8330 Results for: "L(+)-Potassium+hydrogen+tartrate"

Supplier: Boster Bio

Rabbit IgG polyclonal antibody for KCNA1 detection. Tested with WB, Direct ELISA in Human Mouse Rat. 1 * 100 µG

Supplier: DELTALAB

EDTA TRI-K tibe 3 ml PP 13X75 with perf. rubber cap 20x50(1000 pcs.) 1 * 1.000 items

Supplier: SARSTEDT

Microvette® 500 EDTA K3E, 500 µl, cap violet, flat base 1 * 1.000 items

Supplier: Thermo Orion

This Triode™ electrode has a built-in temperature sensor allowing users to measure pH and temperature with only one electrode. Ideal for complex samples, such as biological media, foods and pharmaceuticals. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.

Supplier: PerkinElmer

Atd St Stl Tube W/Tenax Ta (PERKIN N9307005) 1 * 10 items

Supplier: Thermo Orion

This pH electrode is ideal for measuring micro volume samples. A PTFE protective sleeve over the glass stem provides greater durability than conventional micro pH electrodes and allows pH and temperature measurement of samples in 384 well plates or samples.
Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.

Supplier: ProSci Inc.

SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.

Supplier: Thermo Orion

This electrode with built-in temperature sensor is ideal for any application where the use of metallic reference electrodes would contaminate the samples. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.

Supplier: Thermo Orion

This combination pH electrode helps users to precisely conduct pH determinations. Its convenient flat surface tip measures pH in soft, moist surfaces both solid and semi-solid such as agar gel plates, meats, bread dough and similar samples. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.

Supplier: STERIS

STERAFFIRMVAPORIZED VH202 PROCESS INDICATOR 1 * 200 items

Supplier: ProSci Inc.

FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Variant 1 (isoform a) encodes the longest transcript. Variant 2 (isoform b) contains an alternate exon, which results in an early stop codon, compared to variant 1. Isoform b has a shorter C-terminus when compared to isoform a. Mutations in this gene are the most common cause of Fanconi anemia.

Supplier: Thermo Orion

This general purpose, semi-micro tipped combination electrode with top-performance glass body can be used for precise pH determinations in micro volume samples. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.

Supplier: Thermo Scientific

General Purpose Pro Centrifuges Cell Therapy Systems (CTS™) Series consist of equipment, documentation, and certifications, as well as compliance services that support Good Manufacturing Practice (GMP) requirements. The CTS Series helps you get up and running faster, stay compliant and current with all necessary regulatory certifications, navigate regulatory audits, and stay on schedule, taking cell therapy from discovery to clinical research and commercial manufacturing. The refrigerated 4 L (4×1000 ml) floor standing and bench models are designed to meet the needs of today’s rapid-fire discoveries, with updates to help get research done quickly, consistently, and reliably.

Supplier: Thermo Scientific

General Purpose Pro Centrifuges Cell Therapy Systems (CTS™) Series consist of equipment, documentation, and certifications, as well as compliance services that support Good Manufacturing Practice (GMP) requirements. The CTS Series helps you get up and running faster, stay compliant and current with all necessary regulatory certifications, navigate regulatory audits, and stay on schedule, taking cell therapy from discovery to clinical research and commercial manufacturing. The refrigerated 4 L (4×1000 ml) floor standing and bench models are designed to meet the needs of today’s rapid-fire discoveries, with updates to help get research done quickly, consistently, and reliably.

Supplier: ProSci Inc.

During vertebrate embryogenesis, a left-right axis is established. Secreted growth factors of the TGF-beta family, including gene products derived from nodal, lefty-1 and lefty-2, play crucial roles in establishing left-right asymmetries. TGF-beta (Transforming growth factor-beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells. TGF-beta actions are directed by ligand-induced activation of TGF-beta receptors. Complexes formed move into the nucleus, where they act as components of a transcriptional complex. Lefty, a novel member of the TGF-beta superfamily, inhibits TGF-beta signaling. Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF-beta receptor. Lefty also inhibits events downstream from R-Smad phosphorylation. Lefty provides a repressed state of TGF-beta-responsive genes. The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, and Lefty A and Lefty B in humans. Members of the TGF-beta superfamily require processing for their activation. Cleavage is therefore an essential step for Lefty activation. Lefty is synthesized as a large inactive precursor (42 kDa) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms). The 28 kDa form induces MAPK activity.

Supplier: HAMILTON BONADUZ

HC-75 H 9UM BULK RESIN 1 * 1 g

Supplier: ProSci Inc.

ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins. ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53. iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. This protein also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. iASPP is predominantly a cytoplasmic protein (isoform 1) but can also be found in the nucleus (isoform 2). iASPP is highly expressed in heart, placenta and prostate and is weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. The N-terminal region of isoform 1 is required for cytoplasmic localization. Defects in iASPP may be a cause of certain breast cancers and the protein is overexpressed in many patients suffering from breast carcinomas and expressing a wild-type p53/TP53 protein.

Supplier: ProSci Inc.

Since their discovery in the early 1990's, the peroxisome proliferator activated receptors (PPARs) have attracted significant attention. This is primarily because PPARs serve as receptors for two very important classes of drugs: the hypolipidemic fibrates and the insulin sensitizing thiazolidinediones. Peroxisome proliferators are non-genotoxic carcinogens that are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed PPARs. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Upon binding fatty acids or hypolipidemic drugs, PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate the expression of target genes. There are 3 known subtypes of PPARs: PPAR-alpha, PPAR-delta and PPAR-gamma. Mostly target genes are involved in the catabolism of fatty acids. Conversely, PPAR-gamma is activated by peroxisome proliferators such as prostaglandins, leukotrienes and anti-diabetic thiazolidinediones and affects the expression of genes involved in the storage of the fatty acids. PPAR-gamma may also be involved in adipocyte differentiation. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 through interaction with specific response elements.

Supplier: CUSTOM MADE CHEMICALS LAB

11 COMPONENTS MIX 1 * 500 mL

Supplier: Cytiva

Nucleon™ PhytoPure™ enables rapid chloroform extraction of high-quality, high molecular weight genomic DNA from plant and fungal samples with efficient removal of protein as well as polysaccharides.