier: Thermo Fisher Scientific

Thermo Scientific Pierce DSP (Lomant's Reagent) is a water-insoluble, homo-bifunctional N-hydroxysuccimide ester (NHS ester) crosslinker that is thiol-cleavable, primary amine-reactive, and useful for many applications. DSP contains an amine-reactive NHS ester at each end of an 8-carbon spacer arm. NHS esters react with primary amines at pH 7–9 to form stable amide bonds and releasing N-hydroxy-succinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS ester crosslinking reagents. DSP is non-sulfonated and insoluble in water, so it must first be dissolved in an organic solvent and then added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and so useful for intracellular and intramembrane conjugation. A sulfonated analog of DSP (DTTSP) is water soluble. DSS, the non-cleavable analog of the DSP crosslinker is also available for applications that require a stable spacer arm that cannot be cleaved in the presence of reducing agents.

Supplier: MP Biomedicals

SPINeasy DNA Kit for plant is a silica-membrane spin-column kit that enables quick, convenient and cost-effective isolation of genomic DNA (gDNA) from various plant tissues, such as leaf, stem and seed.

Supplier: OMEGA BIO-TEK

RNA-Solv® Reagent is a one reagent system for the isolation of total RNA from cells and tissues. The reagent, a single-phase solution consisting of phenol and guanidine isothiocyanate, is a modification of the single-step RNA isolation method developed by Chomczynski and Sacchi. The sample is homogenised and lysed in RNA-Solv® Reagent, which maintains the integrity of the RNA while disrupting and denaturing endogenous RNases and other cellular components. Extraction of the lysate with chloroform further denatures proteins and separates the mixture into an organic and an aqueous phase. RNA remains exclusively in the aqueous phase, and is subsequently recovered by isopropanol.

Supplier: Merck

L(+)-Histidine monohydrochloride monohydrate, Millipore®

Supplier: Testo

Testo 871s thermal imager together with our experienced professionals to enable you to work quickly and easily with professional thermal imaging technology. Generates error-free and objectively comparable infrared images using its handy functions. The IFOV warner, testo ɛ-Assist and testo ScaleAssist mean can avoid measurement errors and not only effortlessly achieve optimum setting of emissivity (ɛ) and reflected temperature (RTC) for building thermography, but also of colour scale. This combines high infrared resolution with professional measuring performance and easy handling. Its high-quality pixel detector, an integrated digital camera and, last but not least, the innovative functions are the features that impress. The testo Thermography App enables the testo 871s to offer smart thermography to meet professional requirements in industry and trade. The case supplied with the thermal imager means it can be conveniently transported.

Supplier: LAUDA

The compact Variocool circulating chillers are ideal for demanding temperature control tasks in laboratories, mini plants and production. The units have a colour TFT screen and membrane keyboard, a USB interface and an integrated alarm which are easily accessable on the front of the unit. They also feature an electronic fill gauge on the display and low fluid level alarm. Models can be either air or water cooled, all have lockable castors. A wide range of factory fitted options and interfaces which can be retrofitted give the user greater flexibility and control. Options include high power pumps to allow higher supply pressure, heaters adapted to the cooling capacity to enable rapid heating as required, flow control, outdoor installation, use with deionised water and noise reduction. Optional interfaces including analogue module, RS232/485, contact modules, profibus and PT100/LiBus modules are all available to facilitate customisation of the unit to applications. For details of the options and interfaces, please contact your local Avantor sales office.

Supplier: Corning

Axygen power supplies are ideal for most electrophoresis needs.

Supplier: ProSci Inc.

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (1). Eight members of HDAC family have been identified in the past several years (2,3). These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns (3). These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo. HDAC8 interacts with PEPB2-MYH11, a fusion protein consisting of the 165 N-terminal residues of CBF-beta (PEPB2) with the tail region of MYH11 produced by the inversion Inv(16)(p13q22), a translocation associated with acute myeloid leukemia of M4EO subtype. The PEPB2-MYH1 fusion protein also interacts with RUNX1, a well known transcriptional regulator, suggesting that the interaction with HDAC8 may participate to convert RUNX1 into a constitutive transcriptional repressor.

Supplier: MP Biomedicals

SPINeasy PCR purification and gel extraction Kit is a silica-membrane spin-column kit that enables quick and convenient DNA clean up from various enzymatic reactions, such as PCR and restriction digestion, as well as isolation and purification of DNA fragments from agarose gel electrophoresis.

Supplier: Thermo Fisher Scientific

GeneJET Gel Extraction Kit is designed for rapid and efficient purification of DNA fragments from standard or low-melting point agarose gels run in either TAE or TBE buffer.

Supplier: NEW PIG

Prevent slips, trips and falls in high traffic areas with our easy to clean, adhesive backed commercial floor mat.

