Supplier: G-Biosciences

The OmniPrep™ kit isolates high quality genomic DNA from many different species and tissue types including animal, plant, bacteria, yeast, fungi, whole blood, and cells in culture. DNA can be isolated from samples high in polysaccharides or other contaminants that are difficult to remove from the DNA preparations.

Supplier: G-Biosciences

OmniPrep™ for Tissue Kit is to specifically isolate high quality genomic DNA from tissue samples, including fresh, frozen, fixed or paraffin-embedded tissue. The kit isolates DNA from bodily fluids, including plasma, serum, amniotic fluid, semen and CSF. Also isolates high quality DNA from cultured cells, non-mammalian nucleated blood and gram-negative bacteria.

Supplier: MP Biomedicals

The SPINeasy® RNA Kit for Feces delivers high yields of pure RNA without detectable DNA contamination in less than 20 min, making it particularly suitable for downstream applications, such as qPCR and RT-qPCR without the need of further inhibitor/DNA removal steps.

Supplier: MP Biomedicals

Host DNA contamination impedes the molecular analyses of microbiomes in host samples, such as bodily fluids and swabs. The SPINeasy Host Depletion Microbial DNA kit provides an easy-to-use workflow to isolate microbial DNA from samples containing high amounts of host DNA.

Supplier: MP Biomedicals

The MagBeads FastDNA Kit for Feces allows thorough sample lysis and quick isolation of DNA from fecal samples. It is using magnetic beads with high DNA binding capacity for extraction of high yields of pure DNA. This is done manually using a magnetic rack or adapted to automated instruments for high throughput processing.

Supplier: MP Biomedicals

The Fast DNA® SPIN Kit for Faeces quickly and efficiently isolates PCR-ready genomic DNA from fresh or frozen human and animal stool samples.

Supplier: MP Biomedicals

The Fast DNA™ SPIN Kit for Soil is designed to efficiently isolate bacterial, fungal, plant and animal genomic DNA from soil and other environmental samples. It quickly and efficiently isolates PCR-ready genomic DNA directly from soil samples in less than 60 minutes.

Supplier: Thermo Scientific

Available in glass or solid door, the TSX series high-performance refrigerators combine advanced microprocessor temperature control with high-quality cabinet construction and alarm systems. Positive, forced-air circulation is designed to maintain temperature uniformity to protect important medical and pharmaceuticalgrade storage as well as laboratory media, reagents and more. The Series’ V-drive technology is designed to provide temperature uniformity that continually adapts to user patterns, offering significant energy savings without compromising protection.

Supplier: Thermo Scientific

Thermo Scientific™ TSX Series high-performance pharmacy refrigerators are designed with features that support sample protection and sustainability objectives for the storage of pharmaceuticals, vaccines, chemotherapy and other medical and pharmacy-grade storage requiring 2 to 8 °C. The Series’ V-drive technology is designed to provide temperature uniformity that continually adapts to user patterns, offering significant energy savings without compromising protection. Certified to NSF/ANSI 456 Vaccine Storage standard, the TSX series can help you meet regulations and guidelines from the CDC, World Health Organisation, and other Health Ministries on vaccine storage and handling. The TSX Series delivers the performance and quality you need, in addition to the low sound, low energy, and exceptional user experience you deserve.

Supplier: Cytiva

illustra™ tissue and cells genomicPrep Mini Spin Kit is designed for the rapid extraction and purification of high quality genomic DNA from a variety of animal tissues and mammalian cell cultures. The kit can be used for several downstream applications including restriction enzyme analysis, ligation, cloning, DNA sequencing and PCR.

Supplier: Thermo Scientific

Thermo Scientific™ TSX Series high-performance pharmacy refrigerators are designed with features that support sample protection and sustainability objectives for the storage of pharmaceuticals, vaccines, chemotherapy and other medical and pharmacy-grade storage requiring 2 to 8 °C. The Series’ V-drive technology is designed to provide temperature uniformity that continually adapts to user patterns, offering significant energy savings without compromising protection. The Series’ V-drive technology is designed to provide temperature uniformity that continually adapts to user patterns, offering significant energy savings without compromising protection. Certified to NSF/ANSI 456 Vaccine Storage standard, the TSX series can help you meet regulations and guidelines from the CDC, World Health Organisation, and other Health Ministries on vaccine storage and handling. The TSX Series delivers the performance and quality you need, in addition to the low sound, low energy, and exceptional user experience you deserve.

