97589 Results for: "Desiccator+Lids&pageNo=25&view=easy"

Supplier: ProSci Inc.

Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. Complex formation between IL-21R and the common gamma chain (gammac) is required for signalling. IL-21R is expressed mainly on B cells (highest on mature, activated, follicular and germinal center B cells), NK cells and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells and keratinocytes. B cell IL-21R engagement induces Blimp1 (which mediates plasma cell differentiation) and is important for memory responses. IL-21R engagement on mouse NK cells enhances their cytotoxic activity and IFN-gamma production. IL-21R engagement on CD8+ T cells aids control of viral infection and tumour growth; IL-21R is also necessary for sufficient numbers of regulatory T cells to combat chronic inflammation. IL-21R expression is often upregulated in allergic skin inflammation, systemic lupus erythematosus and diffuse large B cell lymphoma (DLBCL).

Supplier: Cytiva

Ni Sepharose™ excel is an IMAC medium pre-charged with nickel ions very strongly bound to a chelating ligand. Samples that usually cause stripping of metal ions can, therefore, be loaded to the medium. Ni Sepharose™ excel is designed primarily for capture and purification of histidine-tagged proteins secreted into cell culture supernatants from eukaryotic cells such as insect cells or CHO cells.

Supplier: Ahlstrom-Munksjö

These qualitative grades of filter paper are recommended for use in analytical methods which determine or identify particulate constituents of a mixture irrespective of the amount present. Qualitative filter papers are often used in routine separation work that still requires high purity and consistent performance. These filter papers cover a wide range of laboratory applications, as liquids clarification, qualitative analytical separations for precipitates and buffers filtration, and are also used for soil analysis and in food and beverage testing. Wet-strengthened grades contain a reinforcement agent that increases their resistance to rupture when wet, such as in vacuum filtration, and their resistance when filtering acidic solutions.

Supplier: PHC Corporation

These cooled incubators are designed to meet a variety of advanced experimental needs, ranging from microorganism cultures and plant germination tests to various constant temperature experiments. Design includes a window made from triple layer glass (which can be shaded), lighting in the chamber (15 Watt), cable pass through as standard. MIR-154/MIR-254 only: Control panel with LCD display. DC fan to protect medium from drying out. Reversible door for left or right-hand door opening. Remote monitoring with DAQ (data acquisition) software. MIR-554: Auto diagnostic function, programmable with up to three steps, 1 to 99 cycles or endless. Programme memory backup for ±5 hours.

Supplier: VARIAN

POLYMERIC FEP TUBING 1/8INCH X 0.062INCH 1 * 1 items

Supplier: PFEIFFER VACUUM

HISCROLL 6 STANDARD 1 * 1 items

Supplier: CUSTOM MADE CHEMICALS LAB

Potassium Permanganate 0.2M (1N). Duree de conservation : 24 mois. Store under normal laboratory conditions, at temperatures between 15 to 25C 1 * 1 kg

Supplier: DWK Life Sciences

VIAL CRIMP TOP CLEAR 65/30 MM 1 * 100 items

Supplier: C LECTA

DENARASE® is a highly active endonuclease from Serratia marcescens. This enzyme is used in biopharmaceutical manufacturing to eliminate plasmid and host cell DNA/RNA. DENARASE® is manufactured under GMP conditions and is widely applied during the purification of viral vectors for gene/cell therapies and vaccines.

