145202 Results for: "Magnesium+nitrate+hydrate&pageNo=10&view=list"
Large laboratory glasswashers, PLW 8617
Supplier: MIELE
The PLW 8617 large laboratory glasswasher can accommodate 216 laboratory flasks, 588 vials, or 294 pipettes. The large glasswasher is flexible and simple to use, it has modular load carriers and EasyLoad system. This efficient unit has a single door, 1150 mm wide, a usable capacity of 351 litres. PLW 8617 provides reliable results, high pump performance with a variable-speed pump and features spray arm monitoring and a conductivity meter.
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Anti-TrpV1 Mouse Monoclonal Antibody [clone: BS397]
Supplier: Biosensis
The capsaicin receptor (VR1, TRPV1) is a ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. The receptor seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. It is involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca2+-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH less than 6) directly activate the channel. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (Ref: uniprot.org).
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ESTRIOL IMP. F (EP):16-EPI-ESTRIOL 1 * 100 mg
Supplier: LGC Standards PROMOCHEM
ESTRIOL IMP. F (EP):16-EPI-ESTRIOL 1 * 100 mg
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Cubis® II MCA 225S Ultra-High Resolution Semi-Micro Balances
Supplier: Sartorius Balances
The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.
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Large laboratory glasswashers, PLW 8615
Supplier: MIELE
The PLW 8615 large laboratory glasswasher can accommodate 216 laboratory flasks, 588 vials, or 294 pipettes. The large glasswasher is flexible and simple to use, it has modular load carriers and EasyLoad system. This efficient unit has a single door, 900 mm wide, a usable capacity of 351 litres. PLW 8615 provides reliable results, high pump performance with a variable-speed pump and features spray arm monitoring and a conductivity meter.
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Volumetric flask, PMP, class B, with stopper NS 12/21, PP, 50 mL 1 * 2 items
Supplier: VITLAB
Volumetric flask, PMP, class B, with stopper NS 12/21, PP, 50 mL 1 * 2 items
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titanium probe TS 106, titanium probe, dia. 6 mm, for HD 4050/4100/4200 1 * 1 items
Supplier: BANDELIN-ELECTRONIC
titanium probe TS 106, titanium probe, dia. 6 mm, for HD 4050/4100/4200 1 * 1 items
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WHM12019,Aℓ-case Heating Mantles with Controller, 450℃, for 10,000ml Spherical flask(DU) 1 * 1 items
Supplier: witeg Labortechnik
WHM12019,Aℓ-case Heating Mantles with Controller, 450℃, for 10,000ml Spherical flask(DU) 1 * 1 items
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Valve discharge for DURAN Group dispenser PRO 2,5/5/10ml (PFA/Borosilicate glass/Platin-Iridium) 1 * 1 items
Supplier: DWK Life Sciences
Valve discharge for DURAN Group dispenser PRO 2,5/5/10ml (PFA/Borosilicate glass/Platin-Iridium) 1 * 1 items
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Volumetric flask, PP, class B, with screw cap, PP, 100 mL 1 * 2 items
Supplier: VITLAB
Volumetric flask, PP, class B, with screw cap, PP, 100 mL 1 * 2 items
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Syringe 10ml 20Gx1 inch Luer-Lok 1 * 400 items
Supplier: BD Medical
Syringe 10ml 20Gx1 inch Luer-Lok 1 * 400 items
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Montage® SEQ96 Sequencing Reaction Cleanup Kits
Supplier: Merck
The Montage® SEQ96 sequencing reaction cleanup kit provides the filtration plate and solution necessary to remove contaminating salts and unincorporated dye terminators from DNA sequencing reactions.
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Analytical balances, Entris® II advanced
Supplier: Sartorius Balances
Entris® II Advanced analytical balances feature isoCAL, intuitive graphic touch display and 13 built-in applications. Highly accurate results are guaranteed via the monolithic weigh cell technology. High chemical resistance is ensured by using parts made from hard-wearing PBT, stainless steel and glass. Integrated protection systems increase reliability of weighing results: Three configurable levels determine valid weighing data and ensure only valid data is transferred to external devices.
