94231 Results for: "Europium+(II)+bromide&pageNo=9"

A potent and selective, cell-permeable inhibitor of nitric oxide (NO)-sensitive soluble guanylyl cyclase (sGC). Inhibition is irreversible. Inhibits also the basal, the YC-1 and the coenhanced sGC activity. Complete inhibition of NO-induced relaxation in vascular and nonvascular smooth muscle at 1μM.

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Chlorpromazine hydrochloride ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Antipsychotic working on a variety of receptors in the CNS

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NPC-15437 dihydrochloride ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

PKC inhibitor

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Tyrphostin AG 527 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Tyrphostin AG 527 ≥98% (by HPLC)

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4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Potent inhibitor of histone deacetylases (HDACs) (IC50≤1µM).

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Daphnetin ≥97%

Supplier: ENZO LIFE SCIENCES

Protein kinase inhibitor

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Curcumin (from Curcuma longa) ≥98% (by HPLC), high purity

Supplier: ENZO LIFE SCIENCES

Curcumin (from Curcuma longa) ≥98% (by HPLC), high purity

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Catharanthine tartrate (from Catharanthus roseus) ≥90% (dry basis)

Supplier: ENZO LIFE SCIENCES

Starting material for the synthesis of the antitumor drugs vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.

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D-myo-Inositol-1,4,5-trisphosphate, hexapotassium salt ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Product of phosphatidylinositol phospholipid hydrolysis.

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Salubrinal ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Salubrinal ≥98% (by HPLC)

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SANT-2 ≥95%

Supplier: ENZO LIFE SCIENCES

Smoothened inhibitor

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Rockout ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

A cell permeable, selective, and ATP-competitive inhibitor of Rho kinase (ROCK) activity (IC50=25µM). Does not inhibit the activation of Rho nor does it affect the in vitro activities of MLCK, PKCα, and SAPK2a/p38α. Shown to be less potent than Y-27632.

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MS-275 ≥95% (by 1H-NMR)

Supplier: ENZO LIFE SCIENCES

HDAC1 inhibitor

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1-Azakenpaullone ≥95% (by NMR)

Supplier: ENZO LIFE SCIENCES

GSK-3beta inhibitor

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SU 9516 ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Cell permeable, potent, selective and ATP-competitive inhibitor of CDK2/cyclin A (IC50=22nM), CDK1/cyclin B (IC50=40nM) and CDK4/cyclin D1 (IC50=200nM). Has no effect on the activity of PKC, p38, PDGFRβ and EGFR (IC50>10µM). Displays anti-proliferative and pro-apoptotic properties in tumor cells. Inhibits proliferation of growth factor-stimulated colon carcinoma cells by binding to CDK2 and thus preventing the phosphorylation of pRb and its dissociation from E2F.

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CDK1/2 Inhibitor III ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Cell permeable triazolo-diamine compound that displays anti-proliferative properties in various human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).

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6,7-Dihydro-5H-cyclopenta[b]pyridin-7-amine hydrochloride 97+%

Supplier: Apollo Scientific

6,7-Dihydro-5H-cyclopenta[b]pyridin-7-amine hydrochloride 97+%

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(+)-1-Deoxynojirimycin 99% min

Supplier: Apollo Scientific

(+)-1-Deoxynojirimycin 99% min

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1-Bromo-4-butoxybenzene 97%

Supplier: Apollo Scientific

1-Bromo-4-butoxybenzene 97%

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Benzylammonium chloride 99%

Supplier: Apollo Scientific

Benzylammonium chloride 99%

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Ethyl-2-chloronicotinate 98%

Supplier: Apollo Scientific

Ethyl-2-chloronicotinate 98%

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NG-Hydroxy-L-arginine monoacetate ≥98%

Supplier: ENZO LIFE SCIENCES

Intermediate in NO biosynthesis

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N-ω-Hydroxy-L-norarginine acetate salt ≥97% (by TLC)

Supplier: ENZO LIFE SCIENCES

Potent and reversible arginase inhibitor. Specifically interacts with the manganese-cluster of the arginase active site. Does not act as a substrate or as an inhibitor of NOS.