51334 Results for: "Cover+Glasses"

Supplier: Lovibond Tintometer

Two spectrophotometric colorimeters that each include several of the popular scales that meet the requirements of objective colour analysis of oils, chemicals, fuels and other transparent products. The PFXi 950 instruments are rugged colorimeters with fabricated steel housings, which function equally as QC instruments within the laboratory or on 24-hour operation in a production environment. The accuracy and repeatability of the colour data provided by these colorimeters ensures consistency in colour measurement, giving processors the confidence needed to make important decisions regarding raw materials and refining operations.

Supplier: MP Biomedicals

Storage: +4 °C
D-Biotin is a growth factor present in small amounts in every living cell. It is involved in naturally occurring carboxylation reactions. It occurs mainly bound to proteins or polypeptides. It is more abundant in the liver, kidney, pancreas, yeast and milk. Biotin levels are higher in cancerous tumors than in normal tissues. It is inactivated by binding to avidin.
D-Biotin may be used to elute proteins from avidin/streptavidin resins. It is widely used for dietary supplements and fortified foods. It is also used for tablets and hard-shell capsule preparation due to its pharmaceutical properties.
Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.
Soluble in water (22 mg/100 mL), ethanol (80 mg/100 mL), more soluble in hot water and in dilute alkalies; insoluble in other common organic solvents. Soluble in 2 M Ammonium hydroxide (50 mg/mL - clear, colorless solution), dimethylformamide (1.7 mg/mL).

Supplier: VWR Collection

These compressor-cooled incubators provide a temperature range between –10 to +100 °C with forced air convection and fan speed control (10 to 100%). Featuring a stainless steel (DIN 1.4301) inner chamber and a powder coated sheet exterior. PREMIUM models have an intuitive menu and user friendly software, USB port with flash drive for data download to USB stick and for uploading programs. They can be connected to Ethernet or Wi-Fi network for remote control from any computer and users can receive notifications about selectable parameters via e-mail.

Supplier: Thermo Fisher Scientific

Heratherm™ large capacity incubators were designed to prevent samples drying out. All models have a large, easy to view, vacuum fluorescence display and simple to use touch button operation which is controlled by a microprocessor and automatic over-temperature alarm system to protect samples.

Supplier: Azbil Telstar Technologies

The ergonomically designed BiOptima Class II microbiological safety cabinet ensures optimum efficiency and high-level energy savings. BiOptima provides operator protection with the inflow air barrier, product protection thanks to HEPA-filtered laminar downflow in the working area and environmental protection through the exhaust HEPA filter.

Supplier: Thermo Fisher Scientific

D-(+)-Camphor ≥98%

Supplier: LABCONCO

These portable systems provide user protection by keeping powders and particulates contained during weighing procedures. The built-in blower and HEPA filter are mounted in the upper plenum to save space, and the enclosures have low installation costs and require no outside ducting. Systems also provide quiet operation as low as 45 dBA, depending on face velocity.

Supplier: MP Biomedicals

Storage: Room Temperature, desiccate
Protamine sulfate is a purified mixture of simple protein principles obtained from the sperm or testes of suitable species of fish, which has the property of neutralizing heparin. Because of having many basic amino acids (mostly arginine) protamine contains far greater nitrogen than other proteins. Its molecular weight is relatively small. Histone and other basic proteins in the testes of unmatured fishes convert into protamine along with the growth of the fishes. In the testes, protamine takes the form of nucleoprotamine linked with DNA.
Protamine Sulfate is a raw material for study preparations like insulin compounds, and etc. It is used in separation and refining of vaccines. It is a reagent for removing nucleic acids from enzyme solution for the purpose of easy separation and refining. Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Inhibits lipoprotein lipase. Protamine sulfate shown to inhibit the classical pathway of complement. It inhibits turnover of lipoproteins by lipoprotein lipase.

Supplier: MP Biomedicals

Storage: Store at Room Temperature (15-30 °C).
Ethylenediamine Tetraacetic Acid is a polyamino carboxylic acid hexadentate ligand and a chelating agent. This product is designated as Molecular Biology grade and is suitable for molecular biology applications.
Ethylenediamine Tetraacetic Acid is a chelator of divalent cations. It also inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Supplier: MP Biomedicals

Storage: Store at room temperature (15-30 °C)
L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine. L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.
L-Lysine monohydrochloride is a key amino acid in calcium absorption.