Supplier: Cytiva

Sephadex™ G-50 M DNA Grade chromatography resin for purification of DNA fragments up to 20 bases in length from small molecules such as salts by size exclusion.

Supplier: OMEGA BIO-TEK

Isolate plasmid DNA from up to 5 ml culture in 9 minutes utilizing an innovative lysate clearance column.

Supplier: VWR Collection

This 'two in one' lab water system produces ultrapure (Type I) and RO (Type III) water from tap water. Quality of ultrapure water meets or exceeds ASTM, CLSI, CAP, and ISO Type I water standards.

Supplier: MP Biomedicals

The SPINeasy® RNA Kit for Feces delivers high yields of pure RNA without detectable DNA contamination in less than 20 min, making it particularly suitable for downstream applications, such as qPCR and RT-qPCR without the need of further inhibitor/DNA removal steps.

Supplier: ProSci Inc.

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. COX10 is heme A: farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: Quantabio

The Extracta™ DNA prep for PCR - tissue consists of a two component reagent kit for rapid and efficient extraction of PCR-ready genomic DNA from mammalian tissues. The kit has been demonstrated to work with mouse tail biopsies, ear punches and a variety of human tissue samples including hair, buccal cells and saliva.

Supplier: MP Biomedicals

SPINeasy® DNA Kit for Microbiome employs a novel method for isolating microbial genomic DNA from various samples. Due to its highly effective lysis capability and silica-membrane spin-column technology, the SPINeasy® DNA Kit for Microbiome can be used for bacterial, body fluids and environmental samples such as soil and stool.

Supplier: MACHEREY-NAGEL

Reagent case-new design-for determination of temperature, pH 4-9, alkalinity, oxygen, total hardness, ammonium, nitrite, phosphate w ith ECO- and titration test kits VISOCOLOR. 1 * 1 SET

Supplier: VACUUBRAND

These chemistry vacuum systems can be used in a wide range of applications for evacuating or moving gases and vapours between containers in chemistry and physics laboratories, e.g. as an alternative to water jet pumps and rotary vane pumps. Compact construction, very quiet running, long service life, diaphragm and valves are very easy to replace. Oil-free vacuum.

Supplier: OMEGA BIO-TEK

Purify endotoxin free (<0,1 EU/µg) plasmid DNA using magnetic beads from up to 50 ml culture volume.

Supplier: G-Biosciences

GET™ CLEAN DNA uses high binding affinity GET™ spin columns to remove salts, enzymes, unincorporated nucleotides, radiolabels, and primer-dimers from any DNA preparation of 100 bp to 20 kb. GET™ spin columns has an enhanced binding affinity for DNA, thus eliminating loss or damage of DNA.

Supplier: Cytiva

Sephadex™ G-100 DNA Grade is ideal for use in preparing spin columns for DNA purification.

Supplier: Testo

The testo 872s thermal imager is ideally suited for professional industrial and building thermography at the same time it ensures your work is both quick and easy. It is versatile to use, for example in industrial and mechanical maintenance or for detecting structural defects. Generates error-free and objectively comparable infrared images using its handy functions. The IFOV warner, testo ɛ-Assist and testo ScaleAssist mean can avoid measurement errors and not only effortlessly achieve optimum setting of emissivity (ɛ) and reflected temperature (RTC) for building thermography, but also of thermal image scale. This gives the best possible support for your work in professional industrial and building thermography. Take thermal images quickly, reliably and smartly with the highest image quality, very good thermal sensitivity and innovative functions. The case supplied with the thermal imager means it can be conveniently transported

Supplier: MP Biomedicals

The GeneClean® Turbo for PCR Kit removes primers, nucleotides, enzymes, mineral oil, salts, and other impurities from DNA samples. DNA fragments purified with this kit are ready for direct use in all applications, including sequencing, microarray analysis, ligation and transformation, restriction digestion and labeling.

Supplier: Thermo Fisher Scientific

di-Sodium L(+)-tartrate dihydrate 99+% ACS

Supplier: Cytiva

The ExoProStar™ S PCR and Sequence Reaction Clean-Up Kit updates existing enzymatic PCR clean up technology with Exonuclease I and Shrimp Alkaline Phosphatase to remove unincorporated primers and dNTPs. illustra ExoProStar™ S improves digestion efficiency with no degradation of the target PCR product. Sample remain completely intact and ready for immediate use in manual or automated processes. For maximum flexibility the enzymes are supplied in two separate tubes.

Supplier: Cytiva

Sera-Xtracta virus/pathogen kit for high-throughput total nucleic acid (DNA/RNA) isolation from bacteria and viruses including adenovirus (type 14), influenza A (H3N2) and COVID-19.

Supplier: ProSci Inc.

F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.