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Affinity chromatography media, high capacity endotoxin removal resin, Pierce™

Affinity chromatography media, high capacity endotoxin removal resin, Pierce™

Supplier: Thermo Fisher Scientific

Pierce™ High Capacity Endotoxin Removal Resins are ideal for the removal of endotoxins from protein or antibody samples prior to cell transfection or animal injection.

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LR white acrylic resins, Sigma-Aldrich®

Supplier: SIGMA ALDRICH MICROSCOPY

Benzoyl peroxide (B5907) is specifically formulated as an initiator for these resins.

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NF-κB Activation Inhibitor III ≥99%

Supplier: Cayman Chemical

NF-κB Activation Inhibitor III ≥99%

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Calpain inhibitor II ≥95%

Supplier: Thermo Fisher Scientific

An inhibitor of calpains I and II.

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BML-277 Chk2 inhibitor ≥98% (by TLC)

Supplier: Enzo Life Sciences

BML-277 is a highly selective inhibitor of Chk2 (IC50=15nM). It displays potent radioprotective activity and prevents apoptosis of human T cells subjected to ionizing radiation (EC50= 3-7.6µM). Useful tool for dissecting the role of Chk2 in cellular signaling.

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Bisphenol A diglycidyl ether resin

Supplier: Thermo Fisher Scientific

Bisphenol A diglycidyl ether is used to inhibit the peroxisome proliferator-activated receptor (PPARγ) and adipocyte differentiation and it induce apoptosis in tumor cells.

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Sulfhydryl coupling resin for antibody purification

Sulfhydryl coupling resin for antibody purification

Supplier: G-Biosciences

This sulphhydryl coupling resin is designed for coupling of peptides and proteins to a solid 6% agarose support through free sulfhydryl groups (-SH). The iodoacetyl groups of the sulfhydryl coupling resin specifically react with free sulfhydryls to form covalent, permanent thioether bonds.

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GSK-3 inhibitor IX, InSolution™, Millipore®

Supplier: Merck Millipore (Calbiochem‎)

InSolution™ GSK-3 Inhibitor IX controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.

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Sphingosine kinase inhibitor ≥98%, Millipore®

Supplier: Merck Millipore (Calbiochem‎)

The sphingosine kinase inhibitor controls the biological activity of sphingosine kinase. This small molecule/inhibitor is primarily used for cell signaling applications.

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Trityl chloride resin 0,5 - 2,5 mmol/g on poly(styrene-divinylbenzene), cross-linked with 1% DVB 100-200 mesh

Supplier: Thermo Fisher Scientific

Trityl chloride resin 0,5 - 2,5 mmol/g on poly(styrene-divinylbenzene), cross-linked with 1% DVB 100-200 mesh

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Affinity chromatography resin, chelating nickel

Affinity chromatography resin, chelating nickel

Supplier: G-Biosciences

Nickel chelating resin is an immobilised metal affinity chromatography (IMAC) resin that was specifically designed to utilise Ni²⁺ for the purification of nickel binding proteins, including 6x histidine tagged proteins.

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Affinity purification Streptavidin Resin and buffers

Supplier: G-Biosciences

Streptavidin Resin is designed for the single step small and large scale affinity purification of proteins and antibodies with a biotin tag. Biotin, a 244 Da vitamin (Vitamin H) molecule, exhibits an extraordinary binding affinity for avidin (Ka=10¹⁵ M⁻¹) and streptavidin (Ka=10¹⁵ M⁻¹). Biotin and (strept)avidin interaction is rapid and once the bond is established it can survive up to 3M guanidinehydrochloride and extremes of pH. Biotin-avidin bonds can only be reversed by denaturing the avidin protein molecule with 8M guanidine-hydrochloride at pH 1,5 or by autoclaving. The biotinylated molecules are efficiently probed with avidin or streptavidin conjugated to reporter molecules, such as peroxidases or phosphatases.

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Ion exchange resins, beads, BAKER ANALYZED® IONAC® NM-60 H+/OHˉ Form, Type I 16-50 Mesh (mixed bed exchanger), J.T.Baker®

Ion exchange resins, beads, BAKER ANALYZED® IONAC® NM-60 H+/OHˉ Form, Type I 16-50 Mesh (mixed bed exchanger), J.T.Baker®

Supplier: Avantor

Ion exchange resins, beads, BAKER ANALYZED® IONAC® NM-60 H+/OHˉ Form, Type I 16-50 Mesh (mixed bed exchanger), J.T.Baker®

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STAT3 Inhibitor V, Stattic ≥98% (by TLC)

Supplier: Enzo Life Sciences

Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways. It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production. In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation.