Supplier: HONEYWELL SAFETY

GLOVE DEEP BLUE WINTER GAUGE 13 S.8 1 * 1 PAIR

Supplier: BEHR

Determination of biodegradability: laboratory water treatment system in borosilicate glass 3.3, complete apparatus 1 * 1 items

Supplier: witeg Labortechnik

Flask for collecting nitrogen 25ml, with cylindrical stopcock,120x32mm, st14/23,acc. to schlenk, null

Supplier: CAPITAL SAFETY

DBI-SALA Quick Wrap Tape II, Blue , 2,74m 1 * 10 items

Supplier: HUBER

Recirculating Cooler with Pilot ONE temperature controller -10...40 C 1 * 1 items

Supplier: Kautex

SCREW CAP PE RED WITH PULL-OFF 60MM 1 * 1.000 items

Supplier: CUSTOM MADE CHEMICALS LAB

1 component: PBB 77 [CAS:77102-82-0] 35mg/l in Iso-octane CRM, ISO 17034 and ISO 17025 Conservation 12 months. Store under normal laboratory conditions, at temperatures between 15C to 25C 1 * 1 mL

Supplier: CUSTOM MADE CHEMICALS LAB

1 component: PBB 101 [CAS:67888-96-4] 35mg/l in Iso-octane CRM, ISO 17034 and ISO 17025 Conservation 12 months. Store under normal laboratory conditions, at temperatures between 15C to 25C 1 * 1 mL

Supplier: HONEYWELL SAFETY

GLOVE DEEP BLUE WINTER GAUGE 13 S.10 1 * 1 PAIR

Supplier: witeg Labortechnik

Tubing threaded 22x110x1.8mm gl25 with screw threaded, straight,acc. to din 12216, with iso screw thread,made of borosilicate glass , available with screw thread gl, rd or svl null

Supplier: Merck

EHEC is capable of inducing life threatening illnesses, particularly in people with immune deficiency, young children and the elderly. Although the most common cause of EHEC is E. coli O157, other serotypes, such as O26, O45, O103, O111, O121 and O145, are also relatively frequent causes of infection. Typical symptoms are severe abdominal pain and diarrhoea, which is initially watery but often becomes bloody. E. coli are gram-negative, non sporulating, facultative anaerobic bacilli. Amongst the pathogenic E. coli, Verotoxin-forming strains (STEC or VTEC) have gained importance in recent years. The group of enterohaemorrhagic E. coli (EHEC) with its highly pathogenic serovar O157:H7 strain is particularly interesting in this respect. The main sources of infection are contaminated, raw or insufficiently heated foods of animal origin, such as meat and dairy products. The reservoir for EHEC is the gut of ruminants. Microorganisms can enter food during the processing of meat and dairy products if hygienic conditions are inadequate. The drastic increase in the incidence of food contamination caused by E. coli O157 demands reliable and rapid methods of detection. Innovative, rapid tests make screening for pathogenic organisms easier. Complete test sets for the detection of pathogens and toxins. The one-step format reduces the possibility of errors during handling. In addition to tests for the most common cause of infection, E. coli O157, there exits a 24-H screening protocol for VTEC, including E. coli O104:H4, based on Rapidcult™ E. coli enrichment combined with detection using Duopath® Verotoxins.

Supplier: Biotium

Phalloidin is a toxin isolated from the deadly Amanita phalloides mushroom. It is a bicyclic peptide that binds specifically to F-actin. Fluorescent conjugates of phalloidin are convenient tools to investigate the distribution of F-actin in fixed and permeabilised cells or tissue sections. One unit (U) of phallodin is sufficient to stain one sample (200 µl staining volume). A highly selective actin filament stain for fixed and permeabilised cells. Labeled phalloidins have similar affinity for both large and small filaments.

Supplier: OMEGA BIO-TEK

Plasmid isolated with traditional purification procedures normally contain high levels of endotoxins that can significantly interfere with transfection experiments downstream. The E.Z.N.A.® Endo-Free Plasmid kits integrate an efficient endotoxin removal step into the plasmid purification procedure to produce high quality transfection grade plasmid.

Supplier: Bioss

Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognise the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognises one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognises the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognises the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognise the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Supplier: Bioss

FBXO25 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif, the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains, Fbls containing leucine rich repeats, and Fbxs containing either different protein protein interaction modules or no recognizable motifs. FBXO25 belongs to the Fbxs class. There are three named isoforms produced by alternative splicing.FBXO25, also known as FBX25, is a 367 amino acid protein that contains one C-terminal F-box domain and belongs to the Fbx class of the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Expressed at high levels in brain, FBXO25 localizes predominantly to the nucleus and directly interacts with Skp1 p19 and CUL-1. Disruption of the gene encoding FBXO25 can lead to X-linked mental retardation.

