17671 Results for: "Cy3+phosphoramidite&pageNo=30&view=easy"

Supplier: ProSci Inc.

This antibody recognises human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. It is also reactive with the immuno-dominant A trisaccharide. Blood group antigen expression in human colon cancer was studied by means of two monoclonal antibodies of broad anti-A (HE-14) and anti-type 3 and type 4 chain-based A and H (HE-10) specificity. These antigens were proved to re-appear in tumors of the distal colon, the HE-10 antibody reacting more frequently (9 out of 12 samples) than HE-14 (5 out of 12 samples) and frequently with supra-nuclear staining of the cytoplasm probably in those places of the Golgi apparatus where carbohydrate antigens are synthesised. This staining pattern is characteristic of HE-10 in normal colonic mucosa as well. With HE-14, staining was often absent in less differentiated tumors, while HE-10 did react in such tumors. In some cases, these two antibodies gave different staining patterns in parallel sections from the same tissue sample, primarily at the cellular level. Three out of 12 cases showed blood group antigen expression in the mucosa of the distal colon adjacent to the tumor only when HE-10 mAb was used.

Supplier: MEMMERT

IQ/OQ/PQ CHECK LIST WORK TEST DATA F.IFBW 1 * 1 items

Supplier: Roth Carl

Double spoon 1 * 1 items

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1201W Class 10 (M2.5), powderfree Length 12 (300mm), white 1 * 1.000 items

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1203W Class 10 (M2.5), powderfree Length 12 (300mm), white 1 * 1.000 items

Supplier: Amarell

Refill-Therm. AMA-Exact, -10+150:1C, enclosed scale, cap. colourless, red special liquid, richter-top finish without button, lower part 300x8-8,5mm, upper part 250xc.10mm, suitable for government verification, null

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1204W Class 10 (M2.5), powderfree Length 12 (300mm),colour white 1 * 1.000 items

Supplier: Amarell

Thermometer similar to BS 1365, BS35C/total, 25+35:0,1C, solid stem, white backed, capillary tube specially coated inside, with no n-wetting blue special liquid, 235mm long, total immersion, durable pigment, null

Supplier: MEMMERT

IQ/OQ/PQ CHECK LIST WORK TEST DATA F.IFBW 1 * 1 items

Supplier: Amarell

Metal ferrules, DIN 12787 mounted on Viscometer therm., Vogel-Ossag 1 * 1 items

Supplier: IKA

CHILLER RECIRCULATING RC 2 GREEN CONTROL 1 * 1 items

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1205W Class 10 (M2.5), powderfree Length 12 (300mm),colour white 1 * 1.000 items

Supplier: Amarell

Thermometer similar to BS 1900, SR6/34C, 16+34:0,05C, length 480mm, total immersion, solid stem, white backed, capillary tube spec ially coated inside, with non-wetting blue special liquid, with ice point scale, null

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1201B Class 10 (M2.5), powderfree Length 12 (300mm) 1 * 1.000 items

Supplier: Hettich

DRAWER EXCH.,SS,TELE RAIL, MAX.LOAD 40KG 1 * 1 items

Supplier: Amarell

Density hydrometer, 1,060-1,120:0,001g/cm , ref. temp. 20C, with therm., 350mm long, special liquid 1 * 1 items

Supplier: OMEGA BIO-TEK

E.Z.N.A.® Plant RNA kit provides a convenient and rapid method for the isolation of total RNA from a variety of plant samples. This kit provides a homogeniser column for filtration and homogenisation of viscous plant cell lysate by centrifugation in combination with the HiBind® RNA spin column for RNA purification. All the contaminants including polysaccharides and phenolic compounds are effectively removed. Purified RNA can be used for most downstream applications such as RT-PCR, northern blot analysis, differential display, and poly(A)+ RNA selection.

Supplier: OMEGA BIO-TEK

The E.Z.N.A.® Universal Pathogen Kit allows for the rapid and reliable isolation of high quality host genomic DNA, gram positive and negative bacterial DNA, fungal spore DNA and viral DNA and viral RNA from tissue, urine, serum and fecal samples.

