A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS

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N,N-Dimethylsphingosine, D-erythro ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Sphingosine kinase inhibitor

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Mifepristone ≥99%

Supplier: ENZO LIFE SCIENCES

Progesterone receptor ligand.

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1-(3-Methylpyridin-2-yl)-1,4-diazepane 95%

Supplier: Thermo Fisher Scientific

1-(3-Methylpyridin-2-yl)-1,4-diazepane 95%

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Ampicillin sodium salt ≥93%

Supplier: ENZO LIFE SCIENCES

β-Lactam antibiotic. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking). Inactivates transpeptidases on the inner surface of the bacterial cell membrane. Effective against Gram-negative and Gram-positive bacteria.

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Farnesyl thiotriazole ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

PKC activator.

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RK-682 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

RK-682 is a novel tyrosine phosphatase inhibitor isolated from Streptomyces sp. It inhibits the dual specificity VHR phosphatase (IC50=2.0µM) selectively over CD45 (IC50=54µM), Cdc25B and PTP1B (IC50~42µM). RK-682 inhibits cell cycle progression of Ball-1 cells at the G1/S transition and enhances ATP-induced long-term potentiation in guinea pig hippocampal CA1 neurons. Shows potent activity against HIV-1 protease.

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L(-)-Galactose ≥98%

Supplier: Thermo Fisher Scientific

L(-)-Galactose ≥98%

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1,2-Diphenylcyclopropane cis- and trans-mixture 97%

Supplier: Thermo Fisher Scientific

1,2-Diphenylcyclopropane cis- and trans-mixture 97%

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3-Aminocrotononitrile mixture E/Z 96%

Supplier: Thermo Fisher Scientific

3-Aminocrotononitrile mixture E/Z 96%

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11-Bromo-1-undecene ≥96%

Supplier: Thermo Fisher Scientific

11-Bromo-1-undecene ≥96%

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1-Chloro-2-nitrobenzene ≥99%

Supplier: Thermo Fisher Scientific

1-Chloro-2-nitrobenzene ≥99%

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3-Methylbenzophenone ≥99%

Supplier: Thermo Fisher Scientific

3-Methylbenzophenone ≥99%

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Apicidin ≥99% (by HPLC, TLC)

Supplier: ENZO LIFE SCIENCES

HDAC inhibitor

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N-Benzoylsuccinimide 97%

Supplier: Thermo Fisher Scientific

N-Benzoylsuccinimide 97%

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Hexaamminecobalt trichloride ≥97%

Supplier: Thermo Fisher Scientific

Hexaamminecobalt trichloride ≥97%

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2-Chloroethyldiisopropylammonium chloride 98%

Supplier: Thermo Fisher Scientific

2-Chloroethyldiisopropylammonium chloride 98%

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2,2'-Ethylenebis(1,3-dithiane) ≥98%

Supplier: Thermo Fisher Scientific

2,2'-Ethylenebis(1,3-dithiane) ≥98%

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Calyculin A ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Inhibitor of PP1 and PP2A

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2-Ethylamino-3-methoxypyridine 99%

Supplier: Thermo Fisher Scientific

2-Ethylamino-3-methoxypyridine 99%

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BML-277 Chk2 inhibitor ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

BML-277 is a highly selective inhibitor of Chk2 (IC50=15nM). It displays potent radioprotective activity and prevents apoptosis of human T cells subjected to ionizing radiation (EC50= 3-7.6µM). Useful tool for dissecting the role of Chk2 in cellular signaling.