48170 Results for: "Blender+Bags&pageNo=8"

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Anandamide (18:2, n-6) ≥98% (by TLC)

Supplier: Enzo Life Sciences

Endocannabinoid.

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Eicosapentaenoyl ethanolamide ≥98% (by TLC)

Supplier: Enzo Life Sciences

Eicosapentaenoyl ethanolamide ≥98% (by TLC)

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AAL-993 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Highly potent inhibitor of VEGFR-1 (IC50=130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM).

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(D-Pro1,2)-Retro-(D-HIV-Tat(48-57))

Supplier: Enzo Life Sciences

Jnk inhibitor

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7-Oxo-7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinoline-3-carboxylic acid ≥98% (by TLC)

Supplier: Enzo Life Sciences

CaM kinase kinase inhibitor

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Src inhibitor-1 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Potent, dual site (ATP domain and substrate-binding domain) Src and Lck kinase inhibitor (IC50=44 and 88nM respectively). VEGFR2 IC50=0.32μM; c-fms IC50=30μM.

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Potent, selective and irreversible inhibitor of MAG lipase (IC50=8nM vs 4µM for FAAH). JZL-184-treated mice displayed a number of CB1-dependent behavioral effects including analgesia, hypothermia and hypomotility as well as increased levels of 2-arachidonoylglycerol in the brain ( approx. 8-fold, with no effect on anandamide levels). JZL-184 produces a rapid and sustained blockade of brain 2-AG hydrolase activity in mice. It blocks neuropathic pain and enhances retrograde endocannabinoid signaling.

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BML-277 Chk2 inhibitor ≥98% (by TLC)

Supplier: Enzo Life Sciences

BML-277 is a highly selective inhibitor of Chk2 (IC50=15nM). It displays potent radioprotective activity and prevents apoptosis of human T cells subjected to ionizing radiation (EC50= 3-7.6µM). Useful tool for dissecting the role of Chk2 in cellular signaling.

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α-Hydroxyfarnesylphosphonic acid (synthetic) ≥98% (by TLC)

Supplier: Enzo Life Sciences

Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=30 nM) and in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=35.8 µM and 67 µM respectively). α-Hydroxyfarnesylphosphonic acid inhibited (1 µM) Ras processing in Ha-ras-transformed NIH 3T3 fibroblasts.

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Meleagrin (from Penicillium meleagrinum) ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Yellow oil

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Harpagoside ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Anti-inflammatory and anti-diabetic.

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Puerarin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

5-HT2c inhibitor

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Concanamycin A (from Streptomyces species) ≥98% (by HPLC)

Supplier: Enzo Life Sciences

White to off-white solid (sub-milligram quantities will appear as clear film)

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Blasticidin S hydrochloride (from Streptomyces griseochromogenes) ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Antibiotic.

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Hygromycin B (from Streptomyces hygroscopicus) ≥80% (by HPLC), liquid

Supplier: Enzo Life Sciences

Antibiotic and antiviral.

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Ammonium 1-pyrrolidinecarbodithioate ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Inhibitor of NF-κB activation (induced by either PMA or TNF-α) in various cell types.

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Wogonin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Anti-inflammatory and antioxidant.

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Diphenylboric acid-2-aminoethyl ester (2-APB) ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Cell permeable modulator of Ins(1,4,5)-P3-induced Ca²⁺ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca²⁺ entry (75µM).