Anti-C1orf110 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Bioss
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf110 gene product has been provisionally designated C1orf110 pending further characterization.
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Anti-C1orf177 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Supplier: Bioss
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf177 gene product has been provisionally designated C1orf177 pending further characterization. There are two isoforms of C1orf177 that are produced as a result of alternative splicing events.
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Anti-C1orf177 Rabbit Polyclonal Antibody (Cy3®)
Supplier: Bioss
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf177 gene product has been provisionally designated C1orf177 pending further characterization. There are two isoforms of C1orf177 that are produced as a result of alternative splicing events.
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Anti-C1orf177 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Supplier: Bioss
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf177 gene product has been provisionally designated C1orf177 pending further characterization. There are two isoforms of C1orf177 that are produced as a result of alternative splicing events.
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Anti-Radical Fringe Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Supplier: Bioss
Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila Fringe, a protein involved in development. Fringe proteins act upstream of the Notch Signalling pathway and are involved in boundary determination during segmentation. Each mammalian Fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical Fringe, also known as Beta-1,3-N-acetylglucosaminyltransferase Radical Fringe, is a 331 amino acid single-pass type II membrane protein that localizes to the membrane of the Golgi apparatus. Playing a key role in the development of the limb bud, Radical Fringe transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor. Lunatic Fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic Fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumourigenic in SCID mice.
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Anti-C1orf180 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Supplier: Bioss
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf180 gene product has been provisionally designated C1orf180 pending further characterization.
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Petri dishes, Star™ Dish
Supplier: PHOENIX BIOMEDICAL
Clear PS. Ideal for colony counting.
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Trousers, WX3
Supplier: Portwest
Portwest WX3 contemporary workwear is designed to the highest standards and offer a solution for everyday activity and working environments. Constructed with cutting edge fabrics giving superior abrasion resistance and exceptional all-day comfort. The WX3 work trousers are made from durable poly-cotton canvas fabric and includes triple stitched seams and stretch panelling providing excellent comfort and flexibility.
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Weld grind respirators starter kit with PX5 PAPR, Z4
Supplier: RPB SAFETY
The RPB Z4 w/ PX5 PAPR starter kit provides everything needed to perform industrial welding and grinding tasks with the utmost in safety but also now with unmatched comfort and further reduced cost in use.
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TSKgel® gel filtration columns, PW-type
Supplier: TOSOH BIOSCIENCE
These columns are designed for GFC of water soluble organic polymers, polysaccharides, oligosaccharides, DNA and RNA. They are based on a hydrophilic polymethacrylate matrix, which is stable from pH 2 to 12 and in aqueous eluents with up to 50% polar organic solvent.
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Anti-C11orf24 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Supplier: Bioss
C11orf24, also known as DM4E3, is a 449 amino acid single-pass type I membrane protein that is expressed in brain, lung, skeletal muscle, kidney, spleen, prostate, testis, ovary and small intestine, with highest expression in heart, placenta, liver, pancreas and colon, and low expression in thymus and leukocytes. C11orf24 is encoded by a gene located on human chromosome 11, which consists of approximately 135 million base pairs and 1400 genes. Chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumours, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
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Safety storage cabinets, type 90, Q-PEGASUS-90
Supplier: asecos
Fireproof safety cabinets, classified type 90 (fire resistant up to 90 minutes), safe, durable, robust and convenient with transport base and bicoloured cabinet design. The PEGASUS line is nearly identical to the CLASSIC line, but with integrated AGT (one handed operation for double door cabinets) and integrated TSA (door open arrest system and automatic door closing).
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Microplate readers, multi-mode, SpectraMax® M series
Supplier: MOLECULAR DEVICES
All SpectraMax® M series multi-mode microplate readers measure UV and visible absorbance, and fluorescence intensity measurements on microplates and cuvettes as standard. The SpectraMax® M2 and M2e readers provide two detection modes in one platform, and offer the the added functionality of bottom-read fluorescence for cell-based assays (M2e). The SpectraMax® M3, M4, M5 and M5e readers offer a modular, upgradeable dual monochromator microplate reader platform with a wide range of high performance multi-mode capabilities ideal for life science research and drug discovery screening.
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Autoclaves, Priorclave Compact
Supplier: Priorclave
Compact 40 benchtop and Compact 60 floor standing or benchtop autoclaves for the low volume user, with flexible operation usually only available in larger autoclave units. This flexibility is delivered by the TACTROL™ microprocessor control system, specially developed for laboratory autoclaves, with programming ranging from simple cycles to fully featured multi-program operation with logged records. All Priorclaves come complete with Biomaster antimicrobial coating, helping improved laboratory hygiene; it is effective against all bacteria and fungi including MRSA and therefore helps minimise the risk of cross contamination.
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High visibility overalls with bib and braces, 1015 PLU
Supplier: FRISTADS KANSAS
These overalls consist of different fabric combinations. The fluorescent material is water repellent and manufactured from 80% polyester and 20% cotton. The other parts are made of 65% polyester and 35% cotton with a soft nap on reverse. The reinforcement is made from 100 % polyamide.
