13272 Results for: "Loading+Buffers&pageNo=35&view=list"
Anti-beta Amyloid 1-42 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Supplier: Bioss
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.
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Isoelectric focusing system, Ettan™ IPGphor™ 3
Supplier: Cytiva
Ettan™ IPGphor™ 3 is a fully integrated isoelectric focusing (IEF) system optimised to deliver high throughput, speed, reproducibility, and high protein-loading capacity. Ettan™ IPGphor™ 3 is optimised for easy handling of CyDye™ labelled proteins and other light-sensitive samples, and provides temperature control critical for reproducibility in 2-D DIGE experiments.
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Multi-parameter meters, handheld, HQ series
Supplier: Hach
Robust and intuitive portable meters, instilling confidence in reporting and managing your results.
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Anti-beta Amyloid 1-42 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Supplier: Bioss
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.
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Rotary Evaporators, Hei-VAP Expert Control
Supplier: Heidolph Instruments GmbH & Co.KG
Hei-VAP Expert Control rotary evaporators allow central control of all process parameters: Vacuum, cooling temperature, rotation and heating bath temperature. The units have separate knobs for quick access: Right for direct vacuum control, the left one for rotation has a lock function to prevent accidental adjustment
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DNA purification kits, GeneClean® II kit, MP Biomedicals
Supplier: MP Biomedicals
The GeneClean® II Kit is designed to optimally purify 200 bp to 20 kb DNA from TAE and TBE buffered agarose gels and solutions. The purified DNA is suitable for a variety of downstream applications, such as sequencing, PCR, restriction digestion, cloning and labeling.
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Fast RNA™ Pro Soil-Direct Kit, MP Biomedicals
Supplier: MP Biomedicals
FastRNA™ Pro Soil-Direct Kit is used to isolate total RNA from organic material found in soil samples. The total RNA isolated is suitable for RT-PCR analysis and other downstream applications.
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Microplate readers, Varioskan™ LUX
Supplier: THERMO LABSYSTEMS LIFE SCIENCE
Varioskan™ LUX comes equipped with a range of measurement technologies including absorbance, fluorescence intensity and FRET as standard, and with optional luminescence, AlphaScreen and time-resolved fluorescence (TRF) modules. The instrument selects the measurement wavelength using filters or monochromators, depending on which is optimal for each measurement technology.
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Titrators, Karl Fischer, coulometric, TitroLine® 7500 KF Trace
Supplier: SI Analytics
These very compact, easy to operate instruments are ideal for coulometric water determination according to Karl Fischer in low water content, as well as for bromine number determination. They are suitable for small liquid or gaseous sample amounts, and can be used for quality control in the chemical, petrochemical, pharmaceutical and food industries.
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Tissue Genomic DNA Extraction Kits
Supplier: BIOPREMIER
The tissue genomic DNA extraction Kit is designed for the rapid purification of highly pure genomic DNA from a wide variety of samples, including whole blood, culture cells, animal tissues, mouse tails, bacteria, yeats, clinic samples (serum, plasma, feces, orine), forensic samples and paraffin-embedded tissues.
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Robotic tips (CO-RE Tips) and consumables for Microlab
Supplier: HAMILTON ROBOTICS
Hamilton CO-RE tips were designed for MICROLAB pipetting workstations in order to solve the problem of sealing and alignment plagued by press-fit tip attachment techniques. Each CO-RE disposable tip has a circular groove inside the attachment orifice. An o-ring on the pipetting channel is expanded to fit this groove precisely providing an air-tight seal and straight alignment between tip and pipetting channel.
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EZ-Pak® membrane dispenser curve
Supplier: Merck
The next generation membrane dispenser: Fast, robust, no-touch dispensing.