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Affinity purification resins, anti-His, GenScript®

Supplier: Genscript

Anti-His affinity resins are designed for purification of His-tagged protein. Composed of agarose and conjugated THE™ anti-His monoclonal antibody, they are compatible with most commonly used reagents at certain concentrations.

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GSK-3β inhibitor VIII

Supplier: Thermo Fisher Scientific

A cell-permeable, potent, and selective inhibitor of GSK-3beta.

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J.T.Baker® BAKERBOND® PROchievA™, Affinity Chromatography Resin, Recombinant Protein A

J.T.Baker® BAKERBOND® PROchievA™, Affinity Chromatography Resin, Recombinant Protein A

Supplier: Avantor

The J.T.Baker® BAKERBOND® PROchievA™ protein A resin offers superior dynamic binding capacity with excellent alkaline stability linked to Avantor's proprietary ligand.

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IgG purification resin, Pearl™

Supplier: G-Biosciences

The Pearl™ IgG purification resin allows for the one-step purification of immunoglobulin G from serum. The resin binds the high abundant, non-IgG proteins (i.e. albumin) and allows the IgG molecules to pass through in a physiological buffer. The IgG molecules can be stored or used in downstream applications without further clean-up, such as ammonium sulphate precipitation.

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DuPont™ AmberLite™ IRN77 H cation exchange resin

DuPont™ AmberLite™ IRN77 H cation exchange resin

Supplier: VWR Chemicals

DuPont™ AmberLite™ IRN77 H Ion Exchange Resin Nuclear-grade, Uniform Particle Size, Gel, Strong Acid Cation Exchange Resin for Water Treatment Applications in the Nuclear Power Industry.

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Recombinant protein purification resins, IMAC

Recombinant protein purification resins, IMAC

Supplier: G-Biosciences

Cobalt chelating resin, for the purification of 6X His proteins

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CL-82198 (MMP-13 inhibitor) ≥98% (by TLC)

Supplier: Enzo Life Sciences

A novel and selective inhibitor of MMP-13 (89% at 33 µM). Acts via binding to the S1' pocket of MMP-13 without metal chelation.

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PDGF receptor tyrosine kinase inhibitor IV ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Cell-permeable PDGFR inhibitor with antiproliferative properties.

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Amberlite® IRN-78, Ion exchange resin cationic type (OH-) ion-exchange resin

Amberlite® IRN-78, Ion exchange resin cationic type (OH-) ion-exchange resin

Supplier: Thermo Fisher Scientific

Amberlite® IRN-78, Ion exchange resin cationic type (OH-) ion-exchange resin

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Coupling resin, CarboxyLink™

Coupling resin, CarboxyLink™

Supplier: Thermo Fisher Scientific

CarboxyLink™ coupling resin is used for covalent immobilisation of peptides or other carboxyl-containing molecules to a porous, beaded resin for use in affinity purification procedures.

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Affinity purification resins, UltraLink™ iodoacetyl resin

Affinity purification resins, UltraLink™ iodoacetyl resin

Supplier: Thermo Fisher Scientific

UltraLink™ iodoacetyl resin is a durable, porous resin that is activated to enable efficient and direct covalent immoblisation of peptides and other ligands through their sulfhydryl groups (-SH) for use in affinity purification procedures.

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ReadiPrep™ Protein G-Agarose Resin

ReadiPrep™ Protein G-Agarose Resin

Supplier: AAT Bioquest

ReadiPrep™ Protein G-Agarose Resin is a high-quality affinity resin designed for the isolation and purification of immunoglobulin classes, subclasses, and fragments from mammalian serum and biological fluids.

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Pierce™ Detergent Removal Spin Columns and Resin

Pierce™ Detergent Removal Spin Columns and Resin

Supplier: Thermo Fisher Scientific

Pierce™ Detergent removal resin enables removal of commonly used ionic, non-ionic and zwitterionic detergents from protein/peptide digest solutions.

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Hydrazide resin, UltraLink™

Hydrazide resin, UltraLink™

Supplier: Thermo Fisher Scientific

UltraLink™ Hydrazide resin is used to prepare affinity columns with antibodies or other glycolsylated proteins.

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MMP-9/MMP-13 inhibitor I ≥95% (by HPLC), Millipore®

Supplier: Merck Millipore (Calbiochem‎)

A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC₅₀=900 pM) and MMP-13 (IC₅₀=900 pM).

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Control agarose resin, Pierce™

Control agarose resin, Pierce™

Supplier: Thermo Fisher Scientific

Pierce™ Control Agarose Resin is underivatised beaded agarose support for pre-clearing protein immunoprecipitation samples.

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