Supplier: DEUTSCH NEUMANN

Tubing, red rubber, diameter(innerx outer)3x 6 thick 1.5mm. 1 * 25 m

Supplier: BANDELIN-ELECTRONIC

SONOREX SUPER RK 100, ULTRASONIC BATH, 35 KHZ, 230 V 50/60 HZ, ID 240X140X100 MM 3 L, S/S TIMER 1-15 MIN AND CONTINUOUS, ULTRASO NIC PEAK OUTPUT 320 W, HF-OUTPUT: 80 WEFF. 1 * 1 items

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1204B Class 10 (M2.5), powderfree Length 12 (300mm), colour blue 1 * 1.000 items

Supplier: Amarell

Soil therm., British type, similar specification, right angle, -7+38:0,5C, solid stem, white backed, red special liquid, round bulb with diameter 11,5-14,0mm, built-in length 75mm (MK2B), lower part 100mm, suitable for government verification 1 * 1 items

Supplier: ProSci Inc.

Antibodies are produced by B lymphocytes, each expressing only one class of light chain. Once set, light chain class remains fixed for the life of the B lymphocyte. In a healthy individual, the total kappa to lambda ratio is roughly 3:1 in serum (measuring intact whole antibodies) or 1:1.5 if measuring free light chains, with a highly divergent ratio indicative of neoplasm.

Individual B-cells in lymphoid tissue possess either kappa or lambda light chains, but never both together. Specific rearrangement of lambda light chain of immunoglobulins can lead to loss of some protein coding genes, which does not seem to be functionally relevant (while functionally relevant miR-650 can be overexpressed). Using immunohistochemistry, it is possible to determine the relative abundance of B-cells expressing kappa and lambda light chains. If the lymph node or similar tissue is reactive, or otherwise benign, it should possess a mixture of kappa positive and lambda positive cells. If, however, one type of light chain is significantly more common than the other, the cells are likely all derived from a small clonal population, which may indicate a malignant condition, such as B-cell lymphoma. [Wiki].

Supplier: ProSci Inc.

This antibody is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound protein. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product C4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival. C4d antibody, combined with antibody to C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Supplier: ProSci Inc.

This mAb recognises a protein of 41 kDa, which is identified as TDP2, or ETS1 associated protein II. It is a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. catalyses the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

Supplier: ProSci Inc.

This mAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer s cells of the liver and Langerhan s cells of the skin. Macrophages comprise of many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone marrow. After passing through the monoblast and pro-monocyte states of the monocyte stage, they enter the blood, where they circulate for about 40 hours. They then enter tissues and increase in size, phagocytic activity, and lysosomal enzyme content becoming macrophages. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, specific phagocytosis of opsonized microorganisms mediated by Fc receptors and complement receptors, killing of ingested microorganisms, digestion and presentation of antigens to T and B lymphocytes, and secretion of a large number of diverse products, including many enzymes including lysozyme and collagenases, several complement components and coagulation factors, some prostaglandins and leukotrienes, and many regulatory molecules (Interferon, Interleukin 1). LN-5 selectively stains human sebaceous glands in formalin-fixed, paraffin-embedded skin samples. Undifferentiated sebocyte progenitors are negative, and only sebocytes from the onset of their differentiation reveal positive cytoplasmic staining. Since there are very few selective and easy-to-use markers of sebaceous glands, LN-5 antibody can offer a simple and relatively specific way to detect human sebocytes from the onset of their.

Supplier: VELP SCIENTIFIC

The UDK Series distillers are designed to meet the most challenging demands and requirements for diverse applications, according to international standards: Kjeldahl nitrogen TKN, proteins, ammoniacal nitrogen, nitric nitrogen (Devarda), phenols, TVBN and volatile acids, cyanides, and alcohol content. Five different UDK models are available with different automation levels to match any laboratory requirement of automation and throughput. A complete range of distillers featuring exclusive technologies to meet any laboratory requirement for the determination of analytes in different fields of application.

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1202W Class 10 (M2.5), powderfree Length 12 (300mm), white 1 * 1.000 items

Supplier: TECHNI GLOVE

Nitrile glove 30cm TechniGlove TN1205B Class 10 (M2.5), powderfree Length 12 (300mm), colour blue 1 * 1.000 items

Supplier: Roth Carl

DISINFECTION TUB MADE OF PVC 30L KLA 1 * 1 items