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flat bottom glass 36x1,4x120mm 54mm with ring mark fused straight bottom ca.45ml ring mark mark at 54+-0,5mm inside measured straight bottom straight rim fused (pour point glass ) from Boro 3.3 1 * 1 items
Supplier: NEUBERT VOLUME GLASSWAERE
flat bottom glass 36x1,4x120mm 54mm with ring mark fused straight bottom ca.45ml ring mark mark at 54+-0,5mm inside measured straight bottom straight rim fused (pour point glass ) from Boro 3.3 1 * 1 items
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Tip pipette 10µl hinged rack certified sterile 1 * 960 items
Supplier: USA SCIENTIFIC PLASTICS
Tip pipette 10µl hinged rack certified sterile 1 * 960 items
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VOL.FLASK 20ML NS10/19 AMBER POLYSTOPP A 1 * 1 items
Supplier: HIRSCHMANN
VOL.FLASK 20ML NS10/19 AMBER POLYSTOPP A 1 * 1 items
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VISCOTESTER IQ PACK FOR PASTES TM-PE-P 1 * 1 SET
Supplier: HAAKE
VISCOTESTER IQ PACK FOR PASTES TM-PE-P 1 * 1 SET
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L(+)-Lysine monohydrochloride
Supplier: MP Biomedicals
Storage: Store at room temperature (15-30 °C)
L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine. L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.
L-Lysine monohydrochloride is a key amino acid in calcium absorption.
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Human recombinant IL18 (from E. coli)
Supplier: ProSci Inc.
Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesised as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.
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L-Arginine hydrochloride 98.5-101.0% (by perchloric acid titration), EMPROVE® EXPERT Ph. Eur., BP, JP, USP suitable for use as excipient, SAFC®
Supplier: MERCK PRODUCTION CHEMICALS
L-Arginine hydrochloride 98.5-101.0% (by perchloric acid titration), EMPROVE® EXPERT Ph. Eur., BP, JP, USP suitable for use as excipient, SAFC®
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TSKgel® gel filtration columns, SW-type
Supplier: TOSOH BIOSCIENCE
TSKgel® SW size exclusion columns are widely used for aqueous analysis and isolation of proteins, antibodies, enzymes, nucleic acids and other biological macromolecules.
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Refrigerated/heating circulating baths, ecocool™ series
Supplier: GRANT INSTRUMENTS
A range of eco-friendly, refrigerated/heating circulating baths with an intuitive user-interface and sleek design. Units offer significant running cost savings whilst delivering powerful cooling when needed. Choice of 2 models with temperature range of –25 to +150 °C (model dependent*). Ideal for applications in pharmaceutical, education, industrial and life science areas for use with mini pilot plant reactors, cooling rotary evaporators, replacing running tap water cooling, immersing small samples, photometry, chromatography systems, sample preparation, general cooling, reaction chemistry, temperature control, semi-conductor manufacturing, rheometry, refractometry and electrophoresis cooling.
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Anti-GABRA1 Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.
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Anti-GABRA6 Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.
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Multi-parameter meters (pH/mV/conductivity/ion), bench, SevenExcellence™ S470/S475
Supplier: Mettler - Toledo
These instruments with two or three channels are modularly expandable with additional measurement parameters at any time.
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Cubis® II MCA 125S Ultra-High Resolution Semi-Micro Balances
Supplier: Sartorius Balances
The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.
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SkanIt™ Upgrade package, version 5.0
Supplier: THERMO LABSYSTEMS LIFE SCIENCE
This SkanIt Software upgrade package is specifically designed for Thermo Scientific Fluoroskan, Fluoroskan FL, and Luminoskan microplate readers to enable the use of SkanIt software and USB connection between instrument and PC. The upgrade package is also compatible with the discontinued Fluoroskan Ascent, Fluoroskan Ascent FL, and Luminoskan Ascent microplate readers. SkanIt Software is available in two editions: a research edition for scientists working in life science research and a drug discovery edition with features for compliancy with FDA 21 CFR Part 11. Note: the upgrade package is compatible with Ascent instruments that are equipped with internal software version 2.6.
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Anti-GABRB1 Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor (McKernan et al., 2000; Mehta and Ticku, 1998; Ogris et al., 2004; Pöltl et al., 2003).
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Brefeldin A ≥98%, white powder for molecular biology
Supplier: MP Biomedicals
Storage: Store at -20 °C.
Brefeldin A is a fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. Produced by Penicillium brefeldianum. Blocks binding of the cytosolic coat protein b-COP and ARF to Golgi membranes mediated by protein G. Also blocks protein transportation into post-Golgi compartments. It activates the sphingomyelin cycle. Brefeldin A mediated apoptosis has been observed in human tumor cells.
Brefeldin A reversibly inhibits the intracellular translocation of proteins in eukaryotes, e.g., during transport of proteins to the cell surface for secretion or expression. It has been reported to block the response of cultured cells to cholera toxin. In HepG2 cells, BFA induces two blocks in the secretory pathway; one at the level of the endoplasmic reticulum-Golgi juncture and the other in the trans-Golgi network. Brefeldin A is used in the studies of Brefeldin A-inhibited Guanine Nucleotide-exchange Protein, BIG2, Regulates the Constitutive Release of TNFR1 Exosome-like Vesicles.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.