8311 Results for: "FISCHER+LABORTECHNIK&pageNo=36&view=easy"

Supplier: Bioss

FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation.

Supplier: Bioss

C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.

Supplier: Bioss

C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.

Supplier: Bioss

FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation.

Supplier: Avantor Fluid Handling

Achieve high accuracy and low pressure drop!

Supplier: Bioss

C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.

Supplier: Spectrum Laboratories

Hollow fibre filter modules are particularly useful in tangential flow filtration because processes can easily be scaled-up from small volume applications to full-scale production.

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö manufactures a series of extremely high purity, acid washed filter papers designed for use in analytical and gravimetric analysis. The quantitative grades are manufactured from top quality cotton linters using ultra-pure, deionised water and are further treated with dilute acid to remove any remaining organic and inorganic impurities. All quantitative grades are manufactured in a strictly controlled environment that ensures high uniformity and high purity from filter to filter.

Supplier: Thermo Fisher Scientific

Natural tubes are made from 100% virgin PP to help ensure maximum clarity for biological-based work.

Supplier: Thermo Fisher Scientific

Superior comfort, performance, reliability and easiness of maintenance in one of the lightest pipettes available in the market.

Supplier: FRISTADS KANSAS

Vest made from 65% polyester and 35% cotton; napped inner.

Supplier: Bioss

Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialised signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.

Supplier: Bioss

Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialised signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.

Supplier: KINEMATICA

Stand model, volume range 0,1 to 10000 ml. Benchtop homogeniser with powerful motor and space-saving slimline design, which is easy to handle. Ideal for any dispersing and homogenising task. Interchangeable drive extensions mean different types of stand can be used.

Supplier: Bioss

CCDC36 , also known as CT74 (cancer/testis antigen 74), is a 584 amino acid protein that contains coiled-coil domains and is expressed as three alternatively spliced isoforms. The gene encoding CCDC36 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Supplier: Shenandoah Biotechnology

GM-CSF is a hematopoietic growth factor with the ability to form colonies of granulocytes and macrophages. Enhances the number of circulating white blood cells and function of neutrophils and monocytes. Regulates multiple functions via transcription factors in the differentiated cells, including cell survival, proliferation, and maturation. Generates in vitro murine and human DC populations from bone marrow precursors and blood monocytes, respectively.

Supplier: Shenandoah Biotechnology

IL-3 is a species-specific cytokine and pleiotropic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil, and mast cell lineages.

Supplier: Bioss

C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.

Supplier: Bioss

C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.

Supplier: VWR Collection

Routine inverted fluorescence microscopes for transmitted brightfield, darkfield, phase contrast and fluorescence observations. Ideal for tissue culture research in clinical and biotechnology laboratories.

Supplier: Thermo Orion

Use the Orion Star T930 ion titrator for dedicated ion titrations including salt in foods, chloride in drinking and wastewater, ammonia and Total Kjeldahl Nitrogen (TKN) of wastewater, surfactants in consumer products and total hardness of water.

Supplier: Kango

Ergonomic and auto-adaptive chairs or stools made from soft PU or wood.
Nobody has perfect symmetrical morphology. This is why people have back problems, sometimes with a feeling of heavy legs. The answer to this problem can be found in the main features of the Koncept chairs and stools.

Supplier: MACHEREY-NAGEL

NUCLEODUR® C18 PolarTec is an octadecyl modified silica phase with embedded polar group for HPLC.

Supplier: MERKLINGER PRAZISION WERKZEUG

This column-packing technology is based on a combination of vacuum suction with subsequent column bed compression that stabilises the packing. A common water-jet pump is used to generate the vacuum. The sorbent slurry is sucked through a packing reservoir into the column by applying low pressure at the bottom end of the column.

Supplier: VWR Collection

Agilent OpenLab CDS is the next generation chromatography data system, designed for ease of use and productivity. OpenLab CDS offers the most comprehensive instrument control and data acquisition for Hitachi HPLC and amino acid analysers. In addition, it supports an expanded array of instrumentation from other vendors, for example Agilent LC, GC and LC/MS. Whether you like to control a single instrument or a huge network of different analytical instruments, OpenLab CDS grows with your needs.

Supplier: VISION ENGINEERING

High productivity eyepiece-less stereo microscope.

Supplier: OHAUS

This digital waving shaker provides precise speed control and a smooth, low foaming, three dimensional, 'wave' motion. Ideal for use in a wide range of laboratory applications and designed to be used in a variety of environmental conditions. Tray includes a non-skid rubber mat that is suitable for holding Petri dishes.

Supplier: Orflo

The Moxi™ Z automated cell counter combines the the 'gold-standard' Coulter Principle typically used in high-end instruments with a patented thin-film sensor technology to provide highly accurate and repeatable direct cell/particle size and count over a broad dynamic range (2 to 34 µm), with single cell resolution.

Supplier: LABCONCO

This HEPA-filtered glove box has inlet and outlet HEPA filters and provides a leak-tight physical barrier to protect the operator from hazardous airborne particulates and powders.

Supplier: GENLAB

A range of efficient, reliable, cost effective incubators ideal for biological analysis, research and general laboratory applications. The INC has a horizontal style with the controls fitted to one side of the door. All the models listed below feature an exterior of sheet steel, finished in an easy clean powder coated paint and a stainless steel inner chamber. Units are heated by means of Incoloy sheathed elements; positioned below the chamber floor for natural convection units and fitted around the fan on the back or side wall of the chamber for fan assisted units (200 L only).