48197 Results for: "Di-4-ANEPPS&pageNo=8"

Temperature restriction (for UN/UF/UNplus/UFplus and models UF TS) Temperatures: +60, +70, +80, +95, +100, +120, +160, +180, +200, + 220 or +250 C (Please, indicate upon ordering) 1 * 1 items

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Zinc nitrate hexahydrate, 98% 1 * 2.500 g

Supplier: Thermo Fisher Scientific

Zinc nitrate hexahydrate, 98% 1 * 2.500 g

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2-Methyl-3-buten-1-ol 98%

Supplier: Thermo Fisher Scientific

Appearance: Clear colorless Liquid

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Pyridoxamine dihydrochloride 98%

Supplier: Thermo Fisher Scientific

Pyridoxamine dihydrochloride 98%

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4-(Trifluoromethyl)benzenesulphonyl chloride 98%

Supplier: Thermo Fisher Scientific

4-(Trifluoromethyl)benzenesulphonyl chloride 98%

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5-Cyano-2-thiopheneboronic acid 98%

Supplier: Thermo Fisher Scientific

5-Cyano-2-thiopheneboronic acid 98%

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Estradiol 98%

Supplier: Thermo Fisher Scientific

Estradiol 98%

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Ethanol CHROMASOLV™, for HPLC, absolute, ≥99.8% 1 * 18 L

Supplier: Honeywell Chemicals

Ethanol CHROMASOLV™, for HPLC, absolute, ≥99.8% 1 * 18 L

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Anti-HIF1A Mouse Monoclonal Antibody (Purified, BSA-free) [clone: HIF1A-84]

Supplier: Biotium

HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc.) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains stable under both conditions. Besides their critical role in hypoxic response, HIF1s regulates the transcription of genes responsible for angiogenesis, erythropoiesis/iron-metabolism, glucose metabolism, cell proliferation/survival, adipogenesis, carotid body formation, B lymphocyte development and immune reactions.

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lOVIBOND 28 89 412 - Chlorine, pH, liquid reagents 0.02 - 4 mg/l Cl2 / 6.5 - 8.4 pH 1 * 1 items

Supplier: Lovibond

lOVIBOND 28 89 412 - Chlorine, pH, liquid reagents 0.02 - 4 mg/l Cl2 / 6.5 - 8.4 pH 1 * 1 items

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Wipe rolls, Multitex® Premium extra z 80

Supplier: Zellstoff-Vertriebs-GmbH & Co. KG

These high-quality non woven wipes are suitable for moist and dry cleaning applications.

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Mobile printer

Supplier: Testo

Designed to create immediate proof of measurement data and can be used to carry out simple and quick checks while transporting climate sensitive goods.