13930 Results for: "Calcium+sulphate"

Supplier: SHERWOOD SCIENTIFIC INSTRUMENT

Calibration standard1000ppmCalcium 6 x 100ml pk 1 * 600 mL

Supplier: Biorbyt

S100A11 Human Recombinant is expressed in E.coli having molecular weight of 17kDa fused to an amino terminal hexahistidine tag. 1 * 2 µG

Supplier: Biorbyt

S100B Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain fused to GST tag and having total molecu lar mass of 36kDa. The S100B is purified by proprietary chromatographic techniques. 1 * 2 µG

Supplier: Biorbyt

The Recombinant Human S100P has molecular mass of 10.4 kDa containing 95 amino acid residues of the human S100P.MTELEAAMGM IIDVFSRYS G SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK. 1 * 10 µG

Supplier: Enzo Life Sciences

CaMKIIa, the alpha subunit of Ca2+ calmodulin-dependent protein kinase II is part of a family of multifunctional protein kinases, which play a major role in Ca2+-mediated signal transduction.  CaMKIIa is expressed in many different tissues but is specifically found in the neurons of the forebrain and its mRNA is found within the dendrites as well as the soma of the neuron.  The neuronal CaMKII consists of two major subunits of 52 and 60 kDa which are encoded by a- and b-CaMKII genes, respectively.  Additional isoforms are generated by alternative splicing of these as well as of the ubiquitious g- and d-CaMKII genes.  Each subunit has an ATP-binding domain (arginine-X-X-serune/threonine), consensus phosphorylation site, catalytic domain, and a centrally located regulatory domain which has calmodulin binding activity. Activation and autophosphorylation of CaMKII may regulate numerous neuronal processes which includes two forms of synaptic plasticity, long term potentiation and long term depression.  Neuronal CaMKII subunits assemble as large multimeric holoenzymes.  The C-terminal association domains of  6-12 subunits assemble into a central globular structure from which the N-terminal catalytic/regulatory domains extend radially like petals of a flower. The subunit composition of the rat forebrain CaMKII holoenzyme consists of heteromers composed of a and β subunits at a ratio of 2:1 and homomers composed of only a subunits.  The association of CaMKII subunits leads to the positioning of their catalytic/regulatory domains in close proximity and the neighboring calmodulin-bound subunits cooperate to rapidly phosphorylate each other.  Autophosphorylation also enables CaMKII to attain an enhanced affinity for NMDA receptors in postsynaptic densities.

Supplier: Thermo Orion

This rugged, waterproof portable meter is designed for a wide range of pH, ion concentration, mV, ORP and temperature testing and field applications. It can be used in the most demanding locations thanks to its IP 67-rated housing. The meter offers one measuring channel.

Supplier: Enzo Life Sciences

CaMKII (calmodulin-dependent kinase II) is an enzyme which is activated by increases in intracellular Ca2+ ion concentration and it has been proposed to be pivotal in regulating synaptic strength and maturation of synapses during development.  This process is thought to be critical in memory and learning and in establishing the specificity of synaptic connections. There are over two dozen alternative splice variants of CaMKII which are encoded by four genes, a, b, g, and d with apparent molecular masses of 50-60 kDa.  CaMKII is widely distributed in many tissues, but is highly expressed in brain. Several studies demonstrate that CaMKII is a multifunctional enzyme which modulates the synaptic strength by binding to a subunit of NMDA receptors and promoting the phosphorylation of this NMDA receptor subunit.  CaMKII also regulates DLG localization at synapses by co-localization with DLG in the same protein complex.  Experimental data suggest that CaMKII is critically involved in the development of morphine tolerance as well as dependence and inhibition of this enzyme may have some therapeutic benefit in the treatment of opiate tolerance and dependence.  It also has been demonstrated that d CaMKII isozyme is down-regulated in human tumor cells indicating a role for d CaMKII isozymes in cellular differentiation.  Changes in d CaMKII isozyme expression pattern in human hearts during heart failure suggest that CaMKII is important for regulation of heart function.  This immunoaffinity purified antibody detects proteins of 50-60 kDa, corresponding to apparent molecular mass of CaMKII isoforms on SDS-PAGE immunoblots, in samples from human, mouse, rat, bovine, hamster, guinea pig, chicken and rabbit origins. Recombinant rat calmodulin-dependent protein kinase II a subunits expressed in sf9 insect cells are also detected. As the sequences of the rat a, d, and g isoforms are conserved over this amino terminus region, this antibody is expected to recognize the d, g and a isoforms. This antibody is not expected to cross-react with the b isoform. Proteins of unknown identity, ~40, 45 and 90 kDa, may be detected on immunoblot analysis with some lysates.

Supplier: MACHEREY-NAGEL

Spare syringe C 20/SBV VISOCOLOR. 1 * 1 items

Supplier: CUSTOM MADE CHEMICALS LAB

11 COMPONENTS MIX 1 * 500 mL

Supplier: Thermo Orion

These bench top meters record accurate and reliable pH, ion concentration, mV, ORP and temperature measurements. They are ideal for a wide range of applications and advanced pH or ion analysis in the lab.