21375 Results for: "CENTA\\u2122+\\u03B2-Lactamase+Substrate"

Supplier: ENZO LIFE SCIENCES

Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.

Supplier: ENZO LIFE SCIENCES

Highly quenched and sensitive fluorogenic MMP substrate

Supplier: ENZO LIFE SCIENCES

This peptide, Biotin-Ahx-EEEEAYGWLDF, is derived from gastrin and can be used as a substrate for KDR/VEGFR2.

Supplier: ENZO LIFE SCIENCES

This peptide, Biotin-Ahx-PKTPKKAKKL, is derived from histone H1 and is a substrate for CDK5.

Supplier: ENZO LIFE SCIENCES

This peptide sequence, RRApTVA, has been found to be an excellent substrate for both PP2A and PP2C phosphatases.

Supplier: ENZO LIFE SCIENCES

This peptide, EFGTYGTLSKKK, is derived from a peptide (pF4) discovered, through phage display, to be a very good substrate for Fyn kinase.

Supplier: THERMO FISHER DIAGNOSTICS

Broad Spectrum Beta Lactamase mixture, Application: Bacteria, beta lactamase, Freeze-dried

Supplier: ENZO LIFE SCIENCES

The HIGHDEF® DAB Chromogen/Substrate Set can be used in conjunction with peroxidase-based immunostaining systems. Peroxidase from the antibody detection system reacts with hydrogen peroxide substrate to degrade it, which then reacts with DAB, precipitating it at positive sites and yielding a dark brown color.

Supplier: ENZO LIFE SCIENCES

Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).

Supplier: ENZO LIFE SCIENCES

This peptide, Biotin-Ahx-GGMEDIYFEFMGGKKK, identified by screening a degenerate peptide library, is a substrate for several kinases, including HER-2/c-neu/erb-B-2, Tie-2, cFMS, and cKit.

Supplier: ENZO LIFE SCIENCES

Quenched fluorogenic substrate for cathepsin D (kcat/Km=1,09×10 M-1s-1) and cathepsin E (kcat/Km=1,56×10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.

Supplier: ENZO LIFE SCIENCES

Fluorometric substrates for assaying activities of members of caspase family proteases. All substrates are provided in liquid ready-to-use form.

Supplier: ENZO LIFE SCIENCES

This peptide, EAIYAAPFAKKK, was identified as a high affinity (Km=4 µM) and specific substrate for the Abl kinase through a degenerate peptide library.

Supplier: ENZO LIFE SCIENCES

This peptide, YIYGSFK, was derived through a random combinatorial peptide library method and is a specific and efficient substrate for the scr family of kinases. The Km of YIYGSFK for p60c-src is 55 µM.

Supplier: ENZO LIFE SCIENCES

This peptide, Biotin-Axh-HHASPRK, is a specific substrate for CDK2. The biotin allows the peptide to be used in kinase assays with streptavidin-bound membranes.

Supplier: ENZO LIFE SCIENCES

Fluorogenic substrate for several matrix metalloproteinases (MMPs).

Supplier: ENZO LIFE SCIENCES

This peptide, KKKKERLLDDRHDSGLDSMKDEE, was derived from the IkappaBalpha sequence.

Supplier: ENZO LIFE SCIENCES

This peptide sequence, RRFKRQGSFFYFF, was selected from a peptide library for optimal phosphorylation by protein kinase C zeta (PKCζ).

Supplier: ENZO LIFE SCIENCES

Sensitive fluorogenic substrate for TACE (TNFalpha converting enzyme, ADAM17). Also cleaved by ADAM10 and likely other ADAMs and MMPs. The kcat/Km of TACE for this substrate is 7-fold higher than for the same peptide with the Mca-Dpa fluorophore-quencher pair. FAM fluorescence is quenched by the TAMRA group until cleavage separates them. Ex.: 485 nm, Em.: 535 nm, although the following Ex/Em can also be used: 490,494/515,520 nm. This substrate is useful for inhibitor screening, kinetic analysis, and cellular activity assay.

Supplier: ENZO LIFE SCIENCES

This peptide (also known as Woodtide), KKISGRLSPIMTEQ, is derived from transcription factor FKHR with the addition of two lysines to facilitate binding to phosphocellulose membranes. It is a substrate for the DYRK family of kinases.

Supplier: ENZO LIFE SCIENCES

This peptide sequence, KKKVSRSGLYRSPSMPENLNRPR, corresponds to amino acids 206 to 225 of the phosphatase CDC25C, which is a phosphorylation target of Chk1 on Ser216.

Supplier: ENZO LIFE SCIENCES

Fluorogenic substrate for Alzheimer's Disease amyloid A4-generating enzymes and for the proteasome.

Supplier: ENZO LIFE SCIENCES

Highly-quenched, ultra-bright fluorogenic substrate for most MMPs. 6'-TAMRA fluorescence is thoroughly quenched by the TQ3 group until cleavage by MMPs separates the two moieties. The OMNIMMP® RED substrate offers key advantages over other MMP substrates.

Supplier: ENZO LIFE SCIENCES

HRP substrate.

Supplier: ENZO LIFE SCIENCES

Fluorogenic substrate cleaved by plasma kallikrein and kallikrein 8, but not plasmin; by papain; and by most cathepsins (cathepsins B, C/DPP-I, F, K/O2, L, L2/V, O, S, and X/Z). Ex.: 380 nm, Em.: 460 nm, although the following Ex/Em can also be used: 355,375/440,450.

Supplier: ENZO LIFE SCIENCES

This peptide sequence, EFpYAEVGRSPPDPAK, was selected by phage display analysis for optimal Shp-1 and Shp-2 phosphatase activities.

Supplier: ENZO LIFE SCIENCES

This peptide sequence, RRRAAEELDSRAGpSPQL, corresponds to the sequence of the epsilon subunit of elF2B surrounding Ser540, a target of GSK-3 (glycogen synthase kinase 3) phosphorylation, with the addition of a phosphoserine in the 4 position.

Supplier: Thermo Fisher Scientific

Elastase substrate V

Supplier: ENZO LIFE SCIENCES

HIGHDEF® Green AP Chromogen/Substrate is intended to be used in conjunction with alkaline phosphatase (AP)-based immunostaining or in situ hybridisation systems.

Supplier: ENZO LIFE SCIENCES

This peptide sequence, ARRKRKGSFFYGG, was selected from a peptide library for optimal phosphorylation by protein kinase C delta (PKCdelta).