Supplier: EPPENDORF

Eppendorf epT.I.P.S.® Reloads offer high-precision pipette tips in 'Eppendorf Quality' and 'PCR clean' purity grades. Eco-friendly, cost-effective, and designed for seamless compatibility with Eppendorf Box 2.0, they ensure accuracy and sustainability in labs.

Supplier: SIOEN

This multifunctional, water- and wind-proof garment consists of a light rain jacket in a very breathable material and a smart softshell jacket with detachable sleeves. Made from highly breathable Siopor® Ultra fabric consisting of 100% polyester with 100% PU coating, with fixed mesh lining and knitted wind cuffs in the sleeves.

Supplier: FRISTADS KANSAS

These high visibility trousers are made of 54% modacrylic, 44% cotton and 2% anti-static fibre. Reinforced with 79% cotton FR, 20% polyamide, 1% anti-static fibre. They provide protection against chemicals, heat, flames and electric arcs.

Supplier: Thermo Fisher Scientific

Thermo Scientific Slide-A-Lyzer™ G3 Dialysis Cassettes facilitate the rapid and trouble-free dialysis of sample volumes from 0,5 to 125 ml. Unlike standard flat tubing, these innovative devices do not require knots or clips that can lead to leaking and sample loss.

Supplier: LAUDA

TUBE CONNECTOR 8-10 ON 4-8 MM 1 * 1 items

Supplier: Cayman Chemical

11Β-PROSTAGLANDIN F2Α-D9 1 * 100 µG

Supplier: GRANT INSTRUMENTS

High quality, digital unstirred water bath range with choice of models from 2 to 34 litres and a dual bath with 5 and 12 litres. Dual baths are ideal when two different temperatures are needed and space is limited. All units have stainless steel tanks and durable painted steel cases, offer fast heat-up times, excellent temperature control, easy to use controls and a bright, clear display. All baths have heater mat technology ensuring optimum working space, without a heating element in the tank they are easier to clean. The 12 litre and larger models feature a convenient drain tap on the front of the bath. The range is ideal for use in university research and teaching, pharma/biotech, healthcare and industrial applications.

Supplier: Thermo Scientific

Ideal for routine processing, these centrifuges combine exceptional capacity, ergonomics, and value with market-leading capabilities including unparalleled productivity and throughput, as well as exceptional ergonomics.

Supplier: Bioss

ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.

Supplier: EJENDALS

Tegera Gloves 48, Chemical Protection, Nitrile 0.60mm, unflocked, diamond grip pattern, green, length 450mm, Cat III, AQL 0.65 1 * 1 PAIR

Supplier: Thermo Scientific

Process a range of general-purpose applications including cell culture, microplate, bioproduction, blood separation, and microbiology with the Thermo Scientific™ Multifuge™ X4 Pro centrifuge series featuring new touch screen technology, making daily tasks easier.

Supplier: Quantabio

Ultra-Plex™ 1-Step ToughMix® is a ready-to-use, 4X-concentrated master mix for reverse transcription quantitative PCR (RT-qPCR) of RNA templates using hybridisation probe detection chemistries such as TaqMan® 5’-hydrolysis probes on Real-Time PCR systems that utilise ROX passive reference with 490 nM excitation. First-strand cDNA synthesis and PCR amplification are carried out in the same tube without opening between procedures. It is ideal for highly sensitive quantification of RNA viruses or low abundance RNA targets in uni- or multiplexed RT-qPCR applications as well as high throughput gene-expression studies. The system has been optimised to deliver maximum RT-qPCR efficiency, sensitivity, and specificity in reduced reaction volumes and fast cycle times. Ultra-Plex™ 1-Step ToughMix® contains all required components for RT-qPCR except RNA template and probe. It is compatible with all dual-labeled probe chemistries.

Supplier: Bioss

DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.Tissue specificity: Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, and pancreas. Very low expression seen in the brain. Expressed in dividing cells and/or cells undergoing high levels of recombination. No expression is seen in cells signaled to terminally differentiate. Expressed in keratinocyte growth factor-stimulated cells but not in serum, EGF and IL1-beta-treated keratinocytes.