Supplier: ProSci Inc.

Neutrophil gelatinase-associated lipocalin(LCN2) is a secreted protein and belongs to the calycin superfamily. This protein is released from injured tubular cells after various damaging stimuli, is already known by nephrologists as one of the most promising biomarkers of incoming Acute Kidney Injury (AKI). Recent evidence also suggests its role as a biomarker in a variety of other renal and non-renal conditions. Moreover, recent studies seem to suggest a potential involvement of this factor also in the genesis and progression of chronic kidney diseases. NGAL is the first known mammalian protein which specifically binds organic molecules called siderophores, which are high-affinity iron chelators. NGAL, first known as an antibacterial factor of natural immunity, and an acute phase protein, is currently one of the most interesting and enigmatic proteins involved in the process of tumor development. acting as an intracellular iron carrier and protecting MMP9 from proteolytic degradation, NGAL has a clear pro-tumoral effect, as has already been observed in different tumors (e.g. breast, stomach, oesophagus, brain) in humans. In thyroid carcinomas, NGAL is strongly induced by NF-kB, an important factor involved both in tumor growth and in the link between chronic inflammation and neoplastic development. Thus, Lipocalin-2 (LCN2/NGAL) has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis.

Supplier: SWANN MORTON

Qlicksmart SnapIT is a simply safer way to open glass ampoules and avoid painful and dangerous sharps injuries. This easy-to-use multi-use ampoule opener avoids the unacceptable sharps injury rates seen when ampoules are opened by hand. L×W: 80×13 mm, 11 g. Plastic (body), Silicon (O-ring), Stainless steel (keyring and spring).

Supplier: MARKET SOURCE PART PROCESS

MAGPIX CALIBRATION KIT 1 * 1 KIT

Supplier: FISHER CONTAINER

CHEVRON PEEL POUCHES GAMMA IRRADIATED 1 * 1.000 items

Supplier: MP Biomedicals

Tris have been useful as buffers in a wide variety of biological systems. It has been used as a starting material for polymers, oxazolones (with carboxylic acids) and oxazolidines (with aldehydes). It does not precipitate calcium salts and is of value in maintaining solubility of manganese salts. It can be used for the direct standardization of a strong acid solution; the equivalence point can be determined either potentiometrically or by use of a suitable indicator such as 3-(4-Dimethylamino-1-naphthylazo)-4-methoxybenzenesulfonic acid. It is RNAse and DNAse-free. Tris is relatively non-hygroscopic ; but, if needed, it can be dried at 100 °C for up to 4 hours to remove any water.
Tris is used in pH control in vitro and in vivo for body fluids and in buffering systems for electrophoresis applications.Tris is used in assays used to characterize the activity and kinetics of the enzymes that catalyze SUMOylation of Small ubiquitin-like proteins (SUMO) and SUMO-dependent protein-protein interactions.

Supplier: Merck

Fast method development of complex samples across the pH range from 1,5 to 10,5 with different mobile phases and temperature conditions.
Purospher® STAR RP-18 endcapped HPLC columns are designed for universal use. Basic, neutral and metal-chelating compounds can easily be separated with simple mobile phases – naturally without peak tailing. Thanks to its outstanding performance and stability, Purospher® STAR RP-18 endcapped offers maximum flexibility in method development. Robust methods can be developed over the entire pH range from 1,5 to 10,5. High pH-stability allows the separation of strongly basic compounds with alkaline eluents. The combination of high purity silica, best all-round retention characteristics, outstanding pH stability up to pH 10,5, and suitability for up to 100% aqueous mobile phases, make Purospher® STAR RP-18 endcapped an all-round top performance column, almost universal in its range of applications.