Supplier: Cayman Chemical

ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.

Supplier: IKA

TWISTER is a universal and compact mixing device with magnetic drive. In the default version, TWISTER is a powerful single-position magnetic stirrer for mixing up to 5 litres at a maximum speed of 3000 min⁻¹ and a viscosity of up to 500 mPa·s. By connecting additional TWISTER stirring units (available as accessories, IKAA20112621), TWISTER can be expanded to a multi-position magnetic stirrer with up to 30 stirring positions. The stirring positions can be controlled either separately or simultaneously (leader-follower principle).

Supplier: MP Biomedicals

Storage: Store at Room Temperature (15-30 °C)
Glycine is a non-essential amino acid. It is only amino acid with no asymmetric carbon and thus is not chiral. It is the major inhibitory neurotransmitter. It is involved in the biosynthesis of the porphyrin rings of hemes and chlorophylls.
Glycine is commonly used in buffer solutions, in electrophoresis and preparative chromatography. A study of the folding of monoclonal antibodies in the presence of glycine and their subsequent purification has been published. The use of glycine in the purification of lipopolysaccharides, lipooligosaccharides, and lipid A has been reported. It is an amino acid for use in cell culture media development applications and existing media formulations. Glycine is commonly used as a component in Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis, a component of Towbin's transfer buffer for Western blots, a buffer substance in cryoenzymology, in osmotic pressure maintenance in isoelectric focusing of erythrocytes, salting-in effect in protein chemistry, and as a buffer component in the coupled phosphatase-kinase reaction for end labelling of restriction fragments. The growth requirements of various microorganisms is reported in the Handbook of Microbiology.
Glycine is a non-chiral amino acid that can be synthesized in the body from the amino acid serine by Serine Hydroxymethyltransferase. Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Supplier: Lovibond Tintometer

The PFXi 995 spectrophotometers are top of the range, versatile instruments that offer comprehensive colour data requirements for either the Petrochemicals industry or the Food and Chemicals industries for edible oils, fats, chemicals etc. The PFXi 995 and PFXi 995/P provide objective, unbiased colour data according to a comprehensive range of established industry scales, spectral data and CIE values. They are ideal for companies that process a broad selection of product types with varied colour specifications, particularly in central test facilities or in independent testing laboratories. The instruments are easily customised to display only those scales of interest to the user.

Supplier: MP Biomedicals

Storage: Store at -20 °C.
Brefeldin A is a fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. Produced by Penicillium brefeldianum. Blocks binding of the cytosolic coat protein b-COP and ARF to Golgi membranes mediated by protein G. Also blocks protein transportation into post-Golgi compartments. It activates the sphingomyelin cycle. Brefeldin A mediated apoptosis has been observed in human tumor cells.
Brefeldin A reversibly inhibits the intracellular translocation of proteins in eukaryotes, e.g., during transport of proteins to the cell surface for secretion or expression. It has been reported to block the response of cultured cells to cholera toxin. In HepG2 cells, BFA induces two blocks in the secretory pathway; one at the level of the endoplasmic reticulum-Golgi juncture and the other in the trans-Golgi network. Brefeldin A is used in the studies of Brefeldin A-inhibited Guanine Nucleotide-exchange Protein, BIG2, Regulates the Constitutive Release of TNFR1 Exosome-like Vesicles.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.

Supplier: Molekula

D-(+)-Camphor

Supplier: MP Biomedicals

Applications:
Urea is used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies and in the extraction of the mitochondrial complex. It is commonly used to solubilize and denature proteins for denaturing isoelectric focusing and two-dimensional electrophoresis and in acetic acid-urea PAGE gels. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form. Urea is used in cell or tissue culture media to increase the osmolality. Urea has also been used as fertilizer because of the easy availability of nitrogen; in animal feeds; it is reacted with aldehydes to make resins and plastics; condensed with malonic ester to form barbituric acid; used in the paper industry to soften cellulose.
Biochem/physiol Actions:
Urea has been shown to act as an aldosterone antagonist in the development of peanut agglutinin binding in cultured embryonic renal collecting duct epithelial cells. Urea is the principal end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle.
Typical Working Concentration:
The use of 2 g/L urea in the culture of Kluyveromyces marxianus to produce a thermostable extracellular lipase has been described. Urea is typically used at a concentration of 8 M for protein denaturation or solubilization. A final concentration of 5 M urea is commonly used in molecular biology for sequencing gels. To prevent carbamylation, do not heat urea containing buffers above 37 °C

