3803 Results for: "Comparator+Kits&pageNo=72"

Supplier: ProSci Inc.

During vertebrate embryogenesis, a left-right axis is established. Secreted growth factors of the TGF-beta family, including gene products derived from nodal, lefty-1 and lefty-2, play crucial roles in establishing left-right asymmetries. TGF-beta (Transforming growth factor-beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells. TGF-beta actions are directed by ligand-induced activation of TGF-beta receptors. Complexes formed move into the nucleus, where they act as components of a transcriptional complex. Lefty, a novel member of the TGF-beta superfamily, inhibits TGF-beta signaling. Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF-beta receptor. Lefty also inhibits events downstream from R-Smad phosphorylation. Lefty provides a repressed state of TGF-beta-responsive genes. The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, and Lefty A and Lefty B in humans. Members of the TGF-beta superfamily require processing for their activation. Cleavage is therefore an essential step for Lefty activation. Lefty is synthesized as a large inactive precursor (42 kDa) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms). The 28 kDa form induces MAPK activity.

Supplier: JOUAN

KIT CONTRACT/REL OVEN EU500/720 1 * 1 items

Supplier: ProSci Inc.

Jagged-1 (JAG1) is a cell surface protein which is one of several ligands that activate Notch and related receptors. JAG1 functions in an embryologically important signaling pathway and has also been shown to play a role in hematopoiesis. JAG1 inhibits proliferation of cd34+ macrophage progenitor cells and a JAG1 gene abnormality may be an aggravating factor in extrahepatic biliary atresia. Activation of NOTCH1 signaling by JAG1 induces monocyte-derived dendritic cell maturation in vitro. JAG1 interaction with NOTCH1 on tumor cells dramatically induces proliferation and inhibition of apoptosis in vitro. Either haploinsufficiency for wild-type JAG1 and/or dominant negative effects produced by mutated JAG1 are responsible for the Alagille syndrome. A BLAST analysis was used to suggest crossreactivity with Jagged-1 protein from human, chimpanzee, rat and mouse based on 100% homology with the immunizing sequence. Partial reactivity is expected against canine (81%) and Xenopus laevis (85%) based on partial sequence homologies as indicated. The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Supplier: Thermo Scientific

Thermo Scientific CultiMaxx Shelving Systems are designed for use in Heracell VIOS 250i or Heracell Vios 250i Cleanroom CTS Series CO₂ incubators to support scale-out of Thermo Scientific™ Nunc™ Cell Factory™ systems in cell therapy production and are ideal for use with Wilson Wolf G-Rex® 500M-CS bioreactors, standard Nunc Cell Factory system or the Thermo Scientific™ Nunc™ EasyFill™ Cell Factory™ system, both with 4 layers.

Supplier: CUSTOM MADE CHEMICALS LAB

COMPONENTS MIX 5 1 * 5 Ampoul

Supplier: MACHEREY-NAGEL

Column, ChromCart HPLC guard CC 8/4 NUCLEOSIL 100-5 C18 AB length:8mm, ID:4mm pack of 3 suitable for analytical columns/Cartridge,s with 4 or 4.6mm ID:for EC columns by the use of guard Column, adapter EC (REF 721359)-for ChromCart Cartridge,s by th. 1 * 3 items

Supplier: MP Biomedicals

The SPINeasy® RNA Kit for Feces delivers high yields of pure RNA without detectable DNA contamination in less than 20 min, making it particularly suitable for downstream applications, such as qPCR and RT-qPCR without the need of further inhibitor/DNA removal steps.

Supplier: OMEGA BIO-TEK

The Mag-Bind® Blood and Tissue DNA HDQ 96 Kit is designed for rapid and reliable isolation of high quality genomic DNA from 100 to 200 μl blood samples, buccal swabs, buffy coat and cultured cells. All heating steps that limit robotic applications have been removed to allow for faster processing. Mag-Bind® particles HDQ provide quick magnetic response time reducing overall processing time. Utilising paramagnetic particles provides high quality DNA that is suitable for direct use in most downstream applications, such as qPCR, PCR and Next Generation Sequencing. The Mag-Bind® HDQ Blood DNA and Tissue 96 Kit is compatible with many robotic liquid handlers and magnetic processors, including Thermo Scientific KingFisher® Flex.

Supplier: Bohlender

Tri-Clamp Gaskets, Silicone ring with double-sided, elastic washer made of PTFE. Suitable for Tri-Clamp connections as per DIN 32 67 6. Universal chemical resistance, the flowing product is only exposed to PTFE. 1 * 1 items

Supplier: Cole-Parmer

FLEXIBLE JOINT 1 * 1 items

Supplier: Cole Parmer

Flask,receiving,500ml,Quickfit No. RE100/RF/500 1 * 1 items

Supplier: LABOR OPTIK

COUNTING CHAMBER F-R DOUBLE 1 * 1 items

Supplier: LABOR OPTIK

COUNTING CHAMBER B DOUBLE 1 * 1 items

Supplier: Cole-Parmer

EMEA 500ml 230V re cartridge 1 * 1 items

Supplier: LGC Standards PROMOCHEM

JWH-015 ((2-METHYL-1-PROPYLINDOL-3-YL)(NAPHTHALEN-1-YL)METHANONE) 1 * 10 mg

Supplier: Cole Parmer

Heater Block Clamp for Small Base 1 * 1 items

Supplier: LGC Standards PROMOCHEM

JWH-015 ((2-METHYL-1-PROPYLINDOL-3-YL)(NAPHTHALEN-1-YL)METHANONE) 0.1 MG/ML IN ACETONITRILE 1 * 1 mL

Supplier: LGC Standards PROMOCHEM

JWH-015 ((2-METHYL-1-PROPYLINDOL-3-YL)(NAPHTHALEN-1-YL)METHANONE) 1.0 MG/ML IN ACETONITRILE 1 * 1 mL

Supplier: NEUBERT VOLUME GLASSWAERE

FUNNEL SEPARATING 500ML GILSON NS29 TEF 1 * 1 items

Supplier: MARKET SOURCE PART PROCESS

ChemoLock Vented Vial Spike 13mm / Skirt design For Liquids 1 * 50 items

Supplier: Heidolph Instruments GmbH & Co.KG

RS 232 cable (9-pole) 1 * 1 items

Supplier: Heidolph Instruments GmbH & Co.KG

Vacuum sensor vacuum box (Hei-VAP Bench-top) (Index 1-2) 1 * 1 items

Supplier: Heidolph Instruments GmbH & Co.KG

PTFE inlet tube 3,5/4,5x1600 (Hei-VAP Bench-top) 1 * 1 items