145730 Results for: "Magnesium+nitrate+hydrate&pageNo=10&view=easy"

Supplier: ProSci Inc.

Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterised by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Supplier: ANTIBODIES.COM

Human IL-36 gamma/IL-1F9 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human IL-36 gamma/IL-1F9 in serum, plasma, and other biological fluids.

Supplier: ANTIBODIES.COM

Human IL-18R beta/IL-18RAP ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human IL-18R beta/IL-18RAP in serum, plasma, and other biological fluids.

Supplier: ANTIBODIES.COM

Mouse ZO1 Tight Junction Protein ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse ZO1 Tight Junction Protein in serum, plasma, and other biological fluids.

Supplier: Merck Millipore (Novagen)

The Overnight Express™ Autoinduction Systems enable regulated protein expression in E. coli, without monitoring the culture or adding inducer during cell growth.

Supplier: MP Biomedicals

p-Nitroblue Tetrazolium Chloride is an NADPH-diaphorase substrate that competitively inhibits NOS (nitric oxide synthase) (IC50 = 3-4 μM). In combination with 5-Bromo-4-chloro-3-indolyl phosphate (BCIP) and an appropriate reaction buffer, Nitroblue tetrazolium forms a substrate for the colorimetric detection of alkaline phosphatase conjugates in a variety of molecular and cell biology techniques.

p-nitro blue tetrazolium is used for the detection of alkaline phosphatase on western blots. It has also been used as a redox indicator for other enzymatic reactions including dehydrogenases, threonine deaminase, glucose-6-phosphate dehydrogenase, phosphofructokinase on polyacrylamide gels, oxidases on polyacrylamide gels, and pentose shunt dehydrogenases. Redox and halfwave potentials have been determined for p - nitro blue tetrazolium. It has also been used as a colorimetric indicator of bacterial infection in blood samples.

Supplier: MP Biomedicals

White Powder, soluble in water or aqueous buffers (50 mg/ml); soluble in 0,01 N Sodium hydroxide (100 mg/ml - clear to slightly hazy, yellowish solution).

Supplier: Portwest

Versatile and comfortable protection against all weather conditions. The detachable fur lining and collar, in combination with the zip-out sleeves, prove this is a superbly adaptable garment. Numerous zipped outer and interior pockets afford excellent personal security. Two-way zip for quick and easy access.

Supplier: SARSTEDT

S-Monovette® is a blood collection system that combines two blood collection techniques – aspiration and vacuum. The S-Monovette® is suitable for all vein conditions and achieves an optimal sample quality, thereby producing the best results. The aspiration technique is a gentle technique for routine blood collection. Using the vacuum technique, a 'fresh' vacuum is always available.

Supplier: ProSci Inc.

This antibody recognises actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. This mAb recognises alpha and gamma isotypes of all muscle groups. Nonmuscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of nonmuscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).

Supplier: ProSci Inc.

GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone. GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by Protein Kinase C modulates the interaction of GAP-43 with actin.

Supplier: ProSci Inc.

There is accumulating evidence to suggest that progesterone plays an essential role in the regulation of growth and differentiation of mammary glands and thus may play a key role in breast cancer. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (A and B forms). In most cell contexts, the B form functions as a transcriptional activator, whereas the A form functions as a transcriptional inhibitor of steroid hormones. Recently it has been demonstrated that there is differential hormone dependent regulation of the phosphorylation of the A and B forms of the receptor. Treatment of T47D breast cancer cells with progestin agonist increases the phosphorylation of Ser190 and Ser294 with different kinetics. These phosphorylation events may differentially affect the transcriptional activity of the receptor.

Supplier: ProSci Inc.

TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to five distinct receptors: TRAIL-R1 (DR4; Apo2; CD261; TNFRSF10A), TRAIL-R2 (DR5; KILLER; TRICK2A; TRICK2B; CD262; TNFRSF10B), TRAIL-R3 (DcR1; LIT; TRID; CD263; TNFRSF10C), TRAIL-R4 (DcR2; TRUNDD; CD264; TNFRSF10D), and osteoprotegerin (OPG; OCIF; TNFRSF11B). Trimerized TRAIL triggers apoptosis upon ligation of cell surface TRAIL-R1 and/or TRAIL-R2 by inducing the formation of the so-called multiprotein death-inducing signaling complex (DISC). .

Supplier: ProSci Inc.

