48194 Results for: "Concanamycin+A&pageNo=8"

Phospholipase A2 inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose. Disrupts membrane tubule-mediated reassembly and maintenance of the Golgi complex.

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G1883A network headspace supplies

Supplier: Agilent

Needle for transfer line, nickel, 0,4 mm ID, 0,8 mm OD

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2,2,4,4-Tetramethylpentane ≥98%

Supplier: Thermo Fisher Scientific

2,2,4,4-Tetramethylpentane ≥98%

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2,2,5,5-Tetramethyl-3-pyrrolin-1-oxyl-3-carboxylic acid N-hydroxysuccinimide ester, 98% 1 * 1 g

Supplier: Thermo Fisher Scientific

2,2,5,5-Tetramethyl-3-pyrrolin-1-oxyl-3-carboxylic acid N-hydroxysuccinimide ester, 98% 1 * 1 g

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Necrostatin-7 ≥98% (by HPLC, TLC)

Supplier: ENZO LIFE SCIENCES

Necroptosis inhibitor

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5,5-Dimethyl-1-pyrroline-N-oxide ≥98% (by ELSD)

Supplier: ENZO LIFE SCIENCES

Spin trapping reagent

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HET-0016 ≥98%

Supplier: ENZO LIFE SCIENCES

Cytochrome P450 inhibitor

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2-Bromobutane ≥98%

Supplier: Thermo Fisher Scientific

2-Bromobutane ≥98%

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2-(Pyridin-3-yl)acetic acid hydrochloride ≥98%

Supplier: Thermo Fisher Scientific

2-(Pyridin-3-yl)acetic acid hydrochloride ≥98%

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trans-7-Hydroxy-PIPAT maleate ≥98%, white solid

Supplier: ENZO LIFE SCIENCES

Dopamine receptor ligand.

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BIBB-515 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

BIBB 515 is a potent and selective inhibitor of 2,3-oxidosqualene cyclase (OSC) in vivo. BIBB 515 inhibits LDL production in both normolipemic and hyperlipemic hamsters and may represent a novel approach for the development of lipid lowering drugs.

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Ethylenetetracarbonitrile ≥98%

Supplier: Thermo Fisher Scientific

Ethylenetetracarbonitrile ≥98%

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trans-3,4-Dichloro-β-nitrostyrene ≥98%

Supplier: Thermo Fisher Scientific

trans-3,4-Dichloro-β-nitrostyrene ≥98%

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1,9-Pyrazoloanthrone ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Potent, cell permeable, selective, and reversible inhibitor of c-Jun N-terminal kinase (JNK) (IC50=40nM for JNK-1 and JNK-2 and 90nM for JNK-3). The inhibition is competitive with respect to ATP. Exhibits over 300-fold greater selectivity for JNK as compared to ERK1 and p38. Inhibits the phosphorylation of c-Jun and blocks the expression of IL-2, IFN-γ, TNF-α, and COX-2. Blocks IL-1-induced accumulation of phospho-Jun, induction of c-Jun transcription and anti CD3-induced apoptosis of CD4+ CD8+ thymocytes.

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Tributylamine 98%

Supplier: Thermo Fisher Scientific

Tributylamine 98%

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Diphenylboric acid-2-aminoethyl ester (2-APB) ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Cell permeable modulator of Ins(1,4,5)-P3-induced Ca²⁺ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca²⁺ entry (75µM).