Supplier: MEMMERT

The ICO series of CO₂ incubators has seamlessly welded, corrosion-resistant stainless steel chambers with rounded edges and no further installations, ensuring easy and thorough cleaning. Models have TwinDISPLAY with a USB port for uploading programs, reading out logs or protecting appliances via the user ID function, and an Ethernet interface as well as a data logger with a 10 year storage capacity. All parameters can be set directly in the ControlCOCKPIT or the AtmoCONTROL software, which uses drag and drop symbols to input values. Battery-buffered ControlCOCKPIT (optional): Operating display, logging and CO₂ control are fully functional even during a power failure.

Supplier: Azbil Telstar Technologies

The ergonomically designed BiOptima Class II microbiological safety cabinets ensure optimum efficiency and high-level energy savings. BiOptima EXA provide operator protection by inflow through the front grill, product protection by HEPA-filtered laminar downflow in the working area (100% exhaust) and environmental protection via HEPA-filtered exhaust air (not included with the cabinet). BiOptima EXA is designed for hazardous airborne application such as volatiles, mists or vapours beside high microbiological and hight toxic applications. Designed according to NSF 49. This model is available as standard in widths of either 4 or 6' (120 and 180 cm approx.).

Supplier: MP Biomedicals

Storage: Store at +4 °C, store under nitrogen
Glutathione is the major low molecular weight thiol compound of the living plant or animal cell. It is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. The sulfhydryl (thiol) group (SH) of cysteine serves as a proton donor and is responsible for the biological activity of glutathione.
Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Supplier: OMEGA BIO-TEK

The E.Z.N.A.® Universal Pathogen Kit allows for the rapid and reliable isolation of high quality host genomic DNA, gram positive and negative bacterial DNA, fungal spore DNA and viral DNA and viral RNA from tissue, urine, serum and fecal samples.

Supplier: Thermo Fisher Scientific

Sodium deoxycholate monohydrate ≥98%

Supplier: PanReac AppliChem

L(+)-Cysteine hydrochloride monohydrate

Supplier: Azbil Telstar Technologies

The ergonomically designed BiOptima Class II microbiological safety cabinets ensure optimum efficiency and high-level energy savings. BiOptima provides operator protection with the inflow air barrier, product protection thanks to HEPA-filtered laminar downflow in the working area and environmental protection through the exhaust HEPA filter. BiOptima Cyto is available in 120 or 180 cm (4 or 6’) widths as standard.

Supplier: BioAir S.p.A.

Safemate ECO+ Cabinets are supplied in four different sizes (0.9, 1.2, 1.5 and 1.8). These last generation Microbiological Safety Cabinets Class II type A2, have been certified according to the most stringent safety standards (EN 12469-2000). The internal design, the air flow aerodynamics and monitoring, the built-in safety devices and the very accurate manufacturing, guarantees the highest performances at the most stringent safety levels, as specified by EN 12469 standard and have been certified by the most prestigious European certification bodies for Safety Cabinets.

Supplier: Thermo Fisher Scientific

The Pierce™ yeast DNA extraction reagent kit uses Y-PER yeast protein extraction reagent to quickly extract and purify genomic and plasmid DNA from yeast.

Supplier: Heidolph Instruments GmbH & Co.KG

Hei-VAP Expert Control rotary evaporators allow central control of all process parameters: Vacuum, cooling temperature, rotation and heating bath temperature. The units have separate knobs for quick access: Right for direct vacuum control, the left one for rotation has a lock function to prevent accidental adjustment

Supplier: VELP SCIENTIFIC

The FIWE Advance is a fully automatic analyser for Crude and Detergent Fibre determination according to official reference methods. State of the art technology ensures safety, premium remote connectivity and a unique user experience. FIWE Advance Load and Go operation, requires minimum operator time, just 2 minutes, to improve productivity.

Supplier: IKA

EasySyn is the reactor system for organic or aqueous syntheses, and the only reactor system for which you can get all the complementary components from a single source: Overhead stirrers, circulators, vacuum pumps and controllers, sensors and automation software. All from IKA and all perfectly matched to each other. With its double-walled reactor vessels from 500 to 5000 ml, EasySyn is a medium-sized and very flexible upscaling system. It ensures safe and reproducible chemical reactions.

Supplier: MP Biomedicals

Poly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.