The TNF family ligand ectodysplasin A (EDA) and its receptor EDAR are required for proper development of skin appendages such as hair, teeth, and eccrine sweat glands. Loss of function mutations in the Eda gene cause X-linked hypohidrotic ectodermal dysplasia (XLHED), a condition that can be ameliorated in mice and dogs by timely administration of recombinant EDA. The Eda gene on the X chromosome is transcribed as multiple splice variants, only two of which code for the receptor-binding C-terminal TNF homology domain. These two variants code for 391- and 389-amino acid-long proteins called EDA1 and EDA2. EDA1 binds EDAR, whereas EDA2 binds to another receptor, XEDAR. The biology of EDA2 and XEDAR is distinct from that of EDA1. Indeed, XEDAR-deficient mice have no obvious ectodermal dysplasia phenotype, whereas mice deficient in EDA, EDAR, or the signalling adaptor protein EDARADD all display virtually indistinguishable ectodermal dysplasia phenotypes, indicating the predominance of the EDA1-EDAR axis in the development of skin-derived appendages.

Supplier: SIOEN

These lightweight, breathable trousers made of Siopor® FR AST fabric (100% polyester fabric with 100% FR PU coating + AST) are waterproof and windproof and have anti-static features. The fixed cotton lining is flame-retardant. The trousers provide good tear resistance and protection against rough weather conditions.

Supplier: IKA

Laboratory stirrers designed for simple stirring tasks for quantities up to 15 or 25 L (EUROSTAR 20 digital and EUROSTAR 40 digital), or for intensive stirring tasks for quantities up to 20 L (EUROSTAR 20 high speed digital). Units automatically adjust the speed through microprocessor controlled technology within the speed range of 0/30 to 2000 min⁻¹ (or 0/150 to 6000 for the high speed model). Safety circuits ensure automatic cut off in anti-stall or overload conditions. The actual shaft speed and preset speed are constantly monitored and variations are adjusted automatically. This guarantees a constant speed even with changes in sample viscosities.

Supplier: MP Biomedicals

Dextran sulphate is a polyanionic derivative of dextran produced by esterification of dextran with chlorosulphonic acid. The sulphur content is approximately 17% which corresponds to an average of 1,9 sulphate groups per glucosyl residue of the dextran molecule. Dextran sulphate sodium (DSS) is the sodium salt which is a white to off-white powder freely soluble in water and salt solutions to form a stable, clear solution. The high purity and reproducible quality enables its application in pharmaceuticals and biotechnology industry.

Supplier: LAUDA

Laboratory upright freezers with reliable monitoring and highly efficient insulation for long-term storage and quality assurance of organic substances and other materials.

Supplier: ProSci Inc.

EndoG Monoclonal Antibody: The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribonuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans. EndoG also cleaves DNA in vitro.

Supplier: ProSci Inc.

EndoG Monoclonal Antibody: The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribonuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans. EndoG also cleaves DNA in vitro.

Supplier: ProSci Inc.

ANGPTL4 (Angiopoietin-like protein 4) mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorigenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.

Supplier: EPPENDORF

Eppendorf twin.tec® PCR plates LoBind, available in 96 and 384-well formats, maximize nucleic acid recovery and are certified as 'PCR clean' for consistently reliable results.

Supplier: ANTIBODIES.COM

Human HCF-1/Host Cell Factor C1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human HCF-1/Host Cell Factor C1 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: TECHNICAL SERVICE SPARE PARTS

REFERENCE SCREW 1 * 1 items

Supplier: Hach

8350 Combination pH sensor, 3/4 , analogue, for corrosive media 1 * 1 items

Supplier: LP ITALIANA

CONICAL TUBE WITH LABEL WITH YELLOW CAP 1 * 2.000 items

Supplier: Biochrom

50mm Single Cell Holder 1 * 1 items

Supplier: Thermo Orion

These bench top meters with pH/LogR module meet most challenging applications for pH, mV, ORP and LogR temperature. The meters offer interchangeable measurement modules that allow multiple users to customise four separate channels to meet their specific requirements. The LogR™ technology enables users to measure both pH and temperature using the glass-bulb of most pH electrodes – ideal for small sample volumes and samples that are difficult to clean.

Supplier: CAMAG

GLASS COVER PLATE 143X143X4 FOR HDC 10X10 022.8500/30 1 * 1 items

Supplier: BOCHEM

FORCEP SS 18/8 LENGTH 115MM BLUNT 1 * 1 items