145766 Results for: "LGC+Standards+PROMOCHEM&pageNo=10&view=list"

Supplier: Air Liquide

These vessels are designed for long term storage of biological samples in straws, cryo-vials and bags. A variety of electronic options on all models rack or canister storage systems for the samples.
Made of aluminum and composite materials.

Supplier: Portwest

Be seen and be comfortable in this excellent quality jacket. The unique lightweight material offers an unrivaled combination of breathability, waterproof, and windproof protection.

Supplier: Portwest

This jacket is made from 300D Oxford Weave fabric (300 denier polyester yarn) which features a high abrasion and tear resistance. The PU coating on the inside makes the fabric durable and waterproof, while the outer has a water- and stain-repellant coating which helps keep the garment clean.

Supplier: HUBER

These circulators with insulated refrigeration baths are designed for direct temperature control from −20 to +200 °C. The units are suitable for a number of typical heating and cooling tasks such as sample temperature control, materials testing, quality control and analyses.

Supplier: EPPENDORF

For any application that requires sample/reaction mixing and heating the Eppendorf® ThermoMixer F family is what you need. Whether you work with 0,5/1,5/2,0 ml tubes or plates (MTP and DWP) the dedicated fixed blocks offer a perfect solution for your special application.

Supplier: Thermo Fisher Scientific

Thermo Scientific EZ-Link Sulfo-NHS-LC-LC-Biotin enables simple and efficient biotin labeling of antibodies, proteins, and any other primary amine–containing macromolecules. Specific labeling of cell surface proteins is another common application for these uniquely water-soluble and membrane impermeable reagents.

Supplier: ProSci Inc.

Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I. Phosphorylation of this site is thought to regulate synaptic vesicle function.

Supplier: ProSci Inc.

ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Supplier: Antibodies.com

Human Scavenging receptor SR-BI ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Scavenging receptor SR-BI in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human Serum Response Factor SRF ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Serum Response Factor SRF in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Mouse Retinoic acid Receptor gamma ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse Retinoic acid Receptor gamma in serum, plasma, and other biological fluids.

Supplier: Antibodies.com

Mouse PGC1 alpha ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse PGC1 alpha in serum, plasma, and other biological fluids.

Supplier: Antibodies.com

Mouse NF-kB p65 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse NF-kB p65 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: ProSci Inc.

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Supplier: ProSci Inc.

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Supplier: Antibodies.com

Mouse ZO1 Tight Junction Protein ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse ZO1 Tight Junction Protein in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human PGC1 alpha ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human PGC1 alpha in serum, plasma, and other biological fluids.

Supplier: Antibodies.com

Human PI 3 Kinase p85 beta ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human PI 3 Kinase p85 beta in serum, plasma, and other biological fluids.

Supplier: ProSci Inc.

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Supplier: ProSci Inc.

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33 to 35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Supplier: ProSci Inc.

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress. Required for the folding of immunoglobulin proteins. Responsible for the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin.

Supplier: Thermo Fisher Scientific

These spin columns provide a fast, easy to use format for purifying GST-fusion proteins from cellular lysates. The glutathione is immobilised through its central sulfhydryl onto 6% crosslinked agarose resin. Purification of GST-fusion proteins using glutathione (GSH) agarose beads is well documented and provides a one-step, high purity affinity purification.

Supplier: ProSci Inc.

TMP21 Antibody: TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport. More recent experiments have shown that it is also a component in the presenilin complex and modulates the gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein. The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1. Together, these proteins cleave the amyloid precursor protein at what is known as the gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer's disease. Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex. Suppression of TMP21 expression by siRNA in transfected cells caused increased gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate gamma-secretase activity.

Supplier: EPPENDORF

Eppendorf Deepwell plates 96-well, 500 µl offer efficient sample handling with features like OptiTrack® matrix for rapid identification and g-Safe® technology for stability during centrifugation. SafeCode variants provide secure three-level coding, including error correction for reliable identification, ensuring flexibility and accuracy in experimental workflows.

Supplier: Honeywell Safety

GLOVE PROCHEM 30CM SIZE 10XL 1 * 12 PAIR

Supplier: Amarell

Metal ferrules, DIN 12787 mounted on Viscometer therm., Vogel-Ossag 1 * 1 items

Supplier: Thermo Fisher Scientific

MODULE FP DIGITAL MCP NEW 0,5-10UL 1 * 1 items

Supplier: Hospidex

SYRINGE 10µL PLUNGER SUPPORT WITH TELESCOPIC PLUNGER FIXED NEEDLE 1 * 1 items

Supplier: Thermo Orion

These bench top meters with with pH and conductivity modules meet the most challenging applications for pH, mV, ORP, conductivity, total dissolved solids (TDS), salinity, resistivity and temperature. The meters offer interchangeable measurement modules that allow multiple users to customise four separate channels to meet their specific requirements.

Supplier: MP Biomedicals

Acetyl-CoA is produced via beta-oxidation of fatty acids, via the metabolism of carbohydrates - glucose 6-phosphate to pyruvate to acetyl-CoA and via the catabolism of amino acids. Acetyl-CoA has a number of metabolic opportunities. It is metabolised in the tricarboxylic acid cycle to produce carbon dioxide, water and energy.