Supplier: Biosensis

The amyloid beta peptide is derived from the cleavage of the Amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. However, the form(s) of amyloid-beta peptide (Aβ) associated with the pathology characteristic of Alzheimer’s disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal APP and not Aβ exclusively. MOAB-2 (mouse IgG2b) is a pan-specific, high-titer antibody to Aβ residues 1-4 as demonstrated by biochemical and immunohistochemical analyses (IHC), and is highly specific just to amyloid beta peptide. MOAB-2 did not detect APP or APP-CTFs in cell culture media/lysates (HEK-APPSwe or HEK APPSwe/BACE1) or in brain homogenates from transgenic mice expressing 5 familial AD (FAD) mutation (5xFAD mice). Using IHC on 5xFAD brain tissue, MOAB-2 immunoreactivity co-localized with C-terminal antibodies specific for Aβ40 and Aβ42. MOAB-2 did not co-localize with either N- or C-terminal antibodies to APP. In addition, no MOAB-2-immunreactivity was observed in the brains of 5xFAD/BACE-/- mice, although significant amounts of APP were detected by N- and C-terminal antibodies to APP, as well as by 6E10. In both 5xFAD and 3xTg mouse brain tissue, MOAB-2 co-localized with cathepsin-D, a marker for acidic organelles, further evidence for intraneuronal Aβ, distinct from Aβ associated with the cell membrane. MOAB-2 demonstrated strong intraneuronal and extra-cellular immunoreactivity in 5xFAD and 3xTg mouse brain tissues.

Supplier: GRAM

BioLine is a comprehensive refrigeration range designed to deal with special bioscience needs. BioLine is distinct from other 'spark-free' refrigerators on the market, as both the interior and the exterior of all units have been shown to comply with the European ATEX [EN/IEC60079-15] directive which means they are safe for use in potentially explosive atmospheres (Zone 2 [Category 3]). The unique air distribution system combined with a finned tube evaporator results in excellent temperature consistency for biostorage; the evaporator design eliminates the risk of 'cold walls', which can damage delicate items stored touching the sides of the cabinet. Whilst the air distribution system which directs the cold air down the rear of the cabinet and back up to the evaporator fan at the top, ensures a uniform temperature throughout - using only a minimum of energy. The use of both cyclopentane to foam the insulation material and also hydrocarbon refrigerants means that BioLine storage solutions have only minimal environmental impact.

Supplier: Biosensis

The amyloid beta peptide is derived from the cleavage of the Amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. However, the form(s) of amyloid-beta peptide (Aβ) associated with the pathology characteristic of Alzheimer’s disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal APP and not Aβ exclusively.

MOAB-2 (mouse IgG2b) is a pan-specific, high-titer antibody to Aβ residues 1-4 as demonstrated by biochemical and immunohistochemical analyses (IHC), and is highly specific just to amyloid beta peptide. MOAB-2 did not detect APP or APP-CTFs in cell culture media/lysates (HEK-APPSwe or HEK APPSwe/BACE1) or in brain homogenates from transgenic mice expressing 5 familial AD (FAD) mutation (5xFAD mice).

Using IHC on 5xFAD brain tissue, MOAB-2 immunoreactivity co-localized with C-terminal antibodies specific for Aβ40 and Aβ42. MOAB-2 did not co-localize with either N- or C-terminal antibodies to APP. In addition, no MOAB-2-immunreactivity was observed in the brains of 5xFAD/BACE-/- mice, although significant amounts of APP were detected by N- and C-terminal antibodies to APP, as well as by 6E10. In both 5xFAD and 3xTg mouse brain tissue, MOAB-2 co-localized with cathepsin-D, a marker for acidic organelles, further evidence for intraneuronal Aβ, distinct from Aβ associated with the cell membrane. MOAB-2 demonstrated strong intraneuronal and extra-cellular immunoreactivity in 5xFAD and 3xTg mouse brain tissues.

Biosensis now offers biotinylated MOAB-2 antibody allowing more flexibility in experimental design by using the biotin-avidin/streptavidin detection method. Biotinylated MOAB-2 antibody may also help to reduce background staining in difficult-to-stain tissues and increase detection sensitivity. The ability of biotinylated MOAB-2 antibody to detect amyloid beta has been validated by IHC.

Supplier: MOLECULAR DEVICES

The ImageXpress® HCS.ai High-Content Screening System captures your imagination with high-quality imaging and analysis, enabling you to acquire the data you need with ease.