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Immersion circulator, ICC series
Supplier: IKA
Compact ICC immersion circulators are ideal for tempering of liquids up to 150 °C. Suitable to use in open or covered bath vessels. The integrated pressure/ suction pump allows ICC units to be used for internal and external applications. Just connect the optional pump set. Both units can be used close to ambient temperatures when combined with optional cooling coil. Both models feature optical and acoustic safety warnings and adjustable safety circuit.
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Anti-FBXO21 Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
FBXO21 contains 1 F-box domain. It is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
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High visibility trousers, PW3, T501 Vision Hi-Vis
Supplier: Portwest
The thoughtfully designed, innovative hi-vis trousers are made from a 50+ UPF rated polyester/cotton fabric which blocks 98% of UV rays. Oxford fabric reinforcement at key abrasion points and triple stitching throughout guarantees maximum durability.
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Heating circulators
Supplier: HUBER
The low bath volume means these circulators are ideal for controlling the temperature of small external applications, or for direct temperature control of small objects directly in the bath. The Pilot ONE® controller offers a brilliant 14,5 cm touch screen with graphic functions and a comfortable navigation menu in 11 languages plus USB and Ethernet connections.
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Amersham™ Protran® Western Blotting Membranes, Nitrocellulose
Supplier: Cytiva
Amersham™ Protran® membranes are manufactured from 100% pure nitrocellulose to ensure the highest binding capacity possible. They are compatible with a variety of detection methods, including isotopic, chemiluminescent, colorimetric and fluorescent. No methanol pre-wetting step is required, making this the membrane of choice for proteins which prefer aqueous environments. Prior to transfer the membrane is simply wetted with water, and then placed in the transfer buffer. No other pretreatment steps are necessary.
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Holster trousers, WX3
Supplier: Portwest
Portwest WX3 contemporary workwear is designed to the highest standards and offer a solution for everyday activity and working environments. Constructed with cutting edge fabrics giving superior abrasion resistance and exceptional all-day comfort. The WX3 holster trousers are made from durable poly-cotton canvas fabric and includes triple stitched seams and stretch panelling providing excellent comfort and flexibility.
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Trousers, Crafts, NYC-2018, Cordura®
Supplier: FRISTADS KANSAS
Craftsman trousers in strong and light weight ripstop material, with ventilation panels at back and behind knees for increased comfort when working in warm environments.
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Pipette tips, Standard
Supplier: Brand
These tips are manufactured under cleanroom conditions and are automatically packaged to ensure that the tips are consistently free from contamination.
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Anti-ATP6V0B Rabbit Polyclonal Antibody
Supplier: ProSci Inc.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.
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DNA ladders, GeneRuler™ and O'GeneRuler™
Supplier: Thermo Fisher Scientific
Thermo Scientific™ GeneRuler™ and O'GeneRuler™ DNA ladders are mixtures of chromatography-purified individual DNA fragments. The GeneRuler™ line includes the most popular ladders, such as the 100 bp and 1 kb DNA Ladder. GeneRuler™ DNA ladders are available in two formats: Conventional (provided in TE buffer) and a ready-to-use format (premixed with 6X DNA Loading Dye which contains bromophenol blue and xylene cyanol FF). O'GeneRuler™ DNA ladders are another ready-to-use version of GeneRuler™ DNA ladders that are premixed with 6X Orange DNA Loading Dye.
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High purity qualitative filter paper
Supplier: Ahlstrom-Munksjö
These qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers cover a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.
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Ultra-low temperature refrigerated circulators
Supplier: JULABO GmbH
Ultra-low temperature refrigerated circulators for heating and cooling. The units are suitable for external temperature applications with simultaneous operation in the bath tank. The units provide particularly high heating and cooling capacities for rapid heating and cooling times even for large volume, external systems. FP models offer proportional cooling control to ensure energy saving performance and to reduce heat generation to the environment. Models with the designation W are water cooled. All models have handles and castors which allow easy transportation and drain ports for conveniently draining the bath fluid. The units offer an improved insulation to prevent ice formation and have a filling level display. Typical applications: Temperature control of jacketed reaction vessels, autoclaves, mini plant installations, kilo labs, freezing point determination, calibration at low temperatures and petroleum testing.
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Thermal imager, testo 865s
Supplier: Testo
The testo 865s thermal imager offers professional technology and concentrates on functions which are needed in a contractor's daily work. The user-friendly thermal imager, optimized for fast and efficient work. With the testo ScaleAssist functions ensuring optimum setting of the thermal image scale for building thermography and the IFOV warner making sure to avoid measurement errors, always generate the perfect infrared image. This combines all the important properties required for high-quality thermographic measurement – it is accurate, robust, fast and reliable. The case supplied with the thermal imager means it can be conveniently transported, so it is always there for you when needed.
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TSX™ Core Ultra-Low Temperature Freezers, −86 °C
Supplier: Thermo Scientific
TSX™ core series is engineered for reliability and designed for everyday use. When choosing a ULT freezer, protecting your valuable samples is the top priority. The Thermo Scientific™ TSX™ core series ULT freezers are designed with this in mind, offering reliable sample protection even in the busiest laboratory environments.