Supplier: Portwest

This jacket offers exceptional weather protection, comfort, and warmth while utilising the latest innovations in recycled fabrics. The outer shell, lining, and wadding are certified recycled polyester, and the packaging is derived from sugarcane, allowing the wearer to champion sustainability without compromising on performance.

Supplier: HAMILTON BONADUZ

The 1000 series is a mid volume Gastight® syringe. Gastight® syringes are ideal for dispensing both liquids and gases. They have a precision machined PTFE plunger tip which creates a leak-free seal. With the tight fit, the tip essentially wipes the interior of the syringe barrel free of sample. This feature is particularly useful with heterogeneous samples as it reduces the chance that a deposit will occur and cause the plunger to freeze.

Supplier: Portwest

These multi use high visible bodywarmer vests are specially designed for those who will not compromise on style, comfort, protection and performance. These garments are designed to keep warm, dry and visible in all conditions. The 300D Oxford Industry High Visibility provides comprehensive range of single and combination garments in a highly durable and cleverly designed innovative styles.

Supplier: Corning

PS, sterile. The Corning® CellSTACK® culture chambers are available in five sizes and with three different surface treatments.

Supplier: ProSci Inc.

Interleukin-33 (IL-33) was initially discovered as a nuclear factor NF-HEV abundantly expressed in high endothelial venules. It is a 30-32 kD pro-inflammatory protein with intracellular and extracellular activities and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 is highly and selectively expressed by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. It contains a bipartite nuclear localization signal at the C-terminus, and is targeted to the nucleus when ectopically expressed in human umbilical vein endothelial cells (HUVECs) and HeLa cells. The C-terminal fragment, corresponding to mature IL-33, binds and triggers signaling. IL-33 mediates its biological effects via Toll-interleukin 1 (IL-1) receptor (TIR) domain-containing receptor ST2, activates NF-kappaB and MAP kinases, and drives production of T(H)2-associated cytokines from in vitro polarized T(H)2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. Human IL-33 is 270 amino acids in length.

Supplier: KARTELL

CAP RUBBER 12/15X18MM RED 1 * 1 items

Supplier: Cayman Chemical

11Β-PROSTAGLANDIN F2Α-D9 1 * 50 µG

Supplier: IKA

Cable PC1.1 1 * 1 items

Supplier: Hettich

ADAPTER FOR 12X1.1-6 ML TUBE IN 5092 1 * 1 items

Supplier: LAUDA

TUBING ARMAFLEX TYPE:D 10 1 * 1 m

Supplier: Cytiva

rProtein A Sepharose™ 4 Fast Flow is a well established antibody affinity medium is designed for the purification of monoclonal and polyclonal antibodies based on Sepharose™ Fast Flow platform. The recombinant protein A is produced in E.coli and engineered for an oriented coupling to giving a matrix with enhanced binding capacity. The epoxy-based coupling ensures low ligand leakage. The specificity of the recombinant protein A for the Fc region of IgG is similar to native protein A and provides excellent purification in one step. The high capacity, low ligand leakage and a well established base matrix makes rProtein A Sepharose™ Fast Flow ideal for purification of monoclonal antibodies at both laboratory and process scale.

Supplier: G-Biosciences

The use of peptides for the generation of antibodies against specific peptides has become an essential tool in proteomic research. A crucial step in using peptides as antigens is their coupling to carrier proteins. Peptides are designed to be good epitopes by themselves; however they fail to elicit a strong antibody response. The reason for this is that the epitopes are able to bind to the B-cells, but are too small to contain additional motifs required to associate with class II molecules and T-cell receptors. The carrier proteins, once coupled to the peptides, provide these additional motifs and generate a strong antibody response. All three carrier proteins are also offered as activated carrier proteins, named as ActiveHOOK™.

Supplier: SARSTEDT

S-MONOVETTE COAGULATION 3.0ML 66X11MM 1 * 500 items

Supplier: KNAUER

M1304 seal 1 * 1 items

Supplier: MICRONOVA

PIPEPLUNGER POLYESTER 7.62X12.7CM IRR. 1 * 12 items

Supplier: SARSTEDT

Demeter-Pipette 1,1ml 1 * 1.000 items

Supplier: Resonac

Joint (in) 1 * 1 items